Matches in SemOpenAlex for { <https://semopenalex.org/work/W3100499177> ?p ?o ?g. }
Showing items 1 to 98 of
98
with 100 items per page.
- W3100499177 endingPage "309" @default.
- W3100499177 startingPage "299" @default.
- W3100499177 abstract "Apolipoprotein E (APOE) is the best-established genetic risk factor for Alzheimer's disease (AD). APOE has a differential relationship with cognition and underlying brain integrity across the lifespan. Younger risk allele (ε4) carriers exhibit higher cognitive performance and greater recruitment of functional brain resources. With aging, ε4 carriers show steeper declines in episodic memory, executive functioning, and perceptual speed compared with ε4 noncarriers. Older ε4 carriers also show more pronounced regional brain atrophy, white matter (WM) disorganization, cerebral hypometabolism, and hallmarks of AD neuropathology. Collectively, the literature demonstrates the need to combine genetic, neuropsychological, and neuroimaging information to identify those who may benefit most from early prevention and treatment efforts, in an effort to reduce the global burden of AD." @default.
- W3100499177 created "2020-11-23" @default.
- W3100499177 creator A5072368891 @default.
- W3100499177 creator A5083965850 @default.
- W3100499177 date "2020-09-02" @default.
- W3100499177 modified "2023-09-25" @default.
- W3100499177 title "APOE as a Risk Factor for Age‐Related Cognitive Impairment" @default.
- W3100499177 cites W1984737558 @default.
- W3100499177 cites W2000658130 @default.
- W3100499177 cites W2005286652 @default.
- W3100499177 cites W2009036027 @default.
- W3100499177 cites W2009339691 @default.
- W3100499177 cites W2010825610 @default.
- W3100499177 cites W2017079501 @default.
- W3100499177 cites W2034250070 @default.
- W3100499177 cites W2041325253 @default.
- W3100499177 cites W2041334242 @default.
- W3100499177 cites W2042885626 @default.
- W3100499177 cites W2050255138 @default.
- W3100499177 cites W2051394059 @default.
- W3100499177 cites W2051489981 @default.
- W3100499177 cites W2062843923 @default.
- W3100499177 cites W2065166923 @default.
- W3100499177 cites W2072348842 @default.
- W3100499177 cites W2078136810 @default.
- W3100499177 cites W2079834962 @default.
- W3100499177 cites W2082190201 @default.
- W3100499177 cites W2087925678 @default.
- W3100499177 cites W2088389101 @default.
- W3100499177 cites W2094768089 @default.
- W3100499177 cites W2102641992 @default.
- W3100499177 cites W2106396500 @default.
- W3100499177 cites W2130008445 @default.
- W3100499177 cites W2135063296 @default.
- W3100499177 cites W2140074909 @default.
- W3100499177 cites W2141346295 @default.
- W3100499177 cites W2145359198 @default.
- W3100499177 cites W2147776113 @default.
- W3100499177 cites W2150177485 @default.
- W3100499177 cites W2152021942 @default.
- W3100499177 cites W2166512828 @default.
- W3100499177 cites W2167872161 @default.
- W3100499177 cites W2172196972 @default.
- W3100499177 cites W4210975612 @default.
- W3100499177 cites W4231652925 @default.
- W3100499177 doi "https://doi.org/10.1002/9781119057840.ch35" @default.
- W3100499177 hasPublicationYear "2020" @default.
- W3100499177 type Work @default.
- W3100499177 sameAs 3100499177 @default.
- W3100499177 citedByCount "0" @default.
- W3100499177 crossrefType "other" @default.
- W3100499177 hasAuthorship W3100499177A5072368891 @default.
- W3100499177 hasAuthorship W3100499177A5083965850 @default.
- W3100499177 hasConcept C126322002 @default.
- W3100499177 hasConcept C14216870 @default.
- W3100499177 hasConcept C15744967 @default.
- W3100499177 hasConcept C169760540 @default.
- W3100499177 hasConcept C169900460 @default.
- W3100499177 hasConcept C2779134260 @default.
- W3100499177 hasConcept C2780130745 @default.
- W3100499177 hasConcept C2781172350 @default.
- W3100499177 hasConcept C50440223 @default.
- W3100499177 hasConcept C57089818 @default.
- W3100499177 hasConcept C58693492 @default.
- W3100499177 hasConcept C71924100 @default.
- W3100499177 hasConcept C88576662 @default.
- W3100499177 hasConceptScore W3100499177C126322002 @default.
- W3100499177 hasConceptScore W3100499177C14216870 @default.
- W3100499177 hasConceptScore W3100499177C15744967 @default.
- W3100499177 hasConceptScore W3100499177C169760540 @default.
- W3100499177 hasConceptScore W3100499177C169900460 @default.
- W3100499177 hasConceptScore W3100499177C2779134260 @default.
- W3100499177 hasConceptScore W3100499177C2780130745 @default.
- W3100499177 hasConceptScore W3100499177C2781172350 @default.
- W3100499177 hasConceptScore W3100499177C50440223 @default.
- W3100499177 hasConceptScore W3100499177C57089818 @default.
- W3100499177 hasConceptScore W3100499177C58693492 @default.
- W3100499177 hasConceptScore W3100499177C71924100 @default.
- W3100499177 hasConceptScore W3100499177C88576662 @default.
- W3100499177 hasLocation W31004991771 @default.
- W3100499177 hasOpenAccess W3100499177 @default.
- W3100499177 hasPrimaryLocation W31004991771 @default.
- W3100499177 hasRelatedWork W2000419411 @default.
- W3100499177 hasRelatedWork W2069084234 @default.
- W3100499177 hasRelatedWork W2087726178 @default.
- W3100499177 hasRelatedWork W2093041092 @default.
- W3100499177 hasRelatedWork W2106304681 @default.
- W3100499177 hasRelatedWork W2466421383 @default.
- W3100499177 hasRelatedWork W2738690256 @default.
- W3100499177 hasRelatedWork W2781541284 @default.
- W3100499177 hasRelatedWork W4233463301 @default.
- W3100499177 hasRelatedWork W4234317510 @default.
- W3100499177 isParatext "false" @default.
- W3100499177 isRetracted "false" @default.
- W3100499177 magId "3100499177" @default.
- W3100499177 workType "other" @default.