FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W3100597898> ?p ?o ?g. }

• W3100597898 startingPage "18" @default.
• W3100597898 abstract "Background: Human herpesvirus type 6 (HHV-6) is associated with roseola infantum during childhood followed by life-long latency that periodically reactivated in immunocompromised individuals . In spite of several studies to establish the pathogenic role of HHV-6 in lymphoid malignancies, the issue is still controversial. Objectives: This study was arranged to explore the association of HHV-6 infection in lymphoid malignancies using different serological and molecular techniques and to quantify the plasma viral load. Patients and methods: This cross-sectional case control study was conducted in National Center for Hematological Diseases (NCHD) at Al-Mustansiriyah University and Baghdad Teaching Hospital (BTH) in Baghdad-Iraq from September 2013 till April 2015. The patient group consists of 11 patients with Hodgkin lymphoma and 39 Non-Hodgkin's lymphoma of both sexes. The age range was between 15-80 years. The diagnosis of lymphomas was based on hematological and histopathological criteria. 59 apparently healthy individuals were enrolled as control group. They were chosen from unpaid blood donors. The age range was between 18-59 years. Human privacy was respected by taken participant's oral consensus. The seropositivity rate of anti-HHV-6 IgG and IgM antibodies were detected by enzyme linked immunosorbent assay (ELISA) and indirect immunofluorescent test (IFAT). The molecular detection and determination of plasma viral DNA load was achieved by quantitative polymerase chain reaction (qPCR). All data were statistically analyzed, and P values < 0.05 were considered significant. Results: The anti-HHV-6 IgG positivity rate by IFAT was insignificantly higher in HL (81.8% vs 61.0% p=0.186) and NHL (64.1% vs 61.0%, p =0.758) compared to control group. The anti-HHV-6 IgG positivity rate by ELISA was 81.8% in HL, 84.6% in NHL versus 72.9 % in controls which were insignificant in both groups (p=0.534 and p=0.173) respectively. The anti-HHV-6 IgM positivity rate by ELISA technique among patients with HL was significantly higher compared to controls (27.2% vs 6.8%, p= 0.038), but not significant in NHL (17.9% vs 6.8%, p= 0.086). HHV-6 DNA was detected in (27.3%) patients with HL by PCR technique, but none of the controls or NHL patients was positive. The plasma viral DNA load of the patient with HL was1.4± 0.3 x105 copies/milliliter. Conclusion: Although a higher anti-HHV-6 antibodies positivity rate among patients with HL and NHL, the pathogenic role of the virus in the development of these malignancies was difficult to be ascertain." @default.
• W3100597898 created "2020-11-23" @default.
• W3100597898 creator A5024289040 @default.
• W3100597898 creator A5065230791 @default.
• W3100597898 creator A5082171258 @default.
• W3100597898 date "2015-07-01" @default.
• W3100597898 modified "2023-09-23" @default.
• W3100597898 title "Association of human herpesvirus 6 with lymphoid malignancies in Iraqi patients" @default.
• W3100597898 hasPublicationYear "2015" @default.
• W3100597898 type Work @default.
• W3100597898 sameAs 3100597898 @default.
• W3100597898 citedByCount "0" @default.
• W3100597898 crossrefType "journal-article" @default.
• W3100597898 hasAuthorship W3100597898A5024289040 @default.
• W3100597898 hasAuthorship W3100597898A5065230791 @default.
• W3100597898 hasAuthorship W3100597898A5082171258 @default.
• W3100597898 hasConcept C126322002 @default.
• W3100597898 hasConcept C142462285 @default.
• W3100597898 hasConcept C159654299 @default.
• W3100597898 hasConcept C203014093 @default.
• W3100597898 hasConcept C2522874641 @default.
• W3100597898 hasConcept C2779338263 @default.
• W3100597898 hasConcept C45189115 @default.
• W3100597898 hasConcept C71924100 @default.
• W3100597898 hasConcept C90924648 @default.
• W3100597898 hasConceptScore W3100597898C126322002 @default.
• W3100597898 hasConceptScore W3100597898C142462285 @default.
• W3100597898 hasConceptScore W3100597898C159654299 @default.
• W3100597898 hasConceptScore W3100597898C203014093 @default.
• W3100597898 hasConceptScore W3100597898C2522874641 @default.
• W3100597898 hasConceptScore W3100597898C2779338263 @default.
• W3100597898 hasConceptScore W3100597898C45189115 @default.
• W3100597898 hasConceptScore W3100597898C71924100 @default.
• W3100597898 hasConceptScore W3100597898C90924648 @default.
• W3100597898 hasIssue "2" @default.
• W3100597898 hasLocation W31005978981 @default.
• W3100597898 hasOpenAccess W3100597898 @default.
• W3100597898 hasPrimaryLocation W31005978981 @default.
• W3100597898 hasRelatedWork W1964402693 @default.
• W3100597898 hasRelatedWork W1968347107 @default.
• W3100597898 hasRelatedWork W2000603287 @default.
• W3100597898 hasRelatedWork W2033619155 @default.
• W3100597898 hasRelatedWork W2116721927 @default.
• W3100597898 hasRelatedWork W2351011263 @default.
• W3100597898 hasRelatedWork W2370003717 @default.
• W3100597898 hasRelatedWork W2374824452 @default.
• W3100597898 hasRelatedWork W2399078699 @default.
• W3100597898 hasRelatedWork W2409613890 @default.
• W3100597898 hasRelatedWork W2413037496 @default.
• W3100597898 hasRelatedWork W2418999119 @default.
• W3100597898 hasRelatedWork W2471124506 @default.
• W3100597898 hasRelatedWork W2473545612 @default.
• W3100597898 hasRelatedWork W2558994266 @default.
• W3100597898 hasRelatedWork W2913469425 @default.
• W3100597898 hasRelatedWork W3011341313 @default.
• W3100597898 hasRelatedWork W3032337706 @default.
• W3100597898 hasRelatedWork W3048519987 @default.
• W3100597898 hasRelatedWork W3143014523 @default.
• W3100597898 hasVolume "4" @default.
• W3100597898 isParatext "false" @default.
• W3100597898 isRetracted "false" @default.
• W3100597898 magId "3100597898" @default.
• W3100597898 workType "article" @default.