Matches in SemOpenAlex for { <https://semopenalex.org/work/W3100974713> ?p ?o ?g. }
Showing items 1 to 62 of
62
with 100 items per page.
- W3100974713 abstract "Background Neonatal seizures are a relatively common occurrence associated with an adverse outcome. Their recognition is difficult. The clinical signs are often subtle and a substantial proportion are non-clinical. The introduction of cerebral function monitoring (CFM) has led to an increased recognition of seizures. Creating a guideline is difficult due to lack of evidence for the drugs used and lack of international consensus. Aim To benchmark the management of neonatal seizures. Method 50 neonatal intensive care units within the UK (more than four intensive treatment unit cots) were contacted by telephone and completed a structured questionnaire. Results 20% of units did not have a guideline. Seizure recognition: CFM was used in 36 (72%) units, EEG in 22 (44%) and video-EEG in one. Treatment: 1st line: phenobarbitone was used by all, although with variations in dosage and interval. 2nd line: 29 (73%) used phenytoin; others included midazolam, clonazepam, lignocaine. 3rd line: 14 (35%) used clonazepam; others included paraldehyde, midazolam, lignocaine, lorazepam, diazepam and sodium valproate. 4th line: 25% used paraldehyde; others included thiopentone and heminevrine. Pyridoxine: 68% of units incorporated this into their guideline. Non-clinical seizures: three units had a guideline. Only a third of units considered treating them. Imaging: 94% performed a cranial ultrasound scan. 58% considered computed tomography scan. Only 10% obtained a magnetic resonance imaging scan in every baby. Conclusions This study confirms there is marked variation in the management of newborn seizures. National guidance would be welcome. Despite increased recognition of CFM, only 6% of units have guidance on the treatment of non-clinical seizures and we believe there is evidence supporting their treatment." @default.
- W3100974713 created "2020-11-23" @default.
- W3100974713 creator A5034980645 @default.
- W3100974713 creator A5070115014 @default.
- W3100974713 date "2008-11-01" @default.
- W3100974713 modified "2023-09-23" @default.
- W3100974713 title "MANAGING SEIZURES IN THE NEONATAL PERIOD: IS THERE A UK CONCENSUS?" @default.
- W3100974713 hasPublicationYear "2008" @default.
- W3100974713 type Work @default.
- W3100974713 sameAs 3100974713 @default.
- W3100974713 citedByCount "0" @default.
- W3100974713 crossrefType "journal-article" @default.
- W3100974713 hasAuthorship W3100974713A5034980645 @default.
- W3100974713 hasAuthorship W3100974713A5070115014 @default.
- W3100974713 hasConcept C142724271 @default.
- W3100974713 hasConcept C187212893 @default.
- W3100974713 hasConcept C2776814716 @default.
- W3100974713 hasConcept C2777091541 @default.
- W3100974713 hasConcept C2778000748 @default.
- W3100974713 hasConcept C2779426884 @default.
- W3100974713 hasConcept C2779706987 @default.
- W3100974713 hasConcept C2780182762 @default.
- W3100974713 hasConcept C42219234 @default.
- W3100974713 hasConcept C71924100 @default.
- W3100974713 hasConceptScore W3100974713C142724271 @default.
- W3100974713 hasConceptScore W3100974713C187212893 @default.
- W3100974713 hasConceptScore W3100974713C2776814716 @default.
- W3100974713 hasConceptScore W3100974713C2777091541 @default.
- W3100974713 hasConceptScore W3100974713C2778000748 @default.
- W3100974713 hasConceptScore W3100974713C2779426884 @default.
- W3100974713 hasConceptScore W3100974713C2779706987 @default.
- W3100974713 hasConceptScore W3100974713C2780182762 @default.
- W3100974713 hasConceptScore W3100974713C42219234 @default.
- W3100974713 hasConceptScore W3100974713C71924100 @default.
- W3100974713 hasLocation W31009747131 @default.
- W3100974713 hasOpenAccess W3100974713 @default.
- W3100974713 hasPrimaryLocation W31009747131 @default.
- W3100974713 hasRelatedWork W1974968449 @default.
- W3100974713 hasRelatedWork W2034709361 @default.
- W3100974713 hasRelatedWork W2058643562 @default.
- W3100974713 hasRelatedWork W2135114611 @default.
- W3100974713 hasRelatedWork W2143435007 @default.
- W3100974713 hasRelatedWork W2146717275 @default.
- W3100974713 hasRelatedWork W2162284004 @default.
- W3100974713 hasRelatedWork W2167309854 @default.
- W3100974713 hasRelatedWork W2283470097 @default.
- W3100974713 hasRelatedWork W2325601556 @default.
- W3100974713 hasRelatedWork W2412284874 @default.
- W3100974713 hasRelatedWork W267714201 @default.
- W3100974713 hasRelatedWork W2742843792 @default.
- W3100974713 hasRelatedWork W2927565180 @default.
- W3100974713 hasRelatedWork W2980893532 @default.
- W3100974713 hasRelatedWork W3071688102 @default.
- W3100974713 hasRelatedWork W3092465340 @default.
- W3100974713 hasRelatedWork W3186631665 @default.
- W3100974713 hasRelatedWork W3205543424 @default.
- W3100974713 hasRelatedWork W349810933 @default.
- W3100974713 hasVolume "93" @default.
- W3100974713 isParatext "false" @default.
- W3100974713 isRetracted "false" @default.
- W3100974713 magId "3100974713" @default.
- W3100974713 workType "article" @default.