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- W3100471102 abstract "Abstract Coronavirus disease 2019 (COVID-19), caused by an infection with the novel coronavirus SARS-CoV-2, has resulted in a global pandemic and poses an emergency to public health systems worldwide. COVID-19 is highly infectious and is characterized by an acute respiratory illness that varies from mild flu-like symptoms to the life-threatening acute respiratory distress syndrome (ARDS). As such, there is an urgent need for the development of new therapeutic strategies, which combat the high mortality in severely ill COVID-19 patients. Glucocorticoids are a frontline treatment for a diverse range of inflammatory diseases. Due to their immunosuppressive functions, the use of glucocorticoids in the treatment of COVID-19 patients was initially regarded with caution. However, recent studies concluded that the initiation of systemic glucocorticoids in patients suffering from severe and critical COVID-19 is associated with lower mortality. Herein we review the anti-inflammatory effects of glucocorticoids and discuss emerging issues in their clinical use in the context of COVID-19." @default.
- W3100471102 created "2020-11-23" @default.
- W3100471102 creator A5004023214 @default.
- W3100471102 creator A5035750809 @default.
- W3100471102 date "2020-11-18" @default.
- W3100471102 modified "2023-10-17" @default.
- W3100471102 title "The Role of Glucocorticoids in the Management of COVID-19" @default.
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- W3100471102 doi "https://doi.org/10.1055/a-1300-2550" @default.
- W3100471102 hasPubMedCentralId "https://www.ncbi.nlm.nih.gov/pmc/articles/7781662" @default.
- W3100471102 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/33207372" @default.
- W3100471102 hasPublicationYear "2020" @default.
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