FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W3098569689> ?p ?o ?g. }

• W3098569689 abstract "Key to collective cell migration is the ability of cells to rearrange their position with respect to their neighbors. Recent theory and experiments demonstrated that cellular rearrangements are facilitated by cell shape, with cells having more elongated shapes and greater perimeters more easily sliding past their neighbors within the cell layer. Though it is thought that cell perimeter is controlled primarily by cortical tension and adhesion at each cell's periphery, experimental testing of this hypothesis has produced conflicting results. Here we studied collective cell migration in an epithelial monolayer by measuring forces, cell perimeters, and motion, and found all three to decrease with either increased cell density or inhibition of cell contraction. In contrast to previous understanding, the data suggest that cell shape and rearrangements are controlled not by cortical tension or adhesion at the cell periphery but rather by the stress fibers that produce tractions at the cell-substrate interface. This finding is confirmed by an experiment showing that increasing tractions reverses the effect of density on cell shape and rearrangements. Our study therefore reduces the focus on the cell periphery by establishing cell-substrate traction as a major physical factor controlling cell shape and motion in collective cell migration." @default.
• W3098569689 created "2020-11-23" @default.
• W3098569689 creator A5014605997 @default.
• W3098569689 creator A5045547369 @default.
• W3098569689 date "2020-01-23" @default.
• W3098569689 modified "2023-10-12" @default.
• W3098569689 title "Tractions and Stress Fibers Control Cell Shape and Rearrangements in Collective Cell Migration" @default.
• W3098569689 cites W1809226463 @default.
• W3098569689 cites W1811460226 @default.
• W3098569689 cites W1880645299 @default.
• W3098569689 cites W1966714020 @default.
• W3098569689 cites W1967489328 @default.
• W3098569689 cites W1974655589 @default.
• W3098569689 cites W1999531676 @default.
• W3098569689 cites W2000217624 @default.
• W3098569689 cites W2016539608 @default.
• W3098569689 cites W2027840351 @default.
• W3098569689 cites W2030041577 @default.
• W3098569689 cites W2030274279 @default.
• W3098569689 cites W2032943562 @default.
• W3098569689 cites W2033575518 @default.
• W3098569689 cites W2033739998 @default.
• W3098569689 cites W2034440356 @default.
• W3098569689 cites W2056805807 @default.
• W3098569689 cites W2068939664 @default.
• W3098569689 cites W2081873450 @default.
• W3098569689 cites W2084408246 @default.
• W3098569689 cites W2091389429 @default.
• W3098569689 cites W2094441795 @default.
• W3098569689 cites W2097970956 @default.
• W3098569689 cites W2103495097 @default.
• W3098569689 cites W2110834542 @default.
• W3098569689 cites W2124186838 @default.
• W3098569689 cites W2125862744 @default.
• W3098569689 cites W2126306109 @default.
• W3098569689 cites W2145013849 @default.
• W3098569689 cites W2146835460 @default.
• W3098569689 cites W2155154349 @default.
• W3098569689 cites W2158544937 @default.
• W3098569689 cites W2160780620 @default.
• W3098569689 cites W2170160122 @default.
• W3098569689 cites W2173637151 @default.
• W3098569689 cites W2184806432 @default.
• W3098569689 cites W2218510376 @default.
• W3098569689 cites W2409502065 @default.
• W3098569689 cites W2474539144 @default.
• W3098569689 cites W2516983792 @default.
• W3098569689 cites W2525689442 @default.
• W3098569689 cites W2557984644 @default.
• W3098569689 cites W2581589183 @default.
• W3098569689 cites W2602765053 @default.
• W3098569689 cites W2615584725 @default.
• W3098569689 cites W2758842856 @default.
• W3098569689 cites W2774885992 @default.
• W3098569689 cites W2793058138 @default.
• W3098569689 cites W2884081828 @default.
• W3098569689 cites W2891109293 @default.
• W3098569689 cites W2891157515 @default.
• W3098569689 cites W2953138240 @default.
• W3098569689 cites W2962681597 @default.
• W3098569689 cites W2963873576 @default.
• W3098569689 cites W2967822574 @default.
• W3098569689 doi "https://doi.org/10.1103/physrevx.10.011016" @default.
• W3098569689 hasPublicationYear "2020" @default.
• W3098569689 type Work @default.
• W3098569689 sameAs 3098569689 @default.
• W3098569689 citedByCount "17" @default.
• W3098569689 countsByYear W30985696892020 @default.
• W3098569689 countsByYear W30985696892021 @default.
• W3098569689 countsByYear W30985696892022 @default.
• W3098569689 countsByYear W30985696892023 @default.
• W3098569689 crossrefType "journal-article" @default.
• W3098569689 hasAuthorship W3098569689A5014605997 @default.
• W3098569689 hasAuthorship W3098569689A5045547369 @default.
• W3098569689 hasBestOaLocation W30985696891 @default.
• W3098569689 hasConcept C12554922 @default.
• W3098569689 hasConcept C137738243 @default.
• W3098569689 hasConcept C1491633281 @default.
• W3098569689 hasConcept C159985019 @default.
• W3098569689 hasConcept C185592680 @default.
• W3098569689 hasConcept C192562407 @default.
• W3098569689 hasConcept C55493867 @default.
• W3098569689 hasConcept C84416704 @default.
• W3098569689 hasConcept C85789140 @default.
• W3098569689 hasConcept C85813293 @default.
• W3098569689 hasConcept C86803240 @default.
• W3098569689 hasConceptScore W3098569689C12554922 @default.
• W3098569689 hasConceptScore W3098569689C137738243 @default.
• W3098569689 hasConceptScore W3098569689C1491633281 @default.
• W3098569689 hasConceptScore W3098569689C159985019 @default.
• W3098569689 hasConceptScore W3098569689C185592680 @default.
• W3098569689 hasConceptScore W3098569689C192562407 @default.
• W3098569689 hasConceptScore W3098569689C55493867 @default.
• W3098569689 hasConceptScore W3098569689C84416704 @default.
• W3098569689 hasConceptScore W3098569689C85789140 @default.
• W3098569689 hasConceptScore W3098569689C85813293 @default.
• W3098569689 hasConceptScore W3098569689C86803240 @default.
• W3098569689 hasFunder F4320306076 @default.
• W3098569689 hasFunder F4320309434 @default.
• W3098569689 hasIssue "1" @default.

• next