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- W3100402641 abstract "We study theoretically the mechanical failure of a simple model of double-stranded DNA under an applied shear. Starting from a more microscopic Hamiltonian that describes a sheared DNA, we arrive at a nonlinear generalization of a ladder model of shear unzipping proposed earlier by deGennes [de Gennes, P. G. C. R. Acad. Sci., Ser. IV: Phys., Astrophys. 2001, 1505]. Using this model and a combination of analytical and numerical methods, we study the DNA unzipping transition when the shearing force exceeds a critical threshold at zero temperature. We also explore the effects of sequence heterogeneity and finite temperature and discuss possible applications to determine the strength of colloidal nanoparticle assemblies functionalized by DNA." @default.
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- W3100402641 date "2009-01-15" @default.
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- W3100402641 title "Shear Unzipping of DNA" @default.
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- W3100402641 doi "https://doi.org/10.1021/jp808232p" @default.
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