FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W3100816922> ?p ?o ?g. }

• W3100816922 abstract "Terahertz radiation (THZ or Terahertz) is that part of the electromagnetic spectrum lying between the electricaldomain of microwaves and the optical domain of infrared radiation (0.1 THz to 10 THz), which is now bloomingwith a myriad of new applications after decades where it was only considered as some sort of technological ‘gap’,mainly because of a lack of standardized generation and detection systems.The most common applications of THZ are in the industrial domain as a non-contact means to performmaterial identification, measure thickness of plastic objects and coatings, as well as carry out spectroscopicanalysis of packaged substances. It is also used for cultural heritage diagnostics, security inspections (body scan)and many other uses.The intrinsic safety of THZ, due to its characteristic low photon energy that cannot cause ionization, makes itsuitable for probing living tissues, and a highly attractive candidate for sensing and monitoring systems in thebiological and biomedical fields. We are particularly interested in the use of THZ as a complementary instrumentin the therapy of skin cancer, which is becoming an increasingly common occurrence in developed countries andimposes a significant burden on society.After being reflected by the skin, THZ carries information about the refractive index of the water contained inepidermal tissue that can be used to infer the temperature and hydration of the skin. This could prove to be invaluableas a monitoring tool during sessions of Photothermal Therapy (PTT) and enable us to assess its outcome afterwards.This thesis is part of a larger research project that aims first to demonstrate the feasibility and utility of aTHZ-based monitoring system for PTT and then to refine the analysis algorithms and measurement proceduresto allow this idea to exit the physics research laboratory and become a tool commonly used in the healthcaresystem. This work focuses on the development of a fast and reliable data acquisition system that will constitutethe basis of the project. The setup will have to be powerful and flexible enough to accommodate the necessitiesof a research environment, but present an interface that is simple to use and understand for operators that have nospecific training in spectroscopy and nonlinear optics.The first chapter briefly reviews the medical and social issues that physics is called upon to address and summarizeswhy this new approach to thermal monitoring is an interesting alternative to other well-established techniques. The second chapter illustrates the state of the art in the field of THZ generation and detection, in order to allow usto i) evaluate the viability of the various options for use in a clinical context and ii) choose the most appropriate ones.The third chapter describes in detail the setup itself, from the point of view of both the hardware componentsand the software used to drive them, thereby providing adequate justification for the choice of components andsoftware architecture. This chapter also contains the description of the measurement procedures employed foreach operating mode of the setup.The fourth chapter describes a set of measurements performed with the aim i) of characterizing the instrumentused, ii) determining how its operating mode affects the collected data and iii) establishing the limits within whichthe settings of the various sub-systems should lie to ensure optimal performance. One of the tests involves thesimulation of a PTT session on a porcine skin model to show that the setup is actually capable of performing itsfunction, in conditions as close as possible to its intended use.The fifth chapter contains the conclusion and several suggestions for future development of the system." @default.
• W3100816922 created "2020-11-23" @default.
• W3100816922 creator A5035399617 @default.
• W3100816922 date "2020-01-01" @default.
• W3100816922 modified "2023-09-27" @default.
• W3100816922 title "Development of a prototype Time Domain Spectroscopysystem for in vivo terahertz thermal imaging." @default.
• W3100816922 hasPublicationYear "2020" @default.
• W3100816922 type Work @default.
• W3100816922 sameAs 3100816922 @default.
• W3100816922 citedByCount "0" @default.
• W3100816922 crossrefType "journal-article" @default.
• W3100816922 hasAuthorship W3100816922A5035399617 @default.
• W3100816922 hasConcept C107816215 @default.
• W3100816922 hasConcept C112184408 @default.
• W3100816922 hasConcept C120665830 @default.
• W3100816922 hasConcept C121332964 @default.
• W3100816922 hasConcept C133033976 @default.
• W3100816922 hasConcept C155761240 @default.
• W3100816922 hasConcept C170563983 @default.
• W3100816922 hasConcept C192562407 @default.
• W3100816922 hasConcept C19527891 @default.
• W3100816922 hasConcept C41008148 @default.
• W3100816922 hasConcept C44838205 @default.
• W3100816922 hasConcept C49040817 @default.
• W3100816922 hasConcept C520434653 @default.
• W3100816922 hasConcept C76155785 @default.
• W3100816922 hasConceptScore W3100816922C107816215 @default.
• W3100816922 hasConceptScore W3100816922C112184408 @default.
• W3100816922 hasConceptScore W3100816922C120665830 @default.
• W3100816922 hasConceptScore W3100816922C121332964 @default.
• W3100816922 hasConceptScore W3100816922C133033976 @default.
• W3100816922 hasConceptScore W3100816922C155761240 @default.
• W3100816922 hasConceptScore W3100816922C170563983 @default.
• W3100816922 hasConceptScore W3100816922C192562407 @default.
• W3100816922 hasConceptScore W3100816922C19527891 @default.
• W3100816922 hasConceptScore W3100816922C41008148 @default.
• W3100816922 hasConceptScore W3100816922C44838205 @default.
• W3100816922 hasConceptScore W3100816922C49040817 @default.
• W3100816922 hasConceptScore W3100816922C520434653 @default.
• W3100816922 hasConceptScore W3100816922C76155785 @default.
• W3100816922 hasLocation W31008169221 @default.
• W3100816922 hasOpenAccess W3100816922 @default.
• W3100816922 hasPrimaryLocation W31008169221 @default.
• W3100816922 hasRelatedWork W1025721084 @default.
• W3100816922 hasRelatedWork W113707693 @default.
• W3100816922 hasRelatedWork W135112185 @default.
• W3100816922 hasRelatedWork W1560992670 @default.
• W3100816922 hasRelatedWork W185986571 @default.
• W3100816922 hasRelatedWork W2024294058 @default.
• W3100816922 hasRelatedWork W2030179383 @default.
• W3100816922 hasRelatedWork W2076114916 @default.
• W3100816922 hasRelatedWork W2284459219 @default.
• W3100816922 hasRelatedWork W2287440322 @default.
• W3100816922 hasRelatedWork W230875712 @default.
• W3100816922 hasRelatedWork W2583607138 @default.
• W3100816922 hasRelatedWork W2780156615 @default.
• W3100816922 hasRelatedWork W2891636022 @default.
• W3100816922 hasRelatedWork W3037299001 @default.
• W3100816922 hasRelatedWork W3136741547 @default.
• W3100816922 hasRelatedWork W3182644980 @default.
• W3100816922 hasRelatedWork W3196296175 @default.
• W3100816922 hasRelatedWork W81889601 @default.
• W3100816922 hasRelatedWork W2945096372 @default.
• W3100816922 isParatext "false" @default.
• W3100816922 isRetracted "false" @default.
• W3100816922 magId "3100816922" @default.
• W3100816922 workType "article" @default.