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• W3100680672 abstract "The contractile ring, which plays critical roles in cytokinesis in fungal and animal cells, has fascinated biologists for decades. However, the basic question of how the non-muscle myosin-II and actin filaments are assembled into a ring structure to drive cytokinesis remains poorly understood. It is even more mysterious why and how the budding yeast Saccharomyces cerevisiae, the fission yeast Schizosaccharomyces pombe, and humans construct the ring structure with one, two, and three myosin-II isoforms, respectively. Here, we provide a comparative analysis of the roles of the non-muscle myosin-IIs in cytokinesis in these three model systems, with the goal of defining the common and unique features and highlighting the major questions regarding this family of proteins." @default.
• W3100680672 created "2020-11-23" @default.
• W3100680672 creator A5013707634 @default.
• W3100680672 creator A5017840192 @default.
• W3100680672 creator A5085625110 @default.
• W3100680672 date "2020-11-19" @default.
• W3100680672 modified "2023-10-02" @default.
• W3100680672 title "Comparative Analysis of the Roles of Non-muscle Myosin-IIs in Cytokinesis in Budding Yeast, Fission Yeast, and Mammalian Cells" @default.
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