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- W3097767265 abstract "Infection, trauma, and chemical exposure of the ocular surface can severely damage the cornea, resulting in visually significant stromal scars. Current medical treatments are ineffective in mitigating corneal scarring, and corneal transplantation is the only therapy able to restore vision in these eyes. However, because of a severe shortage of corneal tissues, risks of blinding complications associated with corneal transplants, and a higher rate of graft failure in these eyes, an effective and deliverable alternative therapy for the prevention and treatment of corneal scarring remains a significant unmet medical need globally. In recent years, the therapeutic potential of extracellular vesicles (EVs) secreted by cells to mediate cell-cell communication has been a topic of increasing interest. EVs derived from mesenchymal stem cells, in particular human corneal stromal stem cells, have antifibrotic, anti-inflammatory, and regenerative effects in injured corneas. The exact mechanism of action of these functional EVs are largely unknown. Therapeutic development of EVs is at an early stage and warrants further preclinical studies." @default.
- W3097767265 created "2020-11-09" @default.
- W3097767265 creator A5059316189 @default.
- W3097767265 creator A5077317766 @default.
- W3097767265 creator A5090962207 @default.
- W3097767265 date "2020-11-02" @default.
- W3097767265 modified "2023-10-03" @default.
- W3097767265 title "Therapeutic Potential of Extracellular Vesicles for the Treatment of Corneal Injuries and Scars" @default.
- W3097767265 cites W1970892084 @default.
- W3097767265 cites W1983279888 @default.
- W3097767265 cites W1989591249 @default.
- W3097767265 cites W2005865889 @default.
- W3097767265 cites W2006155420 @default.
- W3097767265 cites W2014067185 @default.
- W3097767265 cites W2014882299 @default.
- W3097767265 cites W2021612760 @default.
- W3097767265 cites W2028000551 @default.
- W3097767265 cites W2040016239 @default.
- W3097767265 cites W2041007227 @default.
- W3097767265 cites W2042343633 @default.
- W3097767265 cites W2045372639 @default.
- W3097767265 cites W2051545628 @default.
- W3097767265 cites W2059822562 @default.
- W3097767265 cites W2068367752 @default.
- W3097767265 cites W2091428132 @default.
- W3097767265 cites W2098525297 @default.
- W3097767265 cites W2106583271 @default.
- W3097767265 cites W2110662032 @default.
- W3097767265 cites W2112980158 @default.
- W3097767265 cites W2118854821 @default.
- W3097767265 cites W2121354606 @default.
- W3097767265 cites W2123215356 @default.
- W3097767265 cites W2165186135 @default.
- W3097767265 cites W2170852633 @default.
- W3097767265 cites W2181511066 @default.
- W3097767265 cites W2219429396 @default.
- W3097767265 cites W2237548841 @default.
- W3097767265 cites W2257714393 @default.
- W3097767265 cites W2290775492 @default.
- W3097767265 cites W2295603197 @default.
- W3097767265 cites W2316159156 @default.
- W3097767265 cites W2401390149 @default.
- W3097767265 cites W2406264223 @default.
- W3097767265 cites W2426503034 @default.
- W3097767265 cites W2476666813 @default.
- W3097767265 cites W2480892659 @default.
- W3097767265 cites W2487947432 @default.
- W3097767265 cites W2508710172 @default.
- W3097767265 cites W2554427090 @default.
- W3097767265 cites W2581635594 @default.
- W3097767265 cites W2586190953 @default.
- W3097767265 cites W2593892840 @default.
- W3097767265 cites W2597669146 @default.
- W3097767265 cites W2605484523 @default.
- W3097767265 cites W2625985824 @default.
- W3097767265 cites W2742443818 @default.
- W3097767265 cites W2765917805 @default.
- W3097767265 cites W2790030161 @default.
- W3097767265 cites W2790927699 @default.
- W3097767265 cites W2801659237 @default.
- W3097767265 cites W2806388412 @default.
- W3097767265 cites W2886368464 @default.
- W3097767265 cites W2889060171 @default.
- W3097767265 cites W2897177790 @default.
- W3097767265 cites W2899171011 @default.
- W3097767265 cites W2899701201 @default.
- W3097767265 cites W2900756811 @default.
- W3097767265 cites W2910893554 @default.
- W3097767265 cites W2911395102 @default.
- W3097767265 cites W2919278937 @default.
- W3097767265 cites W2927404384 @default.
- W3097767265 cites W2942144529 @default.
- W3097767265 cites W2954441299 @default.
- W3097767265 cites W2956004045 @default.
- W3097767265 cites W2957989341 @default.
- W3097767265 cites W2962176767 @default.
- W3097767265 cites W2962663587 @default.
- W3097767265 cites W2970234153 @default.
- W3097767265 cites W2972357900 @default.
- W3097767265 cites W2976115119 @default.
- W3097767265 cites W2987211515 @default.
- W3097767265 cites W2991416247 @default.
- W3097767265 cites W2995958047 @default.
- W3097767265 cites W2996303717 @default.
- W3097767265 cites W3018428160 @default.
- W3097767265 cites W4231133011 @default.
- W3097767265 cites W4234943916 @default.
- W3097767265 cites W4236232013 @default.
- W3097767265 cites W4237050961 @default.
- W3097767265 cites W4239177710 @default.
- W3097767265 cites W4241224678 @default.
- W3097767265 cites W4248889068 @default.
- W3097767265 cites W4250808398 @default.
- W3097767265 cites W4255505961 @default.
- W3097767265 cites W4313777 @default.
- W3097767265 doi "https://doi.org/10.1167/tvst.9.12.1" @default.
- W3097767265 hasPubMedCentralId "https://www.ncbi.nlm.nih.gov/pmc/articles/7645240" @default.
- W3097767265 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/33200043" @default.