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- W3100336757 abstract "Although numerous trials have convincingly shown benefits of statin therapy in both primary and secondary prevention of atherosclerotic cardiovascular disease (ASCVD), most showed relative risk reductions of 25-40%, and thus many individuals continue to have ASCVD events despite statin therapy. Substantial progress has been made in developing therapies that address the residual risk for ASCVD despite statin therapy. In this review, we summarize progress of currently available therapies along with therapies under development that further reduce low-density lipoprotein cholesterol and apolipoprotein B-containing lipoproteins, reduce lipoprotein(a), reduce ASCVD events in patients with high triglycerides, and directly target inflammation to reduce ASCVD risk." @default.
- W3100336757 created "2020-11-23" @default.
- W3100336757 creator A5044898000 @default.
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- W3100336757 date "2021-01-27" @default.
- W3100336757 modified "2023-10-09" @default.
- W3100336757 title "New Approaches for the Prevention and Treatment of Cardiovascular Disease: Focus on Lipoproteins and Inflammation" @default.
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- W3100336757 doi "https://doi.org/10.1146/annurev-med-100119-013612" @default.
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