FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W3100425716> ?p ?o ?g. }

• W3100425716 endingPage "2653" @default.
• W3100425716 startingPage "2653" @default.
• W3100425716 abstract "A wide range of naturally derived and synthetic biodegradable and biocompatible polymers are today regarded as promising materials for improving skin regeneration. Alongside this, these materials have been explored in conjunction with different types of antimicrobial and bioactive agents, especially natural-derived compounds, to enhance their biological properties. Herein, a double-layered nanocomposite dressing membrane was fabricated with two distinct layers. A bottom layer from Chitosan-Sodium tripolyphosphate (CS-TPP) and Poly(vinyl alcohol) (PVA) containing Centella asiatica (L.) (CA) was electrospun directly over a Polycaprolactone (PCL) layer to improve the biologic performance of the electrospun nanofibers. In turn, the PCL layer was designed to provide mechanical support to the damaged tissue. The results revealed that the produced double-layered nanocomposite membrane closely resembles the mechanical, porosity, and wettability features required for skin tissue engineering. On the other hand, the in vitro drug release profile of the PCL/PVA_CS-TPP containing CA exhibited a controlled release for 10 days. Moreover, the PVA_CS-TPP_CA's bottom layer displayed the highest antibacterial activity against Staphylococcus aureus (S. aureus) (99.96 ± 6.04%) and Pseudomonas aeruginosa (P. aeruginosa) (99.94 ± 0.67%), which is responsible for avoiding bacterial penetration while endowing bioactive properties. Finally, the 3-(4,5-Dimethyl-2-thiazolyl)-2,5-diphenyl-2H-tetrazolium bromide (MTT) assay showed that this nanocomposite membrane was not cytotoxic for normal human dermal fibroblasts (NHDF) cells. Therefore, these findings suggest the potential use of the double-layered PCL/PVA_CS-TPP_CA as an efficient bionanocomposite dressing material." @default.
• W3100425716 created "2020-11-23" @default.
• W3100425716 creator A5028402265 @default.
• W3100425716 creator A5043737288 @default.
• W3100425716 creator A5048162501 @default.
• W3100425716 date "2020-11-11" @default.
• W3100425716 modified "2023-10-17" @default.
• W3100425716 title "Preparation and Characterization of Electrospun Double-layered Nanocomposites Membranes as a Carrier for Centella asiatica (L.)" @default.
• W3100425716 cites W1503737910 @default.
• W3100425716 cites W1803766817 @default.
• W3100425716 cites W1971465266 @default.
• W3100425716 cites W2007584755 @default.
• W3100425716 cites W2008634982 @default.
• W3100425716 cites W2074065611 @default.
• W3100425716 cites W2100081636 @default.
• W3100425716 cites W2105698780 @default.
• W3100425716 cites W2110541415 @default.
• W3100425716 cites W2137637704 @default.
• W3100425716 cites W2152404602 @default.
• W3100425716 cites W2167244495 @default.
• W3100425716 cites W2242924843 @default.
• W3100425716 cites W2298630361 @default.
• W3100425716 cites W2315880356 @default.
• W3100425716 cites W2435741365 @default.
• W3100425716 cites W2472193354 @default.
• W3100425716 cites W2487966588 @default.
• W3100425716 cites W2573509740 @default.
• W3100425716 cites W2588354292 @default.
• W3100425716 cites W2589979933 @default.
• W3100425716 cites W2590336671 @default.
• W3100425716 cites W2593643061 @default.
• W3100425716 cites W2602229030 @default.
• W3100425716 cites W2605240696 @default.
• W3100425716 cites W2614933640 @default.
• W3100425716 cites W2757615240 @default.
• W3100425716 cites W2780303757 @default.
• W3100425716 cites W2786823006 @default.
• W3100425716 cites W2790567141 @default.
• W3100425716 cites W2802993494 @default.
• W3100425716 cites W2805873160 @default.
• W3100425716 cites W2886784946 @default.
• W3100425716 cites W2887208360 @default.
• W3100425716 cites W2888861542 @default.
• W3100425716 cites W2899681064 @default.
• W3100425716 cites W2902723191 @default.
• W3100425716 cites W2926918021 @default.
• W3100425716 cites W2950151274 @default.
• W3100425716 cites W2954407453 @default.
• W3100425716 cites W2955027989 @default.
• W3100425716 cites W2968441064 @default.
• W3100425716 cites W2970560762 @default.
• W3100425716 cites W2978871756 @default.
• W3100425716 cites W2980129031 @default.
• W3100425716 cites W2991652072 @default.
• W3100425716 cites W3008157434 @default.
• W3100425716 cites W3019232442 @default.
• W3100425716 cites W3021329269 @default.
• W3100425716 cites W3023944335 @default.
• W3100425716 cites W3045248938 @default.
• W3100425716 cites W3051587176 @default.
• W3100425716 cites W3083527999 @default.
• W3100425716 cites W3092392582 @default.
• W3100425716 cites W3094099018 @default.
• W3100425716 cites W3094418210 @default.
• W3100425716 cites W3096021701 @default.
• W3100425716 cites W4246446186 @default.
• W3100425716 doi "https://doi.org/10.3390/polym12112653" @default.
• W3100425716 hasPubMedCentralId "https://www.ncbi.nlm.nih.gov/pmc/articles/7698172" @default.
• W3100425716 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/33187121" @default.
• W3100425716 hasPublicationYear "2020" @default.
• W3100425716 type Work @default.
• W3100425716 sameAs 3100425716 @default.
• W3100425716 citedByCount "16" @default.
• W3100425716 countsByYear W31004257162020 @default.
• W3100425716 countsByYear W31004257162021 @default.
• W3100425716 countsByYear W31004257162022 @default.
• W3100425716 countsByYear W31004257162023 @default.
• W3100425716 crossrefType "journal-article" @default.
• W3100425716 hasAuthorship W3100425716A5028402265 @default.
• W3100425716 hasAuthorship W3100425716A5043737288 @default.
• W3100425716 hasAuthorship W3100425716A5048162501 @default.
• W3100425716 hasBestOaLocation W31004257161 @default.
• W3100425716 hasConcept C127413603 @default.
• W3100425716 hasConcept C13965031 @default.
• W3100425716 hasConcept C144027150 @default.
• W3100425716 hasConcept C144796933 @default.
• W3100425716 hasConcept C159985019 @default.
• W3100425716 hasConcept C171250308 @default.
• W3100425716 hasConcept C178790620 @default.
• W3100425716 hasConcept C185592680 @default.
• W3100425716 hasConcept C191897082 @default.
• W3100425716 hasConcept C192562407 @default.
• W3100425716 hasConcept C2777230088 @default.
• W3100425716 hasConcept C2779077069 @default.
• W3100425716 hasConcept C2779732960 @default.
• W3100425716 hasConcept C2779868350 @default.
• W3100425716 hasConcept C2780666587 @default.
• W3100425716 hasConcept C41625074 @default.

• next