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• W3100293432 startingPage "102202" @default.
• W3100293432 abstract "Nowadays, biogenic synthesis of metal nanoparticles using plants has attracted greater in a wide range of pharmaceutical interest owing to posses suitable alternative treatment strategies than existing conventional chemical methods. In the present study, we reported the facile, cost-effective, reproducible biogenic synthesis of silver nanoparticles (Gp-AgNPs) using Indian folk medicinal plant, Gnaphalium polycaulon (Gp) leaves extract. The formation of Gp-AgNPs was confirmed by the assistance of different sophisticated analytical techniques. The synthesized Gp-AgNPs exhibited the maximum SPR peak at 365 nm. FT-IR result indicated the presence of various active functional groups in the extract, which may be responsible for the reduction and stabilization of the Gp-AgNPs. The spherical and triangle shapes with <50 nm size of Gp-AgNPs were authorized by SEM and HR-TEM analyses. The Gp-AgNPs exhibited superior antimicrobial activity against selective Gram-positive ( Staphylococcus aureus ), Gram-negative ( Escherichia coli ) bacterial, and fungal ( Candida albicans ) pathogens. The synthesized Gp-AgNPs suppressed the growth of most dreadful pathogens associated with wound infection. The efficiency of Gp-AgNPs on fastening the rate of healing of a wound was confirmed by in vivo studies. in vitro drug-releasing activity was determined by in vitro dialysis bag method. Concomitantly, the current study is the first attempt to exemplify the potent broad-spectrum of antimicrobial and wound healing efficacies of Gp-AgNPs from G. polycaulon , which could plausibly be a promising biomaterial for various biomedical applications. • AgNPs was synthesized using G. polycaulon plant leaves. • The synthesized Gp-AgNPs have good antibacterial activity. • Gp-AgNPs showed remarkable wound healing activity and drug delivery." @default.
• W3100293432 created "2020-11-23" @default.
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• W3100293432 date "2021-02-01" @default.
• W3100293432 modified "2023-10-17" @default.
• W3100293432 title "An eco-friendly Gnaphalium polycaulon mediated silver nanoparticles: Synthesis, characterization, antimicrobial, wound healing and drug release studies" @default.
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• W3100293432 doi "https://doi.org/10.1016/j.jddst.2020.102202" @default.
• W3100293432 hasPublicationYear "2021" @default.
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