Matches in SemOpenAlex for { <https://semopenalex.org/work/W3100578076> ?p ?o ?g. }
- W3100578076 endingPage "104620" @default.
- W3100578076 startingPage "104620" @default.
- W3100578076 abstract "Essential oils and their chemical constituents have been reported with well documented antimicrobial effects against a range of bacterial, fungal and viral pathogens. By definition, essential oils are a complex mixture of volatile organic compounds which are synthesized naturally in different parts of the plant as part of plants secondary metabolism. The chemical composition of the essential oils is dominated by the presence of a range of compounds including phenolics, terpenoids, aldehydes, ketones, ethers, epoxides and many others inferring that essential oils must be effective against a wide range of pathogens. This review article mainly focuses on the antiviral potential of essential oils and their chemical constituents especially against influenza and coronaviruses. Essential oils have been screened against several pathogenic viruses, including influenza and other respiratory viral infections. The essential oils of cinnamon, bergamot, lemongrass, thyme, lavender have been reported to exert potent antiviral effects against influenza type A virus. The essential oil of Citrus reshni leaves has been shown to be effective against H5N1 virus. The essential oil of Lippia species at a concentration of 11.1 μg/mL has been shown to induce 100% inhibition of yellow fever virus in Vero cells. Essential oils and oleoresins have been shown through in vitro and in vivo experiments to induce antiviral effects against Coronavirus infectious bronchitis virus. A study reported 221 phytochemical compounds and essential oils to be effective against severe acute respiratory syndrome associated coronavirus (SARS-CoV) using a cell-based assay measuring SARS-CoV-induced cytopathogenic effect on Vero E6 cells. The main mechanism of antiviral effects of essential oils has been found to cause capsid disintegration and viral expansion which prevents the virus to infect host cells by adsorption via the capsid. Essential oils also inhibit hemagglutinin (an important membrane protein of various viruses) of certain viruses; this membrane protein allows the virus to enter the host cell. Many essential oils and their components could inhibit the late stages of viral life cycle by targeting the redox signalling pathway. Essential oils of Thymus vulgaris, cymbopogon citratus and Rosmarinus officinalis have been found to destabilize the Tat/TAR-RNA complex of HIV-1 virus, this complex being essential for HIV-1 replication. Being lipophilic in nature, essential oils can penetrate viral membranes easily leading to membrane disintegration. The current comprehensive review will facilitate researchers to find chemical entities from plant sources as possible inhibitory agents against various viruses." @default.
- W3100578076 created "2020-11-23" @default.
- W3100578076 creator A5006855988 @default.
- W3100578076 creator A5043190099 @default.
- W3100578076 creator A5056584184 @default.
- W3100578076 creator A5061708190 @default.
- W3100578076 date "2021-03-01" @default.
- W3100578076 modified "2023-10-06" @default.
- W3100578076 title "An updated and comprehensive review of the antiviral potential of essential oils and their chemical constituents with special focus on their mechanism of action against various influenza and coronaviruses" @default.
- W3100578076 cites W1258355370 @default.
- W3100578076 cites W1549839546 @default.
- W3100578076 cites W1557730305 @default.
- W3100578076 cites W1753271690 @default.
- W3100578076 cites W1807697294 @default.
- W3100578076 cites W1964332483 @default.
- W3100578076 cites W1966297990 @default.
- W3100578076 cites W1966575787 @default.
- W3100578076 cites W1968531471 @default.
- W3100578076 cites W1973605014 @default.
- W3100578076 cites W1974329894 @default.
- W3100578076 cites W1978569086 @default.
- W3100578076 cites W1978810017 @default.
- W3100578076 cites W1983919727 @default.
- W3100578076 cites W1986147076 @default.
- W3100578076 cites W1988897041 @default.
- W3100578076 cites W1990331692 @default.
- W3100578076 cites W1991466987 @default.
- W3100578076 cites W1994878012 @default.
- W3100578076 cites W1997692336 @default.
- W3100578076 cites W1998858180 @default.
- W3100578076 cites W1999200503 @default.
- W3100578076 cites W2005034944 @default.
- W3100578076 cites W2008122515 @default.
- W3100578076 cites W2010050723 @default.
- W3100578076 cites W2010717898 @default.
- W3100578076 cites W2011034474 @default.
- W3100578076 cites W2018188418 @default.
- W3100578076 cites W2018689960 @default.
- W3100578076 cites W2020508199 @default.
- W3100578076 cites W2021314445 @default.
- W3100578076 cites W2022292830 @default.
- W3100578076 cites W2025757392 @default.
- W3100578076 cites W2027867097 @default.
- W3100578076 cites W2029021037 @default.
- W3100578076 cites W2029141334 @default.
- W3100578076 cites W2033374941 @default.
- W3100578076 cites W2036163221 @default.
- W3100578076 cites W2036645889 @default.
- W3100578076 cites W2038525852 @default.
- W3100578076 cites W2040909152 @default.
- W3100578076 cites W2043433455 @default.
- W3100578076 cites W2043883593 @default.
- W3100578076 cites W2063771413 @default.
- W3100578076 cites W2066205805 @default.
- W3100578076 cites W2068394433 @default.
- W3100578076 cites W2070895853 @default.
- W3100578076 cites W2078590924 @default.
- W3100578076 cites W2078738566 @default.
- W3100578076 cites W2080798377 @default.
- W3100578076 cites W2081192434 @default.
- W3100578076 cites W2084804447 @default.
- W3100578076 cites W2086525067 @default.
- W3100578076 cites W2087333481 @default.
- W3100578076 cites W2101780807 @default.
- W3100578076 cites W2102380386 @default.
- W3100578076 cites W2102574136 @default.
- W3100578076 cites W2103692482 @default.
- W3100578076 cites W2107337132 @default.
- W3100578076 cites W2108319118 @default.
- W3100578076 cites W2113943110 @default.
- W3100578076 cites W2118689048 @default.
- W3100578076 cites W2122857852 @default.
- W3100578076 cites W2122910156 @default.
- W3100578076 cites W2126891371 @default.
- W3100578076 cites W2127321264 @default.
- W3100578076 cites W2132398264 @default.
- W3100578076 cites W2132767279 @default.
- W3100578076 cites W2133307345 @default.
- W3100578076 cites W2135759551 @default.
- W3100578076 cites W2140042319 @default.
- W3100578076 cites W2144228067 @default.
- W3100578076 cites W2147099205 @default.
- W3100578076 cites W2151346868 @default.
- W3100578076 cites W2155091141 @default.
- W3100578076 cites W2155258622 @default.
- W3100578076 cites W2158921004 @default.
- W3100578076 cites W2161444621 @default.
- W3100578076 cites W2165131685 @default.
- W3100578076 cites W2169139342 @default.
- W3100578076 cites W2233241049 @default.
- W3100578076 cites W2252429173 @default.
- W3100578076 cites W2316061717 @default.
- W3100578076 cites W2399171942 @default.
- W3100578076 cites W2409587967 @default.
- W3100578076 cites W2534536090 @default.
- W3100578076 cites W2613165917 @default.
- W3100578076 cites W2741921612 @default.
- W3100578076 cites W2748077235 @default.