Matches in SemOpenAlex for { <https://semopenalex.org/work/W3099246552> ?p ?o ?g. }
- W3099246552 endingPage "8" @default.
- W3099246552 startingPage "1" @default.
- W3099246552 abstract "Abstract Objective: Vitamin D deficiency may be a clinical problem in patients with addictions. The authors systematically searched for studies addressing vitamin D and addiction and develop a hypothesis which can direct future research of the possible mechanistic role of vitamin D in the process of addiction. Methods: Systematic review of the literature found in PubMed and EMBASE followed by narrative review combined with clinical experiences leading to hypotheses for future research. Results: Only five articles were identified about a role of vitamin D in the pathophysiology of addiction. Their results are in line with a possible influence of vitamin D in dopaminergic transmission. The cerebral vitamin D status depends on the functionality of genetic variants of vitamin D receptor and other involved genes. Routine serum calcidiol levels may not adequately reflect cerebral vitamin D status. Uncertainty exists regarding appropriate calcidiol blood levels and proper dosages for affecting the central nervous system (CNS). Conclusions: The putative pathophysiological role of vitamin D in substance abuse has been insufficiently studied which calls to more studies how to measure cerebral vitamin D status in clinical practice. Research is indicated whether vitamin D supplementation should use higher dosages and aim to reach higher calcidiol serum levels. Measuring dopaminergic functioning within the prefrontal cortex as reflected by neuropsychological tests selected as suitable could be a appropriate proxy for the cerebral vitamin D status when studying the pharmacogenomics of this functionality in patients." @default.
- W3099246552 created "2020-11-23" @default.
- W3099246552 creator A5000388464 @default.
- W3099246552 creator A5085239387 @default.
- W3099246552 date "2020-11-13" @default.
- W3099246552 modified "2023-09-27" @default.
- W3099246552 title "Putative role of vitamin D in the mechanism of alcoholism and other addictions – a hypothesis" @default.
- W3099246552 cites W1779549872 @default.
- W3099246552 cites W1965514557 @default.
- W3099246552 cites W1970124511 @default.
- W3099246552 cites W1974173211 @default.
- W3099246552 cites W1975970478 @default.
- W3099246552 cites W1979851608 @default.
- W3099246552 cites W1980637507 @default.
- W3099246552 cites W2005675731 @default.
- W3099246552 cites W2008755739 @default.
- W3099246552 cites W2016791847 @default.
- W3099246552 cites W2022090925 @default.
- W3099246552 cites W2046143181 @default.
- W3099246552 cites W2063562664 @default.
- W3099246552 cites W2066848874 @default.
- W3099246552 cites W2086157614 @default.
- W3099246552 cites W2086288529 @default.
- W3099246552 cites W2086985357 @default.
- W3099246552 cites W2087559183 @default.
- W3099246552 cites W2089290815 @default.
- W3099246552 cites W2091810325 @default.
- W3099246552 cites W2092410657 @default.
- W3099246552 cites W2102464054 @default.
- W3099246552 cites W2128847469 @default.
- W3099246552 cites W2146907112 @default.
- W3099246552 cites W2163494713 @default.
- W3099246552 cites W2166474550 @default.
- W3099246552 cites W2166983474 @default.
- W3099246552 cites W2170022218 @default.
- W3099246552 cites W2234540276 @default.
- W3099246552 cites W2335257837 @default.
- W3099246552 cites W2426421998 @default.
- W3099246552 cites W2503766608 @default.
- W3099246552 cites W2544990625 @default.
- W3099246552 cites W2566551570 @default.
- W3099246552 cites W2570746747 @default.
- W3099246552 cites W2587983561 @default.
- W3099246552 cites W2610941184 @default.
- W3099246552 cites W2619748449 @default.
- W3099246552 cites W2626191380 @default.
- W3099246552 cites W2696457852 @default.
- W3099246552 cites W2811419726 @default.
- W3099246552 cites W2912529245 @default.
- W3099246552 cites W2920871373 @default.
- W3099246552 cites W2947434531 @default.
- W3099246552 cites W2948445178 @default.
- W3099246552 cites W3022354617 @default.
- W3099246552 cites W3047395496 @default.
- W3099246552 doi "https://doi.org/10.1017/neu.2020.41" @default.
- W3099246552 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/33183376" @default.
- W3099246552 hasPublicationYear "2020" @default.
- W3099246552 type Work @default.
- W3099246552 sameAs 3099246552 @default.
- W3099246552 citedByCount "2" @default.
- W3099246552 countsByYear W30992465522022 @default.
- W3099246552 crossrefType "journal-article" @default.
- W3099246552 hasAuthorship W3099246552A5000388464 @default.
- W3099246552 hasAuthorship W3099246552A5085239387 @default.
- W3099246552 hasBestOaLocation W30992465521 @default.
- W3099246552 hasConcept C111472728 @default.
- W3099246552 hasConcept C118552586 @default.
- W3099246552 hasConcept C124490489 @default.
- W3099246552 hasConcept C126322002 @default.
- W3099246552 hasConcept C137183658 @default.
- W3099246552 hasConcept C138885662 @default.
- W3099246552 hasConcept C14216870 @default.
- W3099246552 hasConcept C15744967 @default.
- W3099246552 hasConcept C169760540 @default.
- W3099246552 hasConcept C169900460 @default.
- W3099246552 hasConcept C179639408 @default.
- W3099246552 hasConcept C2776940978 @default.
- W3099246552 hasConcept C40010229 @default.
- W3099246552 hasConcept C48856860 @default.
- W3099246552 hasConcept C513476851 @default.
- W3099246552 hasConcept C60644358 @default.
- W3099246552 hasConcept C71924100 @default.
- W3099246552 hasConcept C86803240 @default.
- W3099246552 hasConcept C89611455 @default.
- W3099246552 hasConceptScore W3099246552C111472728 @default.
- W3099246552 hasConceptScore W3099246552C118552586 @default.
- W3099246552 hasConceptScore W3099246552C124490489 @default.
- W3099246552 hasConceptScore W3099246552C126322002 @default.
- W3099246552 hasConceptScore W3099246552C137183658 @default.
- W3099246552 hasConceptScore W3099246552C138885662 @default.
- W3099246552 hasConceptScore W3099246552C14216870 @default.
- W3099246552 hasConceptScore W3099246552C15744967 @default.
- W3099246552 hasConceptScore W3099246552C169760540 @default.
- W3099246552 hasConceptScore W3099246552C169900460 @default.
- W3099246552 hasConceptScore W3099246552C179639408 @default.
- W3099246552 hasConceptScore W3099246552C2776940978 @default.
- W3099246552 hasConceptScore W3099246552C40010229 @default.
- W3099246552 hasConceptScore W3099246552C48856860 @default.