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• W3097376425 startingPage "3592" @default.
• W3097376425 abstract "Multiple sclerosis (MS) is the most common autoimmune disease of the central nervous system (CNS), with an inflammatory demyelinating basis and a progressive course. The course of the disease is very diverse and unpredictable. Patients face many problems on a daily basis, such as problems with vision; sensory, balance, and gait disturbances; pain; muscle weakness; spasticity; tremor; urinary and fecal disorders; depression; and rapidly growing fatigue, which significantly influences quality of life among MS patients. Excessive fatigue occurs in most MS patients in all stages of this disease and is named MS-related fatigue. The crucial issue is the lack of effective treatment; therefore, this review focuses not only on the most common treatment methods, but also on additional novel therapies such as whole-body cryotherapy (WBC), functional electrical stimulation (FES), and non-invasive brain stimulation (NIBS). We also highlight the advantages and disadvantages of the most popular clinical scales used to measure fatigue. The entire understanding of the origins of MS-related fatigue may lead to the development of more effective strategies that can improve quality of life among MS patients. A literature search was performed using MEDLINE, EMBASE, and PEDro databases." @default.
• W3097376425 created "2020-11-09" @default.
• W3097376425 creator A5002645703 @default.
• W3097376425 creator A5015904478 @default.
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• W3097376425 creator A5052732434 @default.
• W3097376425 date "2020-11-07" @default.
• W3097376425 modified "2023-10-10" @default.
• W3097376425 title "New Strategies for Rehabilitation and Pharmacological Treatment of Fatigue Syndrome in Multiple Sclerosis" @default.
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• W3097376425 doi "https://doi.org/10.3390/jcm9113592" @default.
• W3097376425 hasPubMedCentralId "https://www.ncbi.nlm.nih.gov/pmc/articles/7695014" @default.
• W3097376425 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/33171768" @default.
• W3097376425 hasPublicationYear "2020" @default.
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