FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W3100454907> ?p ?o ?g. }

• W3100454907 endingPage "e041269" @default.
• W3100454907 startingPage "e041269" @default.
• W3100454907 abstract "Objectives About 11%–30% of individuals with impaired fasting plasma glucose (IFG) have type 2 diabetes mellitus (T2DM), diagnosed by the 75 g oral glucose tolerance test (75 g OGTT). This study investigated (1) the prevalence and cut-off levels for fasting plasma glucose (FPG) and glycated haemoglobin A1c (HbA1c) in IFG individuals that most effectively predict the presence of T2DM diagnosed by a 75 g OGTT; (2) the predictors associated with T2DM; and (3) the pathophysiological characteristics of patients with IFG. Materials and methods A single-centre, cross-sectional study was conducted in a primary care setting. A standard 75 g OGTT was performed on 123 subjects with IFG. Their beta-cell function and insulin resistance were calculated through plasma glucose and insulin levels monitored during the 75 g OGTT. Results In the IFG subjects, the prevalence of T2DM using the 2-hour postload plasma glucose (2hPG) criterion was 28.5%. Pre-diabetes and normal glucose metabolism were found in 48.7% and 22.8%, respectively, by 75 g OGTT. An HbA1c level ≥6.0% or FPG ≥5.9 mmol/L were the optimal cut-off thresholds for the prediction of the presence of T2DM. HbA1c had a sensitivity of 76.7% and specificity of 55.7% (95% CI 57.7% to 90.1% and 95% CI 43.3% to 67.6%, respectively), while FPG had a sensitivity of 85.7% and specificity of 23.9% (95% CI 69.7% to 95.2% and 95% CI 15.4% to 34.1%, respectively). The presence of metabolic syndrome, a higher HbA1c and higher FPG levels were associated with the risk of T2DM in the Thai IFG population. Conclusions Almost one-third of the people with IFG had T2DM diagnosed by the 2hPG criterion. HbA1c was more effective than FPG in predicting the presence of T2DM in the IFG subjects. IFG individuals with HbA1c≥6.0% or FPG≥5.9 mmol/L should be advised to undergo a 75 g OGTT to detect T2DM earlier than otherwise." @default.
• W3100454907 created "2020-11-23" @default.
• W3100454907 creator A5076233027 @default.
• W3100454907 creator A5084848663 @default.
• W3100454907 date "2020-11-01" @default.
• W3100454907 modified "2023-09-27" @default.
• W3100454907 title "Prediction of type 2 diabetes mellitus using fasting plasma glucose and HbA1c levels among individuals with impaired fasting plasma glucose: a cross-sectional study in Thailand" @default.
• W3100454907 cites W1535007827 @default.
• W3100454907 cites W1583276112 @default.
• W3100454907 cites W2011470760 @default.
• W3100454907 cites W2024508393 @default.
• W3100454907 cites W2052773925 @default.
• W3100454907 cites W2073487154 @default.
• W3100454907 cites W2087525722 @default.
• W3100454907 cites W2095645712 @default.
• W3100454907 cites W2108321760 @default.
• W3100454907 cites W2109124852 @default.
• W3100454907 cites W2109356083 @default.
• W3100454907 cites W2128249041 @default.
• W3100454907 cites W2131377217 @default.
• W3100454907 cites W2143104968 @default.
• W3100454907 cites W2156121263 @default.
• W3100454907 cites W2158822657 @default.
• W3100454907 cites W2160234571 @default.
• W3100454907 cites W2189073781 @default.
• W3100454907 cites W2237874750 @default.
• W3100454907 cites W2337454357 @default.
• W3100454907 cites W2766199104 @default.
• W3100454907 cites W2769264260 @default.
• W3100454907 cites W2773530302 @default.
• W3100454907 cites W2885100166 @default.
• W3100454907 cites W2900926134 @default.
• W3100454907 cites W4236673002 @default.
• W3100454907 cites W4238251256 @default.
• W3100454907 cites W4240986128 @default.
• W3100454907 cites W43176987 @default.
• W3100454907 doi "https://doi.org/10.1136/bmjopen-2020-041269" @default.
• W3100454907 hasPubMedCentralId "https://www.ncbi.nlm.nih.gov/pmc/articles/7656954" @default.
• W3100454907 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/33172945" @default.
• W3100454907 hasPublicationYear "2020" @default.
• W3100454907 type Work @default.
• W3100454907 sameAs 3100454907 @default.
• W3100454907 citedByCount "3" @default.
• W3100454907 countsByYear W31004549072021 @default.
• W3100454907 countsByYear W31004549072022 @default.
• W3100454907 crossrefType "journal-article" @default.
• W3100454907 hasAuthorship W3100454907A5076233027 @default.
• W3100454907 hasAuthorship W3100454907A5084848663 @default.
• W3100454907 hasBestOaLocation W31004549071 @default.
• W3100454907 hasConcept C126322002 @default.
• W3100454907 hasConcept C134018914 @default.
• W3100454907 hasConcept C142052008 @default.
• W3100454907 hasConcept C142724271 @default.
• W3100454907 hasConcept C2777180221 @default.
• W3100454907 hasConcept C2777185836 @default.
• W3100454907 hasConcept C2777391703 @default.
• W3100454907 hasConcept C2780609358 @default.
• W3100454907 hasConcept C2780833929 @default.
• W3100454907 hasConcept C2909938374 @default.
• W3100454907 hasConcept C2910068830 @default.
• W3100454907 hasConcept C3020574416 @default.
• W3100454907 hasConcept C555293320 @default.
• W3100454907 hasConcept C71924100 @default.
• W3100454907 hasConceptScore W3100454907C126322002 @default.
• W3100454907 hasConceptScore W3100454907C134018914 @default.
• W3100454907 hasConceptScore W3100454907C142052008 @default.
• W3100454907 hasConceptScore W3100454907C142724271 @default.
• W3100454907 hasConceptScore W3100454907C2777180221 @default.
• W3100454907 hasConceptScore W3100454907C2777185836 @default.
• W3100454907 hasConceptScore W3100454907C2777391703 @default.
• W3100454907 hasConceptScore W3100454907C2780609358 @default.
• W3100454907 hasConceptScore W3100454907C2780833929 @default.
• W3100454907 hasConceptScore W3100454907C2909938374 @default.
• W3100454907 hasConceptScore W3100454907C2910068830 @default.
• W3100454907 hasConceptScore W3100454907C3020574416 @default.
• W3100454907 hasConceptScore W3100454907C555293320 @default.
• W3100454907 hasConceptScore W3100454907C71924100 @default.
• W3100454907 hasIssue "11" @default.
• W3100454907 hasLocation W31004549071 @default.
• W3100454907 hasOpenAccess W3100454907 @default.
• W3100454907 hasPrimaryLocation W31004549071 @default.
• W3100454907 hasRelatedWork W1955614201 @default.
• W3100454907 hasRelatedWork W1967275117 @default.
• W3100454907 hasRelatedWork W1981633325 @default.
• W3100454907 hasRelatedWork W2003439778 @default.
• W3100454907 hasRelatedWork W2043419594 @default.
• W3100454907 hasRelatedWork W2057655956 @default.
• W3100454907 hasRelatedWork W2116657465 @default.
• W3100454907 hasRelatedWork W2365081170 @default.
• W3100454907 hasRelatedWork W2375979269 @default.
• W3100454907 hasRelatedWork W3100454907 @default.
• W3100454907 hasVolume "10" @default.
• W3100454907 isParatext "false" @default.
• W3100454907 isRetracted "false" @default.
• W3100454907 magId "3100454907" @default.
• W3100454907 workType "article" @default.