Matches in SemOpenAlex for { <https://semopenalex.org/work/W3100681619> ?p ?o ?g. }
- W3100681619 endingPage "105755" @default.
- W3100681619 startingPage "105755" @default.
- W3100681619 abstract "The aim of this study is to determine the prevalence of intestinal helminths and protozoa in patients with ulcerative colitis (UC) and to estimate the influence of the anti-parasitic therapy on the course of the disease. The study was conducted at the Research Institute of Epidemiology, Microbiology and Infectious Diseases and Coloproctology Department of the Republic Clinical Hospital №1 of the Ministry of Health of the Republic of Uzbekistan. One hundred UC patients and 200 healthy individuals were examined by triple coproscopy. Additionally, 20, 25 and 22 UC patients with Blastocystis infection were treated with nitazoxanide (1.0 g/day), mesalazine (1.5-2 g/day) or a combination of nitazoxanide (1.0 g/day) and mesalazine (≥1.5-2 g/day) for 14 consecutive days, respectively. Parasitological, clinical and endoscopic examinations were conducted before therapy, immediately after and 6 and 12 weeks after therapy completion. The overall prevalence of helminths in UC patients and control individuals was not significantly different: 14±3.4% and 8.5±1.9%, respectively (OR: 1.7524; 95% CI: 0.8258 to 3.7186; P=0.1). Giardia lamblia was the most prevalent parasite in both groups, but the difference compared to the control was insignificant (OR: 0.4565; 95% CI: 0.2020 to 1.0318; P=0.05). A significantly higher prevalence of Blastocystis sp., Chilomastix mesnili and Iodamoeba butschlii in UC patients compared to control individuals was found (P<0.0005): 65.0%, 14.0% and 22.0%, respectively. During all follow-up periods, the clinical response and clinical remission were not statistically different between the groups (P>0.05). Mucosal healing immediately and 6 weeks after therapy with a combination of nitazoxanide with mesalazine was significantly better than with a monotherapy of nitazoxanide, respectively (P<0.05). UC patients treated with a combination of nitazoxanide with mesalazine showed better mucosal healing than in patients treated with a monotherapy of mesalazine (P>0.05). Diagnosis of Blastocystis sp. should be introduced in the complex examination of UC patients. Further clinical studies are necessary for assessment of the efficiency of anti-Blastocystis therapy in UC patients." @default.
- W3100681619 created "2020-11-23" @default.
- W3100681619 creator A5010401159 @default.
- W3100681619 creator A5024308729 @default.
- W3100681619 creator A5042191034 @default.
- W3100681619 creator A5065327772 @default.
- W3100681619 creator A5068433006 @default.
- W3100681619 creator A5087888448 @default.
- W3100681619 date "2021-01-01" @default.
- W3100681619 modified "2023-09-30" @default.
- W3100681619 title "Intestinal protozoa and helminths in ulcerative colitis and the influence of anti-parasitic therapy on the course of the disease" @default.
- W3100681619 cites W152975134 @default.
- W3100681619 cites W1656494246 @default.
- W3100681619 cites W1804680700 @default.
- W3100681619 cites W1857457305 @default.
- W3100681619 cites W1869565422 @default.
- W3100681619 cites W1964223647 @default.
- W3100681619 cites W1970196066 @default.
- W3100681619 cites W1973566986 @default.
- W3100681619 cites W1975136503 @default.
- W3100681619 cites W1977132715 @default.
- W3100681619 cites W1981017422 @default.
- W3100681619 cites W1982367660 @default.
- W3100681619 cites W1991522326 @default.
- W3100681619 cites W1992248467 @default.
- W3100681619 cites W1994882377 @default.
- W3100681619 cites W2005772242 @default.
- W3100681619 cites W2012285185 @default.
- W3100681619 cites W2017223808 @default.
- W3100681619 cites W2035831689 @default.
- W3100681619 cites W2056629400 @default.
- W3100681619 cites W2056650427 @default.
- W3100681619 cites W2062558013 @default.
- W3100681619 cites W2072157304 @default.
- W3100681619 cites W2075180225 @default.
- W3100681619 cites W2078557216 @default.
- W3100681619 cites W2083594724 @default.
- W3100681619 cites W2087210088 @default.
- W3100681619 cites W2097875133 @default.
- W3100681619 cites W2101895446 @default.
- W3100681619 cites W2115524426 @default.
- W3100681619 cites W2120615647 @default.
- W3100681619 cites W2134568639 @default.
- W3100681619 cites W2149892566 @default.
- W3100681619 cites W2152812038 @default.
- W3100681619 cites W2158820172 @default.
- W3100681619 cites W2188248802 @default.
- W3100681619 cites W2215723365 @default.
- W3100681619 cites W2303817400 @default.
- W3100681619 cites W2345609078 @default.
- W3100681619 cites W2345848718 @default.
- W3100681619 cites W2356183854 @default.
- W3100681619 cites W2417953544 @default.
- W3100681619 cites W2425423977 @default.
- W3100681619 cites W2489652560 @default.
- W3100681619 cites W2491042073 @default.
- W3100681619 cites W2515182048 @default.
- W3100681619 cites W2519968006 @default.
- W3100681619 cites W2563484386 @default.
- W3100681619 cites W2588997555 @default.
- W3100681619 cites W2595836467 @default.
- W3100681619 cites W2737558965 @default.
- W3100681619 cites W2747743284 @default.
- W3100681619 cites W2778416039 @default.
- W3100681619 cites W2886305760 @default.
- W3100681619 cites W2888565392 @default.
- W3100681619 cites W2898968168 @default.
- W3100681619 cites W2911082921 @default.
- W3100681619 cites W2916962020 @default.
- W3100681619 cites W4290198580 @default.
- W3100681619 cites W63490377 @default.
- W3100681619 doi "https://doi.org/10.1016/j.actatropica.2020.105755" @default.
- W3100681619 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/33188747" @default.
- W3100681619 hasPublicationYear "2021" @default.
- W3100681619 type Work @default.
- W3100681619 sameAs 3100681619 @default.
- W3100681619 citedByCount "3" @default.
- W3100681619 countsByYear W31006816192021 @default.
- W3100681619 countsByYear W31006816192023 @default.
- W3100681619 crossrefType "journal-article" @default.
- W3100681619 hasAuthorship W3100681619A5010401159 @default.
- W3100681619 hasAuthorship W3100681619A5024308729 @default.
- W3100681619 hasAuthorship W3100681619A5042191034 @default.
- W3100681619 hasAuthorship W3100681619A5065327772 @default.
- W3100681619 hasAuthorship W3100681619A5068433006 @default.
- W3100681619 hasAuthorship W3100681619A5087888448 @default.
- W3100681619 hasConcept C126322002 @default.
- W3100681619 hasConcept C142724271 @default.
- W3100681619 hasConcept C165901193 @default.
- W3100681619 hasConcept C203014093 @default.
- W3100681619 hasConcept C2777276848 @default.
- W3100681619 hasConcept C2778092740 @default.
- W3100681619 hasConcept C2779134260 @default.
- W3100681619 hasConcept C2779174533 @default.
- W3100681619 hasConcept C2780479503 @default.
- W3100681619 hasConcept C2780626423 @default.
- W3100681619 hasConcept C61716771 @default.
- W3100681619 hasConcept C71924100 @default.