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• W3100744384 abstract "We consider a population dynamics model coupling cell growth to a diffusion in the space of metabolic phenotypes as it can be obtained from realistic constraints-based modelling. In the asymptotic regime of slow diffusion, that coincides with the relevant experimental range, the resulting non-linear Fokker-Planck equation is solved for the steady state in the WKB approximation that maps it into the ground state of a quantum particle in an Airy potential plus a centrifugal term. We retrieve scaling laws for growth rate fluctuations and time response with respect to the distance from the maximum growth rate suggesting that suboptimal populations can have a faster response to perturbations." @default.
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• W3100744384 date "2016-12-30" @default.
• W3100744384 modified "2023-10-16" @default.
• W3100744384 title "Asymptotic analysis of noisy fitness maximization, applied to metabolism & growth" @default.
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• W3100744384 doi "https://doi.org/10.1088/1742-5468/aa4e8f" @default.
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