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• W3099152055 abstract "Abstract Variability in red blood cell volumes (distribution width, RDW) increases with age and is strongly predictive of mortality, incident coronary heart disease and cancer. We investigated inherited genetic variation associated with RDW in 166,666 UK Biobank human volunteers. A large proportion RDW is explained by genetic variants (29%), especially in the older group (60+ year olds, 33.8%, Although increased RDW is predictive of cardiovascular outcomes, this was not explained by known CVD or related lipid genetic risks. The predictive value of RDW for a range of negative health outcomes may in part be due to variants influencing fundamental pathways of aging." @default.
• W3099152055 created "2020-11-23" @default.
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• W3099152055 date "2017-04-18" @default.
• W3099152055 modified "2023-09-26" @default.
• W3099152055 title "Red Blood Cell Distribution Width: genetic evidence for aging pathways in 116,666 volunteers: Genetic influences on Red Blood Cell variation" @default.
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