Matches in SemOpenAlex for { <https://semopenalex.org/work/W3099832882> ?p ?o ?g. }
Showing items 1 to 100 of
100
with 100 items per page.
- W3099832882 endingPage "302" @default.
- W3099832882 startingPage "297" @default.
- W3099832882 abstract "Critically ill patients frequently have hyperglycemia. This event may reflect severe stress with an imbalance between anabolic hormones and catabolic hormones. Alternatively, it may reflect alterations in either insulin levels or insulin function. Insulin is a pleiotropic hormone with multiple important metabolic effects. In patients with sepsis, insulin levels are increased but insulin sensitivity is decreased. However, there is variability in insulin sensitivity, and this creates variability in glucose levels and insulin requirements and increases the frequency of hypo- and hyperglycemia. The factors that influence insulin sensitivity are complex and include inhibition of tyrosine kinase activity of the beta subunit, increased proteolytic activity resulting in loss of receptors from the plasma membrane, and possibly the transfer of insulin receptors into the nucleus where they bind to gene promoters. Better understanding of the role of insulin in critically ill patients requires prospective studies measuring insulin levels in various patient groups and the development of a simple measure of insulin sensitivity." @default.
- W3099832882 created "2020-11-23" @default.
- W3099832882 creator A5022411275 @default.
- W3099832882 creator A5065216443 @default.
- W3099832882 date "2021-03-01" @default.
- W3099832882 modified "2023-10-14" @default.
- W3099832882 title "Hyperglycemia, Insulin, and Insulin Resistance in Sepsis" @default.
- W3099832882 cites W1641984158 @default.
- W3099832882 cites W1976181767 @default.
- W3099832882 cites W1980717583 @default.
- W3099832882 cites W1990325541 @default.
- W3099832882 cites W1992073926 @default.
- W3099832882 cites W1997146974 @default.
- W3099832882 cites W2014846814 @default.
- W3099832882 cites W2038562613 @default.
- W3099832882 cites W2049975954 @default.
- W3099832882 cites W2060454917 @default.
- W3099832882 cites W2063944571 @default.
- W3099832882 cites W2072641917 @default.
- W3099832882 cites W2077156459 @default.
- W3099832882 cites W2082857916 @default.
- W3099832882 cites W2088180294 @default.
- W3099832882 cites W2097202487 @default.
- W3099832882 cites W2101510325 @default.
- W3099832882 cites W2112413374 @default.
- W3099832882 cites W2113343489 @default.
- W3099832882 cites W2122484371 @default.
- W3099832882 cites W2124938354 @default.
- W3099832882 cites W2125163474 @default.
- W3099832882 cites W2134644322 @default.
- W3099832882 cites W2138568234 @default.
- W3099832882 cites W2139871065 @default.
- W3099832882 cites W2145053281 @default.
- W3099832882 cites W2157775267 @default.
- W3099832882 cites W2162877252 @default.
- W3099832882 cites W2163865411 @default.
- W3099832882 cites W2171831692 @default.
- W3099832882 cites W2274156819 @default.
- W3099832882 cites W2279086277 @default.
- W3099832882 cites W2295634666 @default.
- W3099832882 cites W2560849741 @default.
- W3099832882 cites W2594222251 @default.
- W3099832882 cites W2753694826 @default.
- W3099832882 cites W2883107039 @default.
- W3099832882 cites W2897277000 @default.
- W3099832882 cites W2929623625 @default.
- W3099832882 cites W2979643002 @default.
- W3099832882 doi "https://doi.org/10.1016/j.amjms.2020.11.007" @default.
- W3099832882 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/33500122" @default.
- W3099832882 hasPublicationYear "2021" @default.
- W3099832882 type Work @default.
- W3099832882 sameAs 3099832882 @default.
- W3099832882 citedByCount "13" @default.
- W3099832882 countsByYear W30998328822021 @default.
- W3099832882 countsByYear W30998328822022 @default.
- W3099832882 countsByYear W30998328822023 @default.
- W3099832882 crossrefType "journal-article" @default.
- W3099832882 hasAuthorship W3099832882A5022411275 @default.
- W3099832882 hasAuthorship W3099832882A5065216443 @default.
- W3099832882 hasConcept C1008401 @default.
- W3099832882 hasConcept C112446052 @default.
- W3099832882 hasConcept C126322002 @default.
- W3099832882 hasConcept C134018914 @default.
- W3099832882 hasConcept C185967709 @default.
- W3099832882 hasConcept C2777391703 @default.
- W3099832882 hasConcept C2778384902 @default.
- W3099832882 hasConcept C2779306644 @default.
- W3099832882 hasConcept C71315377 @default.
- W3099832882 hasConcept C71924100 @default.
- W3099832882 hasConceptScore W3099832882C1008401 @default.
- W3099832882 hasConceptScore W3099832882C112446052 @default.
- W3099832882 hasConceptScore W3099832882C126322002 @default.
- W3099832882 hasConceptScore W3099832882C134018914 @default.
- W3099832882 hasConceptScore W3099832882C185967709 @default.
- W3099832882 hasConceptScore W3099832882C2777391703 @default.
- W3099832882 hasConceptScore W3099832882C2778384902 @default.
- W3099832882 hasConceptScore W3099832882C2779306644 @default.
- W3099832882 hasConceptScore W3099832882C71315377 @default.
- W3099832882 hasConceptScore W3099832882C71924100 @default.
- W3099832882 hasIssue "3" @default.
- W3099832882 hasLocation W30998328821 @default.
- W3099832882 hasOpenAccess W3099832882 @default.
- W3099832882 hasPrimaryLocation W30998328821 @default.
- W3099832882 hasRelatedWork W138803513 @default.
- W3099832882 hasRelatedWork W1986132654 @default.
- W3099832882 hasRelatedWork W2010140898 @default.
- W3099832882 hasRelatedWork W2021423368 @default.
- W3099832882 hasRelatedWork W2082140668 @default.
- W3099832882 hasRelatedWork W2098842401 @default.
- W3099832882 hasRelatedWork W2135403984 @default.
- W3099832882 hasRelatedWork W2150233632 @default.
- W3099832882 hasRelatedWork W2197098620 @default.
- W3099832882 hasRelatedWork W4234612679 @default.
- W3099832882 hasVolume "361" @default.
- W3099832882 isParatext "false" @default.
- W3099832882 isRetracted "false" @default.
- W3099832882 magId "3099832882" @default.
- W3099832882 workType "article" @default.