FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W3100253875> ?p ?o ?g. }

• W3100253875 endingPage "2723" @default.
• W3100253875 startingPage "2723" @default.
• W3100253875 abstract "This study introduces a new synthesis route for obtaining homogeneous chitosan (CS)-silica hybrid aerogels with CS contents up to 10 wt%, using 3-glycidoxypropyl trimethoxysilane (GPTMS) as coupling agent, for tissue engineering applications. Aerogels were obtained using the sol-gel process followed by CO2 supercritical drying, resulting in samples with bulk densities ranging from 0.17 g/cm3 to 0.38 g/cm3. The textural analysis by N2-physisorption revealed an interconnected mesopore network with decreasing specific surface areas (1230-700 m2/g) and pore sizes (11.1-8.7 nm) by increasing GPTMS content (2-4 molar ratio GPTMS:CS monomer). In addition, samples exhibited extremely fast swelling by spontaneous capillary imbibition in PBS solution, presenting swelling capacities from 1.75 to 3.75. The formation of a covalent crosslinked hybrid structure was suggested by FTIR and confirmed by an increase of four hundred fold or more in the compressive strength up to 96 MPa. Instead, samples synthesized without GPTMS fractured at only 0.10-0.26 MPa, revealing a week structure consisted in interpenetrated polymer networks. The aerogels presented bioactivity in simulated body fluid (SBF), as confirmed by the in vitro formation of hydroxyapatite (HAp) layer with crystal size of approximately 2 µm size in diameter. In vitro studies revealed also non cytotoxic effect on HOB® osteoblasts and also a mechanosensitive response. Additionally, control cells grown on glass developed scarce or no stress fibers, while cells grown on hybrid samples showed a significant (p < 0.05) increase in well-developed stress fibers and mature focal adhesion complexes." @default.
• W3100253875 created "2020-11-23" @default.
• W3100253875 creator A5005484454 @default.
• W3100253875 creator A5017332586 @default.
• W3100253875 creator A5019112513 @default.
• W3100253875 creator A5041970278 @default.
• W3100253875 creator A5045530122 @default.
• W3100253875 creator A5057981727 @default.
• W3100253875 creator A5059020572 @default.
• W3100253875 creator A5061586317 @default.
• W3100253875 creator A5072805496 @default.
• W3100253875 creator A5083441505 @default.
• W3100253875 date "2020-11-17" @default.
• W3100253875 modified "2023-10-18" @default.
• W3100253875 title "Chitosan-GPTMS-Silica Hybrid Mesoporous Aerogels for Bone Tissue Engineering" @default.
• W3100253875 cites W1012365194 @default.
• W3100253875 cites W1915689058 @default.
• W3100253875 cites W1920566393 @default.
• W3100253875 cites W1968832304 @default.
• W3100253875 cites W1977134742 @default.
• W3100253875 cites W1986423931 @default.
• W3100253875 cites W1993006648 @default.
• W3100253875 cites W1998496461 @default.
• W3100253875 cites W2001852846 @default.
• W3100253875 cites W2008480020 @default.
• W3100253875 cites W2010142131 @default.
• W3100253875 cites W2010481935 @default.
• W3100253875 cites W2012248021 @default.
• W3100253875 cites W2012667576 @default.
• W3100253875 cites W2015672013 @default.
• W3100253875 cites W2023722900 @default.
• W3100253875 cites W2025262129 @default.
• W3100253875 cites W2026148162 @default.
• W3100253875 cites W2036912612 @default.
• W3100253875 cites W2042210454 @default.
• W3100253875 cites W2047021817 @default.
• W3100253875 cites W2047434407 @default.
• W3100253875 cites W2054769971 @default.
• W3100253875 cites W2061997282 @default.
• W3100253875 cites W2062329090 @default.
• W3100253875 cites W2063710552 @default.
• W3100253875 cites W2069573714 @default.
• W3100253875 cites W2079595896 @default.
• W3100253875 cites W2086514756 @default.
• W3100253875 cites W2086699454 @default.
• W3100253875 cites W2086854047 @default.
• W3100253875 cites W2094321133 @default.
• W3100253875 cites W2098726199 @default.
• W3100253875 cites W2104324964 @default.
• W3100253875 cites W2105960546 @default.
• W3100253875 cites W2113379255 @default.
• W3100253875 cites W2131980222 @default.
• W3100253875 cites W2147825894 @default.
• W3100253875 cites W2148454908 @default.
• W3100253875 cites W2153514139 @default.
• W3100253875 cites W2153994598 @default.
• W3100253875 cites W2162406511 @default.
• W3100253875 cites W2163884408 @default.
• W3100253875 cites W2292035093 @default.
• W3100253875 cites W2320424785 @default.
• W3100253875 cites W2326648613 @default.
• W3100253875 cites W2414545839 @default.
• W3100253875 cites W2495074072 @default.
• W3100253875 cites W2512531492 @default.
• W3100253875 cites W2514307204 @default.
• W3100253875 cites W2523751556 @default.
• W3100253875 cites W2611588166 @default.
• W3100253875 cites W2755181044 @default.
• W3100253875 cites W2755845751 @default.
• W3100253875 cites W2775388813 @default.
• W3100253875 cites W2804188387 @default.
• W3100253875 cites W2893539219 @default.
• W3100253875 cites W2899404609 @default.
• W3100253875 cites W2908964290 @default.
• W3100253875 cites W2921560047 @default.
• W3100253875 cites W2922378844 @default.
• W3100253875 cites W2944272002 @default.
• W3100253875 cites W2969596545 @default.
• W3100253875 cites W2988773419 @default.
• W3100253875 cites W3014702865 @default.
• W3100253875 cites W3024036410 @default.
• W3100253875 cites W3034621010 @default.
• W3100253875 cites W843007777 @default.
• W3100253875 doi "https://doi.org/10.3390/polym12112723" @default.
• W3100253875 hasPubMedCentralId "https://www.ncbi.nlm.nih.gov/pmc/articles/7698430" @default.
• W3100253875 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/33212958" @default.
• W3100253875 hasPublicationYear "2020" @default.
• W3100253875 type Work @default.
• W3100253875 sameAs 3100253875 @default.
• W3100253875 citedByCount "20" @default.
• W3100253875 countsByYear W31002538752021 @default.
• W3100253875 countsByYear W31002538752022 @default.
• W3100253875 countsByYear W31002538752023 @default.
• W3100253875 crossrefType "journal-article" @default.
• W3100253875 hasAuthorship W3100253875A5005484454 @default.
• W3100253875 hasAuthorship W3100253875A5017332586 @default.
• W3100253875 hasAuthorship W3100253875A5019112513 @default.
• W3100253875 hasAuthorship W3100253875A5041970278 @default.

• next