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- W3100361750 abstract "Very early in the history of mining and with the industrial applications of asbestos, it was known that a variety of mineral fibers were hazardous to health. By the 1940s, the potential risk of lung cancer, in addition to the fibrosis disorder asbestosis, one of the pneumoconioses, was described. Within twenty years, another malignant disease, mesothelioma, cancer of the tissues that surround the lung, was ascribed to asbestos exposure. It is now common knowledge that inhalation of certain mineral fibers can cause disease (Skinner et al. 1988). Because the fibers are inhaled, the lung and surrounding tissues are the primary targets, but there may be subsequent reactions in many other parts of the body. The information on disease related to fibrous materials emanates from studies of occupational environments where the dose or exposure is likely to be high and continued over long periods of time. However, it has been increasingly realized that domestic or general environmental exposure is also possible and can pose grave dangers. For a mineral fiber to be inhalable it should be less than one micron in diameter, but the length can be 10 microns or greater because the particle can align with the air stream in the bronchi and penetrate far into the lung. The ratio between length and diameter of the fiber is critical. The most dangerous fibers are very thin (one tenth of a micron in diameter or less) with a high length-diameter ratio. Another important factor is biodurability. Typically, the dangerous fibers are not broken down at all or only very slowly, with half-lives in the body of many years. They may remain in situ throughout life and can be found at autopsy. There are many varieties of fibers in the environment today, both naturally occurring and man-made. Only a few, however, fulfill the above criteria and occur in amounts where human exposure is possible. The problem fibers are collectively known as asbestos and the fibrous zeolite, erionite. There are many other fibers (Skinner et al. 1988), but their contributions to human disease are not recognized. Asbestos is not a mineralogical but a commercial term." @default.
- W3100361750 created "2020-11-23" @default.
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- W3100361750 date "2003-04-10" @default.
- W3100361750 modified "2023-10-14" @default.
- W3100361750 title "Health Problems Related to Environmental Fibrous Minerals" @default.
- W3100361750 doi "https://doi.org/10.1093/oso/9780195162042.003.0025" @default.
- W3100361750 hasPublicationYear "2003" @default.
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