Matches in SemOpenAlex for { <https://semopenalex.org/work/W3098497759> ?p ?o ?g. }
Showing items 1 to 82 of
82
with 100 items per page.
- W3098497759 endingPage "190" @default.
- W3098497759 startingPage "185" @default.
- W3098497759 abstract "Standardization of laboratory tests can be a long process, and this is the case with regards to the methods used to measure hemoglobin A2 (HbA2), an important marker for beta-thalassemia and other thalassemic conditions. The IFCC standardization project started in 2004, and it took at least 15 years before developing a reference measurement procedure, defining and producing calibrators and certified reference materials. A series of steps have to be undertaken in order to promote the standardization in the field, a process involving a number of stakeholders (manufacturers, scientific societies, national health bodies, laboratory professionals, clinicians). In this work we describe some possible process indicators, in order to assure that the standardization will have internal and external validity and be effective for a long time. These indicators concern the inter-method studies, elaboration of External Quality Assessment Schemes, and the evaluation of the yearly distributions of HbA2 measurements collected in selected laboratories. Preliminary results are reported concerning the yearly distributions of HbA2, collected in two different locations, and using different analytical methods. Median yearly values were found very constant over the years, but different between methods. On the other side, results obtained on the same specimens using two different techniques, proved that results by capillary electrophoresis in 2 out of the 3 years of observation, were significantly lower than those by HPLC. In this document we report what has been done so far, and what has to be done to achieve the standardization of the measurement of HbA2 worldwide." @default.
- W3098497759 created "2020-11-23" @default.
- W3098497759 creator A5018066889 @default.
- W3098497759 creator A5057163726 @default.
- W3098497759 creator A5071876116 @default.
- W3098497759 date "2021-01-01" @default.
- W3098497759 modified "2023-10-14" @default.
- W3098497759 title "A roadmap for the standardization of hemoglobin A2" @default.
- W3098497759 cites W1912578906 @default.
- W3098497759 cites W1967354181 @default.
- W3098497759 cites W1976329147 @default.
- W3098497759 cites W1985103439 @default.
- W3098497759 cites W1999163342 @default.
- W3098497759 cites W2002190262 @default.
- W3098497759 cites W2004624314 @default.
- W3098497759 cites W2030162700 @default.
- W3098497759 cites W2031834706 @default.
- W3098497759 cites W2060298956 @default.
- W3098497759 cites W2094140382 @default.
- W3098497759 cites W2109049123 @default.
- W3098497759 cites W2166252825 @default.
- W3098497759 cites W2168511998 @default.
- W3098497759 cites W2396207226 @default.
- W3098497759 cites W2539528650 @default.
- W3098497759 cites W2601132995 @default.
- W3098497759 cites W2775245287 @default.
- W3098497759 cites W2897335047 @default.
- W3098497759 cites W2902048178 @default.
- W3098497759 cites W3187992181 @default.
- W3098497759 cites W4230521206 @default.
- W3098497759 cites W61817131 @default.
- W3098497759 doi "https://doi.org/10.1016/j.cca.2020.11.008" @default.
- W3098497759 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/33181152" @default.
- W3098497759 hasPublicationYear "2021" @default.
- W3098497759 type Work @default.
- W3098497759 sameAs 3098497759 @default.
- W3098497759 citedByCount "8" @default.
- W3098497759 countsByYear W30984977592021 @default.
- W3098497759 countsByYear W30984977592023 @default.
- W3098497759 crossrefType "journal-article" @default.
- W3098497759 hasAuthorship W3098497759A5018066889 @default.
- W3098497759 hasAuthorship W3098497759A5057163726 @default.
- W3098497759 hasAuthorship W3098497759A5071876116 @default.
- W3098497759 hasConcept C111919701 @default.
- W3098497759 hasConcept C127413603 @default.
- W3098497759 hasConcept C188087704 @default.
- W3098497759 hasConcept C201995342 @default.
- W3098497759 hasConcept C21547014 @default.
- W3098497759 hasConcept C2778618615 @default.
- W3098497759 hasConcept C2780451532 @default.
- W3098497759 hasConcept C41008148 @default.
- W3098497759 hasConcept C98045186 @default.
- W3098497759 hasConceptScore W3098497759C111919701 @default.
- W3098497759 hasConceptScore W3098497759C127413603 @default.
- W3098497759 hasConceptScore W3098497759C188087704 @default.
- W3098497759 hasConceptScore W3098497759C201995342 @default.
- W3098497759 hasConceptScore W3098497759C21547014 @default.
- W3098497759 hasConceptScore W3098497759C2778618615 @default.
- W3098497759 hasConceptScore W3098497759C2780451532 @default.
- W3098497759 hasConceptScore W3098497759C41008148 @default.
- W3098497759 hasConceptScore W3098497759C98045186 @default.
- W3098497759 hasFunder F4320328686 @default.
- W3098497759 hasLocation W30984977591 @default.
- W3098497759 hasOpenAccess W3098497759 @default.
- W3098497759 hasPrimaryLocation W30984977591 @default.
- W3098497759 hasRelatedWork W1540871478 @default.
- W3098497759 hasRelatedWork W1975570126 @default.
- W3098497759 hasRelatedWork W2066396794 @default.
- W3098497759 hasRelatedWork W2366734808 @default.
- W3098497759 hasRelatedWork W2376963063 @default.
- W3098497759 hasRelatedWork W2378767206 @default.
- W3098497759 hasRelatedWork W2748952813 @default.
- W3098497759 hasRelatedWork W282641168 @default.
- W3098497759 hasRelatedWork W2899084033 @default.
- W3098497759 hasRelatedWork W328308450 @default.
- W3098497759 hasVolume "512" @default.
- W3098497759 isParatext "false" @default.
- W3098497759 isRetracted "false" @default.
- W3098497759 magId "3098497759" @default.
- W3098497759 workType "article" @default.