FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W3099083642> ?p ?o ?g. }

• W3099083642 endingPage "192" @default.
• W3099083642 startingPage "182" @default.
• W3099083642 abstract "Amblyopia is a common perceptual disorder resulting from abnormal visual input during development. The clinical presentation and visual deficits associated with amblyopia are well characterized. Less is known however, about amblyopia’s impact on the central nervous system (CNS). While early insights into the neuropathophysiology of amblyopia have been based on findings from animal models and postmortem human studies, recent advances in noninvasive magnetic resonance imaging (MRI) techniques have enabled the study of amblyopia’s effects in vivo. We review recent retinal and neuroimaging research documenting amblyopia’s structural and functional impact on the CNS. Clinical imaging provides some evidence for retinal and optic nerve abnormalities in amblyopic eyes, although the overall picture remains inconclusive. Neuroimaging studies report clearer changes in both structure and function of the visual pathways. In the optic nerves, optic tracts, and optic radiations of individuals with amblyopia, white-matter integrity is decreased. In the lateral geniculate nuclei, gray matter volume is decreased and neural activity is reduced. Reduced responses are also seen in the amblyopic primary visual cortex and extrastriate areas. Overall, amblyopia impacts structure and function at multiple sites along the visual processing hierarchy. Moreover, there is some evidence that amblyopia’s impact on the CNS depends on its etiology, with different patterns of results for strabismic and anisometropic amblyopia. To clarify the impact of amblyopia on the CNS, simultaneous collection of retinal, neural, and perceptual measures should be employed. Such an approach will help (1) distinguish cause and effect of amblyopic impairments, (2) separate the impact of amblyopia from other superimposed conditions, and (3) identify the importance of amblyopic etiology to specific neural and perceptual deficits." @default.
• W3099083642 created "2020-11-23" @default.
• W3099083642 creator A5053612623 @default.
• W3099083642 creator A5068077781 @default.
• W3099083642 creator A5069043024 @default.
• W3099083642 creator A5090763037 @default.
• W3099083642 date "2020-10-01" @default.
• W3099083642 modified "2023-09-27" @default.
• W3099083642 title "Impact of Amblyopia on the Central Nervous System" @default.
• W3099083642 cites W1482811037 @default.
• W3099083642 cites W1550990184 @default.
• W3099083642 cites W1606268735 @default.
• W3099083642 cites W1720159458 @default.
• W3099083642 cites W1963930878 @default.
• W3099083642 cites W1964848908 @default.
• W3099083642 cites W1966027496 @default.
• W3099083642 cites W1966144490 @default.
• W3099083642 cites W1967992950 @default.
• W3099083642 cites W1969984007 @default.
• W3099083642 cites W1970000541 @default.
• W3099083642 cites W1972954672 @default.
• W3099083642 cites W1975308537 @default.
• W3099083642 cites W1978211767 @default.
• W3099083642 cites W1982200549 @default.
• W3099083642 cites W1984730681 @default.
• W3099083642 cites W1987777621 @default.
• W3099083642 cites W1989182370 @default.
• W3099083642 cites W1990223835 @default.
• W3099083642 cites W1994469944 @default.
• W3099083642 cites W1996658335 @default.
• W3099083642 cites W1999316812 @default.
• W3099083642 cites W2000295093 @default.
• W3099083642 cites W2001485952 @default.
• W3099083642 cites W2003268023 @default.
• W3099083642 cites W2004006028 @default.
• W3099083642 cites W2005931906 @default.
• W3099083642 cites W2019276769 @default.
• W3099083642 cites W2021694297 @default.
• W3099083642 cites W2023812395 @default.
• W3099083642 cites W2037703270 @default.
• W3099083642 cites W2038327846 @default.
• W3099083642 cites W2039406936 @default.
• W3099083642 cites W2042971608 @default.
• W3099083642 cites W2046760778 @default.
• W3099083642 cites W2049658101 @default.
• W3099083642 cites W2050398584 @default.
• W3099083642 cites W2052380352 @default.
• W3099083642 cites W2054709077 @default.
• W3099083642 cites W2057702936 @default.
• W3099083642 cites W2060293198 @default.
• W3099083642 cites W2062593520 @default.
• W3099083642 cites W2063587125 @default.
• W3099083642 cites W2063944996 @default.
• W3099083642 cites W2064647097 @default.
• W3099083642 cites W2068756040 @default.
• W3099083642 cites W2071541021 @default.
• W3099083642 cites W2072411587 @default.
• W3099083642 cites W2076848620 @default.
• W3099083642 cites W2077809709 @default.
• W3099083642 cites W2079290657 @default.
• W3099083642 cites W2082785515 @default.
• W3099083642 cites W2083695919 @default.
• W3099083642 cites W2084146775 @default.
• W3099083642 cites W2088171581 @default.
• W3099083642 cites W2088805624 @default.
• W3099083642 cites W2091955527 @default.
• W3099083642 cites W2095928345 @default.
• W3099083642 cites W2097620211 @default.
• W3099083642 cites W2104220712 @default.
• W3099083642 cites W2105500446 @default.
• W3099083642 cites W2111308791 @default.
• W3099083642 cites W2116658562 @default.
• W3099083642 cites W2120601203 @default.
• W3099083642 cites W2124027429 @default.
• W3099083642 cites W2125843028 @default.
• W3099083642 cites W2126061653 @default.
• W3099083642 cites W2126472970 @default.
• W3099083642 cites W2127233095 @default.
• W3099083642 cites W2129387238 @default.
• W3099083642 cites W2135792442 @default.
• W3099083642 cites W2141067690 @default.
• W3099083642 cites W2150031206 @default.
• W3099083642 cites W2157172876 @default.
• W3099083642 cites W2167585304 @default.
• W3099083642 cites W2179375682 @default.
• W3099083642 cites W2184778991 @default.
• W3099083642 cites W2189833931 @default.
• W3099083642 cites W2204047724 @default.
• W3099083642 cites W2303836768 @default.
• W3099083642 cites W2322988415 @default.
• W3099083642 cites W2538237401 @default.
• W3099083642 cites W2555702487 @default.
• W3099083642 cites W2591560067 @default.
• W3099083642 cites W2604093114 @default.
• W3099083642 cites W2767680160 @default.
• W3099083642 cites W2767921294 @default.
• W3099083642 cites W2787656726 @default.
• W3099083642 cites W2792238758 @default.

• next