Matches in SemOpenAlex for { <https://semopenalex.org/work/W3100968774> ?p ?o ?g. }
- W3100968774 endingPage "117223" @default.
- W3100968774 startingPage "117223" @default.
- W3100968774 abstract "Toxoplasmosis is an opportunistic infection caused by Toxoplasma gondii (TG), which affects one third of the global human population and commonly involves the central nervous system (CNS)/brain despite the so-called CNS immune privilege. Symptomatic clinical disease of TG infection is much more commonly associated with immunodeficiency; clinicopathological manifestations of CNS toxoplasmosis are linked to individual immune responses including the CNS infiltration of T-cells that are thought to prevent the disease. In patients with autoimmune diseases, immune status is complicated mainly byimmunosuppressant and/or immunomodulatory treatment but typically accompanied by infiltration of T-cells that supposedly fight against toxoplasmosis. In this article, we review characteristics of CNS toxoplasmosis comparatively in immunocompromised patients, immunocompetent patients, and patients with coexisting autoimmune diseases, as well as CNS immune responses to toxoplasmosis with a representative case to demonstrate brain lesions at different stages. In addition to general understanding of CNS toxoplasmosis, our review reveals that clinical manifestations of CNS toxoplasmosis are commonly nonspecific, and incidental pathological findings of TG infection are relatively common in immunocompetent patients and patients with autoimmune diseases (compared to immunocompromised patients); CNS immune responses such as T-cell infiltrates vary in acute and chronic lesions of brain toxoplasmosis." @default.
- W3100968774 created "2020-11-23" @default.
- W3100968774 creator A5013473072 @default.
- W3100968774 creator A5032304307 @default.
- W3100968774 creator A5057505304 @default.
- W3100968774 creator A5076412818 @default.
- W3100968774 date "2021-01-01" @default.
- W3100968774 modified "2023-10-18" @default.
- W3100968774 title "Toxoplasmosis of the central nervous system: Manifestations vary with immune responses" @default.
- W3100968774 cites W1531644117 @default.
- W3100968774 cites W1553735692 @default.
- W3100968774 cites W1600893464 @default.
- W3100968774 cites W1811112134 @default.
- W3100968774 cites W1888830013 @default.
- W3100968774 cites W1972819314 @default.
- W3100968774 cites W1974282283 @default.
- W3100968774 cites W1975110303 @default.
- W3100968774 cites W1977401509 @default.
- W3100968774 cites W1983128219 @default.
- W3100968774 cites W1990178079 @default.
- W3100968774 cites W1997190821 @default.
- W3100968774 cites W1998047654 @default.
- W3100968774 cites W1998051465 @default.
- W3100968774 cites W1999105483 @default.
- W3100968774 cites W2002764344 @default.
- W3100968774 cites W2004234339 @default.
- W3100968774 cites W2012364722 @default.
- W3100968774 cites W2015710784 @default.
- W3100968774 cites W2026692883 @default.
- W3100968774 cites W2030470434 @default.
- W3100968774 cites W2032432537 @default.
- W3100968774 cites W2037083934 @default.
- W3100968774 cites W2037655228 @default.
- W3100968774 cites W2044400894 @default.
- W3100968774 cites W2046105178 @default.
- W3100968774 cites W2056486414 @default.
- W3100968774 cites W2060379424 @default.
- W3100968774 cites W2063921781 @default.
- W3100968774 cites W2066428609 @default.
- W3100968774 cites W2068016284 @default.
- W3100968774 cites W2069879214 @default.
- W3100968774 cites W2072850913 @default.
- W3100968774 cites W2073454575 @default.
- W3100968774 cites W2076396080 @default.
- W3100968774 cites W2077783001 @default.
- W3100968774 cites W2089356141 @default.
- W3100968774 cites W2103644250 @default.
- W3100968774 cites W2105253760 @default.
- W3100968774 cites W2106321977 @default.
- W3100968774 cites W2108197744 @default.
- W3100968774 cites W2109954197 @default.
- W3100968774 cites W2118208608 @default.
- W3100968774 cites W2125722420 @default.
- W3100968774 cites W2130716686 @default.
- W3100968774 cites W2138586761 @default.
- W3100968774 cites W2142713800 @default.
- W3100968774 cites W2152374584 @default.
- W3100968774 cites W2153027132 @default.
- W3100968774 cites W2156154614 @default.
- W3100968774 cites W2172275045 @default.
- W3100968774 cites W2227808742 @default.
- W3100968774 cites W2282930798 @default.
- W3100968774 cites W2312393177 @default.
- W3100968774 cites W2314879238 @default.
- W3100968774 cites W2337467635 @default.
- W3100968774 cites W2427683573 @default.
- W3100968774 cites W2612857360 @default.
- W3100968774 cites W2774292470 @default.
- W3100968774 cites W2791984538 @default.
- W3100968774 cites W2794223083 @default.
- W3100968774 cites W2801079732 @default.
- W3100968774 cites W2807455706 @default.
- W3100968774 cites W2884506095 @default.
- W3100968774 cites W2903094584 @default.
- W3100968774 cites W2913477873 @default.
- W3100968774 cites W2926432634 @default.
- W3100968774 cites W2949243209 @default.
- W3100968774 cites W2968919017 @default.
- W3100968774 cites W2971800568 @default.
- W3100968774 cites W2995402753 @default.
- W3100968774 cites W3000111275 @default.
- W3100968774 cites W3002010299 @default.
- W3100968774 cites W3012547940 @default.
- W3100968774 cites W4211140781 @default.
- W3100968774 doi "https://doi.org/10.1016/j.jns.2020.117223" @default.
- W3100968774 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/33213861" @default.
- W3100968774 hasPublicationYear "2021" @default.
- W3100968774 type Work @default.
- W3100968774 sameAs 3100968774 @default.
- W3100968774 citedByCount "11" @default.
- W3100968774 countsByYear W31009687742021 @default.
- W3100968774 countsByYear W31009687742022 @default.
- W3100968774 countsByYear W31009687742023 @default.
- W3100968774 crossrefType "journal-article" @default.
- W3100968774 hasAuthorship W3100968774A5013473072 @default.
- W3100968774 hasAuthorship W3100968774A5032304307 @default.
- W3100968774 hasAuthorship W3100968774A5057505304 @default.
- W3100968774 hasAuthorship W3100968774A5076412818 @default.