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- W3100206302 abstract "Abstract Dendritic spines, small protrusions of the dendrites, enlarge upon LTP induction, linking morphological and functional properties. Although the role of actin in spine enlargement has been well studied, little is known about its relationship with mechanical membrane properties, such as membrane tension, which is involved in many cell processes, like exocytosis. Here, we use a 3D model of the dendritic spine to investigate how polymerization of actin filaments can effectively elevate the membrane tension to trigger exocytosis in a domain close to the tip of the spine. Moreover, we show that the same pool of actin promotes full membrane fusion after exocytosis and spine stabilization." @default.
- W3100206302 created "2020-11-23" @default.
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- W3100206302 date "2020-11-16" @default.
- W3100206302 modified "2023-10-16" @default.
- W3100206302 title "Exploring new roles for actin upon LTP induction in dendritic spines" @default.
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- W3100206302 doi "https://doi.org/10.1101/2020.11.14.382663" @default.
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