FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W3097676816> ?p ?o ?g. }

• W3097676816 endingPage "1429" @default.
• W3097676816 startingPage "1418" @default.
• W3097676816 abstract "Operationally tolerant kidney transplant recipients harbor an immunological signature, associated with low rejection risk, and focused on B lymphocytes. Here, we investigated whether patients with long-term transplantation and still on immunosuppressive therapy would present such a signature of low immunological rejection risk, compared to more recently transplanted patients. Of 114 kidney transplant recipients enrolled, 38 with more than 25 years of graft survival and stable graft function under calcineurin inhibitors, were matched with two different groups of transplanted patients (10-15 and 5-7 years after transplantation). Three phenotypes associated with low immunological rejection risk (Tfh, B and regulatory T cells), initially found in operationally tolerant kidney transplant recipients, and the composite score of tolerance (combination of six transcriptomic markers, age at transplantation and age at sampling) were analyzed. We found that very long-term patients were characterized by a significantly lower percentage of total B cells, a significantly higher proportion of CD24^HiCD38^Lo memory B cells, significantly fewer CD24^LoCD38^Lo naive B cells, and a significantly lower proportion of PD1^HiCCR7^Lo Tfh lymphocytes than more recently transplanted patients. This phenotype is associated with a positive composite score of tolerance in patients transplanted for more than 25 years. Thus, our study suggests a dual phenotype in very long-term kidney transplanted patients with an immunological profile associated with low rejection risk." @default.
• W3097676816 created "2020-11-09" @default.
• W3097676816 creator A5000832841 @default.
• W3097676816 creator A5006448601 @default.
• W3097676816 creator A5039888642 @default.
• W3097676816 creator A5052951076 @default.
• W3097676816 creator A5065216369 @default.
• W3097676816 creator A5065386977 @default.
• W3097676816 creator A5068352694 @default.
• W3097676816 creator A5070849935 @default.
• W3097676816 creator A5089422245 @default.
• W3097676816 date "2021-06-01" @default.
• W3097676816 modified "2023-10-12" @default.
• W3097676816 title "Clinical and immunological follow-up of very long-term kidney transplant recipients treated with calcineurin inhibitors indicates dual phenotypes" @default.
• W3097676816 cites W1583108216 @default.
• W3097676816 cites W1836216459 @default.
• W3097676816 cites W1955294545 @default.
• W3097676816 cites W1990847362 @default.
• W3097676816 cites W2010779631 @default.
• W3097676816 cites W2026694286 @default.
• W3097676816 cites W2039239630 @default.
• W3097676816 cites W2043016325 @default.
• W3097676816 cites W2066923345 @default.
• W3097676816 cites W2089774344 @default.
• W3097676816 cites W2089905782 @default.
• W3097676816 cites W2099803556 @default.
• W3097676816 cites W2103073605 @default.
• W3097676816 cites W2127001878 @default.
• W3097676816 cites W2141478377 @default.
• W3097676816 cites W2142814228 @default.
• W3097676816 cites W2147557958 @default.
• W3097676816 cites W2148001303 @default.
• W3097676816 cites W2150867915 @default.
• W3097676816 cites W2190524553 @default.
• W3097676816 cites W2298020624 @default.
• W3097676816 cites W2328925430 @default.
• W3097676816 cites W2331116430 @default.
• W3097676816 cites W2467825810 @default.
• W3097676816 cites W2468622292 @default.
• W3097676816 cites W2555594290 @default.
• W3097676816 cites W2594213072 @default.
• W3097676816 cites W2601871606 @default.
• W3097676816 cites W2747892832 @default.
• W3097676816 cites W2789403072 @default.
• W3097676816 cites W2789793371 @default.
• W3097676816 cites W2791950869 @default.
• W3097676816 cites W2792395829 @default.
• W3097676816 cites W2794125535 @default.
• W3097676816 cites W2805309348 @default.
• W3097676816 cites W2890859371 @default.
• W3097676816 cites W2910477949 @default.
• W3097676816 cites W2914649603 @default.
• W3097676816 cites W2981315000 @default.
• W3097676816 doi "https://doi.org/10.1016/j.kint.2020.09.036" @default.
• W3097676816 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/33137335" @default.
• W3097676816 hasPublicationYear "2021" @default.
• W3097676816 type Work @default.
• W3097676816 sameAs 3097676816 @default.
• W3097676816 citedByCount "7" @default.
• W3097676816 countsByYear W30976768162021 @default.
• W3097676816 countsByYear W30976768162022 @default.
• W3097676816 countsByYear W30976768162023 @default.
• W3097676816 crossrefType "journal-article" @default.
• W3097676816 hasAuthorship W3097676816A5000832841 @default.
• W3097676816 hasAuthorship W3097676816A5006448601 @default.
• W3097676816 hasAuthorship W3097676816A5039888642 @default.
• W3097676816 hasAuthorship W3097676816A5052951076 @default.
• W3097676816 hasAuthorship W3097676816A5065216369 @default.
• W3097676816 hasAuthorship W3097676816A5065386977 @default.
• W3097676816 hasAuthorship W3097676816A5068352694 @default.
• W3097676816 hasAuthorship W3097676816A5070849935 @default.
• W3097676816 hasAuthorship W3097676816A5089422245 @default.
• W3097676816 hasBestOaLocation W30976768161 @default.
• W3097676816 hasConcept C104317684 @default.
• W3097676816 hasConcept C121332964 @default.
• W3097676816 hasConcept C126322002 @default.
• W3097676816 hasConcept C127716648 @default.
• W3097676816 hasConcept C128057223 @default.
• W3097676816 hasConcept C203014093 @default.
• W3097676816 hasConcept C2780091579 @default.
• W3097676816 hasConcept C2780303639 @default.
• W3097676816 hasConcept C2909675724 @default.
• W3097676816 hasConcept C2911091166 @default.
• W3097676816 hasConcept C2994498544 @default.
• W3097676816 hasConcept C54355233 @default.
• W3097676816 hasConcept C61797465 @default.
• W3097676816 hasConcept C62520636 @default.
• W3097676816 hasConcept C71924100 @default.
• W3097676816 hasConcept C86803240 @default.
• W3097676816 hasConceptScore W3097676816C104317684 @default.
• W3097676816 hasConceptScore W3097676816C121332964 @default.
• W3097676816 hasConceptScore W3097676816C126322002 @default.
• W3097676816 hasConceptScore W3097676816C127716648 @default.
• W3097676816 hasConceptScore W3097676816C128057223 @default.
• W3097676816 hasConceptScore W3097676816C203014093 @default.
• W3097676816 hasConceptScore W3097676816C2780091579 @default.
• W3097676816 hasConceptScore W3097676816C2780303639 @default.
• W3097676816 hasConceptScore W3097676816C2909675724 @default.

• next