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• W3097776377 abstract "The extensive sequence data generated from SARS-CoV-2 during the 2020 pandemic has facilitated the study of viral genome evolution over a brief period of time. This has highlighted instances of directional mutation pressures exerted on the SARS-CoV-2 genome from host antiviral defense systems. In this brief review we describe three such human defense mechanisms, the apolipoprotein B mRNA editing catalytic polypeptide-like proteins (APOBEC), adenosine deaminase acting on RNA proteins (ADAR), and reactive oxygen species (ROS), and discuss their potential implications on SARS-CoV-2 evolution." @default.
• W3097776377 created "2020-11-09" @default.
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• W3097776377 date "2021-01-01" @default.
• W3097776377 modified "2023-10-16" @default.
• W3097776377 title "Host-directed editing of the SARS-CoV-2 genome" @default.
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• W3097776377 doi "https://doi.org/10.1016/j.bbrc.2020.10.092" @default.
• W3097776377 hasPubMedCentralId "https://www.ncbi.nlm.nih.gov/pmc/articles/7643664" @default.
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