Matches in SemOpenAlex for { <https://semopenalex.org/work/W3100225858> ?p ?o ?g. }
- W3100225858 endingPage "3525" @default.
- W3100225858 startingPage "3519" @default.
- W3100225858 abstract "Azoxy compounds belong to a small group of natural products sharing a common functional group with the general structure RN = N+(O-)R. Three new azoxides, azodyrecins A-C (1-3), were isolated from a soil-derived Streptomyces sp. strain P8-A2. The cis-alkenyl unit in 1-3 was found to readily isomerize to the trans-congeners (4-6). The structures of the new compounds were determined by detailed spectroscopic (1D/2D NMR) and HRMS data analysis. Azodyrecins belong to a new class of natural azoxy compounds and are proposed to derive from l-alanine and alkylamines. The absolute configurations of 1-6 were defined by comparison of ECD spectra. While no antimicrobial effects were observed for 1 against Staphylococcus aureus, Vibrio anguillarum, or Candida albicans, azodyrecin B (2) exhibited cytotoxicity against the human leukemia cell line HL-60 with an IC50 value of 2.2 μM." @default.
- W3100225858 created "2020-11-23" @default.
- W3100225858 creator A5015192553 @default.
- W3100225858 creator A5035163177 @default.
- W3100225858 creator A5044364019 @default.
- W3100225858 creator A5061787967 @default.
- W3100225858 creator A5061953998 @default.
- W3100225858 creator A5069738943 @default.
- W3100225858 creator A5078710856 @default.
- W3100225858 date "2020-11-20" @default.
- W3100225858 modified "2023-10-02" @default.
- W3100225858 title "Azodyrecins A–C: Azoxides from a Soil-Derived <i>Streptomyces</i> Species" @default.
- W3100225858 cites W1514477684 @default.
- W3100225858 cites W1978227254 @default.
- W3100225858 cites W1982795678 @default.
- W3100225858 cites W1987799594 @default.
- W3100225858 cites W1997356306 @default.
- W3100225858 cites W1998350798 @default.
- W3100225858 cites W2009410432 @default.
- W3100225858 cites W2013254853 @default.
- W3100225858 cites W2015037514 @default.
- W3100225858 cites W2030035423 @default.
- W3100225858 cites W2035942327 @default.
- W3100225858 cites W2039529614 @default.
- W3100225858 cites W2044887610 @default.
- W3100225858 cites W2046604694 @default.
- W3100225858 cites W2049543473 @default.
- W3100225858 cites W2057715041 @default.
- W3100225858 cites W2060657382 @default.
- W3100225858 cites W2074509460 @default.
- W3100225858 cites W2078297589 @default.
- W3100225858 cites W2083682970 @default.
- W3100225858 cites W2084255987 @default.
- W3100225858 cites W2089535298 @default.
- W3100225858 cites W2101878475 @default.
- W3100225858 cites W2105535304 @default.
- W3100225858 cites W2127506846 @default.
- W3100225858 cites W2127909293 @default.
- W3100225858 cites W2152898593 @default.
- W3100225858 cites W2194578583 @default.
- W3100225858 cites W2318324030 @default.
- W3100225858 cites W2325916148 @default.
- W3100225858 cites W2327887113 @default.
- W3100225858 cites W2333489179 @default.
- W3100225858 cites W2399480785 @default.
- W3100225858 cites W2404250885 @default.
- W3100225858 cites W2778820641 @default.
- W3100225858 cites W2947940995 @default.
- W3100225858 cites W2950864882 @default.
- W3100225858 cites W2952351488 @default.
- W3100225858 cites W2979308952 @default.
- W3100225858 doi "https://doi.org/10.1021/acs.jnatprod.0c00339" @default.
- W3100225858 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/33216557" @default.
- W3100225858 hasPublicationYear "2020" @default.
- W3100225858 type Work @default.
- W3100225858 sameAs 3100225858 @default.
- W3100225858 citedByCount "9" @default.
- W3100225858 countsByYear W31002258582022 @default.
- W3100225858 countsByYear W31002258582023 @default.
- W3100225858 crossrefType "journal-article" @default.
- W3100225858 hasAuthorship W3100225858A5015192553 @default.
- W3100225858 hasAuthorship W3100225858A5035163177 @default.
- W3100225858 hasAuthorship W3100225858A5044364019 @default.
- W3100225858 hasAuthorship W3100225858A5061787967 @default.
- W3100225858 hasAuthorship W3100225858A5061953998 @default.
- W3100225858 hasAuthorship W3100225858A5069738943 @default.
- W3100225858 hasAuthorship W3100225858A5078710856 @default.
- W3100225858 hasBestOaLocation W31002258582 @default.
- W3100225858 hasConcept C105702510 @default.
- W3100225858 hasConcept C109316439 @default.
- W3100225858 hasConcept C178790620 @default.
- W3100225858 hasConcept C185592680 @default.
- W3100225858 hasConcept C202751555 @default.
- W3100225858 hasConcept C2776154503 @default.
- W3100225858 hasConcept C2776683811 @default.
- W3100225858 hasConcept C2778022156 @default.
- W3100225858 hasConcept C2778803632 @default.
- W3100225858 hasConcept C2779489039 @default.
- W3100225858 hasConcept C2779920670 @default.
- W3100225858 hasConcept C2780917455 @default.
- W3100225858 hasConcept C2781348184 @default.
- W3100225858 hasConcept C4937899 @default.
- W3100225858 hasConcept C523546767 @default.
- W3100225858 hasConcept C54355233 @default.
- W3100225858 hasConcept C55493867 @default.
- W3100225858 hasConcept C71240020 @default.
- W3100225858 hasConcept C86803240 @default.
- W3100225858 hasConcept C89423630 @default.
- W3100225858 hasConceptScore W3100225858C105702510 @default.
- W3100225858 hasConceptScore W3100225858C109316439 @default.
- W3100225858 hasConceptScore W3100225858C178790620 @default.
- W3100225858 hasConceptScore W3100225858C185592680 @default.
- W3100225858 hasConceptScore W3100225858C202751555 @default.
- W3100225858 hasConceptScore W3100225858C2776154503 @default.
- W3100225858 hasConceptScore W3100225858C2776683811 @default.
- W3100225858 hasConceptScore W3100225858C2778022156 @default.
- W3100225858 hasConceptScore W3100225858C2778803632 @default.
- W3100225858 hasConceptScore W3100225858C2779489039 @default.