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- W3096914078 abstract "Abstract PROteolysis TArgeting Chimeras (PROTACs) are emerging as critical tools in biomedicinal chemistry and drug design, but they have limitations. These limitations include a lack of guiding principles when selecting suitable E3 ligases to induce ubiquitinylation, and problems degrading cell‐surface receptors. This Highlight outlines some recent advances that circumvent some of these limitations, and new alternative methods to induce selective protein degradation." @default.
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- W3096914078 date "2020-10-28" @default.
- W3096914078 modified "2023-10-18" @default.
- W3096914078 title "PROTAC Compatibilities, Degrading Cell‐Surface Receptors, and the Sticky Problem of Finding a Molecular Glue" @default.
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- W3096914078 doi "https://doi.org/10.1002/cmdc.202000683" @default.
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