Matches in SemOpenAlex for { <https://semopenalex.org/work/W3100187538> ?p ?o ?g. }
- W3100187538 endingPage "318" @default.
- W3100187538 startingPage "313" @default.
- W3100187538 abstract "BACKGROUND Cutaneous squamous cell carcinoma (SCC) is the second most common type of skin cancer. Only 2% to 5% of SCCs metastasize; however, those do carry a poor prognosis. Immunohistochemistry (IHC) is widely used by pathologists to characterize skin cancers and provide clinically useful information. OBJECTIVE To evaluate the potential prognostic associations between IHC findings and metastasis in SCC. METHODS Searches were conducted in MEDLINE via PubMed for articles published between 1999 and 2019. Search criteria included key words “immunohistochemistry” and “cutaneous squamous cell carcinoma.” Six hundred and fifty-three articles were returned and screened, which ultimately left 31 for inclusion in our manuscript. RESULTS Thirty-one articles analyzed in this review included a discussion of the expression of a particular IHC marker and the associated risk of metastasis and/or clinical utility of IHC markers in SCC, especially metastatic SCC. Markers that had several or more studies supporting clinical utility were E-cadherin, podoplanin, CD8 + T cells, PD-L1, epidermal growth factor receptor, and Cyclin D1. CONCLUSION Immunohistochemistry profiling of SCC may be useful in select cases when providing a prognosis remains challenging and in identification of potential therapeutic targets for high-risk or metastatic tumors." @default.
- W3100187538 created "2020-11-23" @default.
- W3100187538 creator A5007287153 @default.
- W3100187538 creator A5014830806 @default.
- W3100187538 creator A5015363629 @default.
- W3100187538 creator A5025941380 @default.
- W3100187538 creator A5028968904 @default.
- W3100187538 date "2020-11-03" @default.
- W3100187538 modified "2023-10-02" @default.
- W3100187538 title "The Correlation Between Immunohistochemistry Findings and Metastasis in Squamous Cell Carcinoma" @default.
- W3100187538 cites W1512368430 @default.
- W3100187538 cites W1513172031 @default.
- W3100187538 cites W1520475437 @default.
- W3100187538 cites W1582563291 @default.
- W3100187538 cites W1594237846 @default.
- W3100187538 cites W1964650964 @default.
- W3100187538 cites W1994136786 @default.
- W3100187538 cites W1996291678 @default.
- W3100187538 cites W2003667054 @default.
- W3100187538 cites W2006216648 @default.
- W3100187538 cites W2007356985 @default.
- W3100187538 cites W2010503133 @default.
- W3100187538 cites W2012302921 @default.
- W3100187538 cites W2019461334 @default.
- W3100187538 cites W2022622551 @default.
- W3100187538 cites W2028843540 @default.
- W3100187538 cites W2031868047 @default.
- W3100187538 cites W2039295745 @default.
- W3100187538 cites W2043376395 @default.
- W3100187538 cites W2049274554 @default.
- W3100187538 cites W2050750704 @default.
- W3100187538 cites W2051420169 @default.
- W3100187538 cites W2057268417 @default.
- W3100187538 cites W2089338970 @default.
- W3100187538 cites W2090095735 @default.
- W3100187538 cites W2095483608 @default.
- W3100187538 cites W2101157733 @default.
- W3100187538 cites W2102194474 @default.
- W3100187538 cites W2102929941 @default.
- W3100187538 cites W2108775833 @default.
- W3100187538 cites W2121557104 @default.
- W3100187538 cites W2121664015 @default.
- W3100187538 cites W2125970092 @default.
- W3100187538 cites W2132297395 @default.
- W3100187538 cites W2133223718 @default.
- W3100187538 cites W2146086092 @default.
- W3100187538 cites W2151979638 @default.
- W3100187538 cites W2155835369 @default.
- W3100187538 cites W2155933329 @default.
- W3100187538 cites W2158953656 @default.
- W3100187538 cites W2167811975 @default.
- W3100187538 cites W2168418784 @default.
- W3100187538 cites W2171362247 @default.
- W3100187538 cites W2295766629 @default.
- W3100187538 cites W2303235652 @default.
- W3100187538 cites W2325631775 @default.
- W3100187538 cites W2339226289 @default.
- W3100187538 cites W2346846664 @default.
- W3100187538 cites W2512509856 @default.
- W3100187538 cites W2527438532 @default.
- W3100187538 cites W2527905628 @default.
- W3100187538 cites W2535835299 @default.
- W3100187538 cites W2549108324 @default.
- W3100187538 cites W2554621159 @default.
- W3100187538 cites W2605683323 @default.
- W3100187538 cites W2616751595 @default.
- W3100187538 cites W2736279675 @default.
- W3100187538 cites W2756978353 @default.
- W3100187538 cites W2792512660 @default.
- W3100187538 cites W2795535419 @default.
- W3100187538 cites W2802206159 @default.
- W3100187538 cites W2802323725 @default.
- W3100187538 cites W2805968856 @default.
- W3100187538 cites W2884245553 @default.
- W3100187538 cites W2899968320 @default.
- W3100187538 cites W2905557785 @default.
- W3100187538 cites W2915116582 @default.
- W3100187538 cites W2918928681 @default.
- W3100187538 cites W2918948206 @default.
- W3100187538 cites W2931202609 @default.
- W3100187538 cites W2940153447 @default.
- W3100187538 cites W2952035822 @default.
- W3100187538 cites W2961988991 @default.
- W3100187538 cites W2963394471 @default.
- W3100187538 cites W4205678276 @default.
- W3100187538 cites W4246472220 @default.
- W3100187538 cites W4248518923 @default.
- W3100187538 cites W51995314 @default.
- W3100187538 doi "https://doi.org/10.1097/dss.0000000000002850" @default.
- W3100187538 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/33165065" @default.
- W3100187538 hasPublicationYear "2020" @default.
- W3100187538 type Work @default.
- W3100187538 sameAs 3100187538 @default.
- W3100187538 citedByCount "5" @default.
- W3100187538 countsByYear W31001875382021 @default.
- W3100187538 countsByYear W31001875382022 @default.
- W3100187538 countsByYear W31001875382023 @default.
- W3100187538 crossrefType "journal-article" @default.