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• W3100204637 abstract "Endovenous laser ablation (EVLA), often guided by ultrasound (US) imaging, is a minimally invasive treatment for varicose veins. US artifacts and the absence of a real-time temperature feedback system limits the efficacy of EVLA procedures and causes deep vein and heat induced thrombosis. Our previous phantom and tissue studies have validated the superior features of photoacoustic (PA) imaging in catheter tip tracking and temperature monitoring studies. During EVLA studies, the high temperature inside the vein caused by the CW laser leads to the alteration of the optical absorption properties of blood and water-based tissues and affects PA-based temperature measurements. Hence, by measuring the optical properties of blood and water at high temperatures, these variations can be compensated and can provide quantitative thermometry. The PA thermometry system can by calibrated ex vivo by computing the relationship between the temperature of blood or water and the PA signal at constant pulsed laser energy and can provide quantitative temperature measurements within the veins located at different depths. In this study, we propose to test, validate, and calibrate the developed integrated PAI EVLA system in vivo using a canine model." @default.
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• W3100204637 date "2020-09-07" @default.
• W3100204637 modified "2023-10-12" @default.
• W3100204637 title "Photoacoustic Guided Endovenous Laser Ablation: Calibration and In Vivo Canine Studies" @default.
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• W3100204637 doi "https://doi.org/10.1109/ius46767.2020.9251379" @default.
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