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• W3096782067 startingPage "211" @default.
• W3096782067 abstract "The analysis of proteins in biological samples is highly desirable, given their connection to myriad biological functions and disease states, as well as the growing interest in the development of protein-based pharmaceuticals. The introduction and maturation of soft ionization methods, such as electrospray ionization and matrix-assisted laser desorption/ionization, have made mass spectrometry an indispensable tool for the analysis of proteins. Despite the availability of powerful instrumentation, sample preparation and fractionation remain among the most challenging aspects of protein analysis. This review summarizes these challenges and provides an overview of the state-of-the-art in sample preparation and fractionation of proteins for mass spectrometric analysis, with an emphasis on those used for top-down proteomic approaches. Biological fluids, particularly important for clinical and pharmaceutical applications and their characteristics are also discussed. While immunoaffinity-based methods are addressed, more attention is given to non-immunoaffinity-based methods, such as precipitation, coacervation, size exclusion, dialysis, solid-phase extraction, and electrophoresis. These techniques are presented in the context of a significant number of studies where they have been developed and utilized." @default.
• W3096782067 created "2020-11-09" @default.
• W3096782067 creator A5009046602 @default.
• W3096782067 creator A5020999349 @default.
• W3096782067 creator A5024419477 @default.
• W3096782067 creator A5091531976 @default.
• W3096782067 date "2020-11-19" @default.
• W3096782067 modified "2023-09-30" @default.
• W3096782067 title "Sample preparation and fractionation techniques for intact proteins for mass spectrometric analysis" @default.
• W3096782067 cites W119615050 @default.
• W3096782067 cites W148173047 @default.
• W3096782067 cites W1526743526 @default.
• W3096782067 cites W1532754033 @default.
• W3096782067 cites W1568341953 @default.
• W3096782067 cites W1586933226 @default.
• W3096782067 cites W1588243592 @default.
• W3096782067 cites W1606423922 @default.
• W3096782067 cites W166360239 @default.
• W3096782067 cites W1814977477 @default.
• W3096782067 cites W1831063844 @default.
• W3096782067 cites W1841261301 @default.
• W3096782067 cites W1955548622 @default.
• W3096782067 cites W1964739646 @default.
• W3096782067 cites W1964946814 @default.
• W3096782067 cites W1968601944 @default.
• W3096782067 cites W1968746767 @default.
• W3096782067 cites W1969050666 @default.
• W3096782067 cites W1969717580 @default.
• W3096782067 cites W1970171926 @default.
• W3096782067 cites W1970379769 @default.
• W3096782067 cites W1970696723 @default.
• W3096782067 cites W1971271087 @default.
• W3096782067 cites W1971873782 @default.
• W3096782067 cites W1972009772 @default.
• W3096782067 cites W1972395654 @default.
• W3096782067 cites W1972684192 @default.
• W3096782067 cites W1974428670 @default.
• W3096782067 cites W197490051 @default.
• W3096782067 cites W1975304761 @default.
• W3096782067 cites W1975849650 @default.
• W3096782067 cites W1976948929 @default.
• W3096782067 cites W1976951304 @default.
• W3096782067 cites W1979283760 @default.
• W3096782067 cites W1979650684 @default.
• W3096782067 cites W1979827657 @default.
• W3096782067 cites W1979928152 @default.
• W3096782067 cites W1980149555 @default.
• W3096782067 cites W1980314710 @default.
• W3096782067 cites W1983255121 @default.
• W3096782067 cites W1983647855 @default.
• W3096782067 cites W1985567418 @default.
• W3096782067 cites W1985923228 @default.
• W3096782067 cites W1985941856 @default.
• W3096782067 cites W1987782470 @default.
• W3096782067 cites W1988005933 @default.
• W3096782067 cites W1989265845 @default.
• W3096782067 cites W1989841960 @default.
• W3096782067 cites W1990577096 @default.
• W3096782067 cites W1991830571 @default.
• W3096782067 cites W1992198528 @default.
• W3096782067 cites W1994528342 @default.
• W3096782067 cites W1998245572 @default.
• W3096782067 cites W1999646474 @default.
• W3096782067 cites W2000138918 @default.
• W3096782067 cites W2001202214 @default.
• W3096782067 cites W2002870035 @default.
• W3096782067 cites W2003053754 @default.
• W3096782067 cites W2006986579 @default.
• W3096782067 cites W2007463094 @default.
• W3096782067 cites W2008171700 @default.
• W3096782067 cites W2009105593 @default.
• W3096782067 cites W2009278096 @default.
• W3096782067 cites W2010280805 @default.
• W3096782067 cites W2010625987 @default.
• W3096782067 cites W2012210404 @default.
• W3096782067 cites W2015864892 @default.
• W3096782067 cites W2018236745 @default.
• W3096782067 cites W2019297097 @default.
• W3096782067 cites W2020019994 @default.
• W3096782067 cites W2021264755 @default.
• W3096782067 cites W2022266651 @default.
• W3096782067 cites W2022285415 @default.
• W3096782067 cites W2023887263 @default.
• W3096782067 cites W2023994776 @default.
• W3096782067 cites W2023997855 @default.
• W3096782067 cites W2025055196 @default.
• W3096782067 cites W2025069411 @default.
• W3096782067 cites W2025524111 @default.
• W3096782067 cites W2026465178 @default.
• W3096782067 cites W2029016248 @default.
• W3096782067 cites W2030533925 @default.
• W3096782067 cites W2032266503 @default.
• W3096782067 cites W2033360508 @default.
• W3096782067 cites W2034621544 @default.
• W3096782067 cites W2035758756 @default.
• W3096782067 cites W2036485905 @default.
• W3096782067 cites W2036604104 @default.
• W3096782067 cites W2036743734 @default.

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