FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W3101618110> ?p ?o ?g. }

• W3101618110 endingPage "105" @default.
• W3101618110 startingPage "95" @default.
• W3101618110 abstract "This study examined the association between statin usage (discontinued, reduced or continued) and two-year death following a 21% increase in the Pharmaceutical Benefits Scheme (PBS) consumer co-payment in Western Australia.A retrospective observational study in Western Australia using linked administrative Commonwealth PBS data and State hospital inpatient and death data (n = 207,066) was undertaken. We explored the two-year all-cause and ischemic heart disease(IHD)/stroke-specific-death in individuals who discontinued, reduced or continued statin medication following the January 2005 PBS co-payment increase, overall, by beneficiary status (general population vs. social security recipients) and by a history of admission for ischemic heart disease or stroke. Non-cardiovascular (CVD)-related death was also considered.In the first six months of 2005, 3.3% discontinued, 12.5% reduced and 84.2% continued statin therapy. We found those who discontinued statins were also likely to discontinue at least two other medicines compared to those who continued therapy. There were 4,607 all-cause deaths. For IHD/stroke-specific death, there were 1,317. For all non-CVD-related death, there were 2,808 deaths during the 2-year follow-up period. Cox regression models, adjusted for demographic and clinical characteristics, showed a 39%-61% increase in the risk of all-cause death for individuals who reduced or discontinued statin medication compared to those who continued their statin medication (Discontinued: Adj HR = 1.61, 95% CI 1.40-1.85; Reduced: Adj HR = 1.39, 95% CI 1.28-1.51). For IHD/stroke-specific death, there was an increased risk of death by 28-76% (Discontinued: Adj sHR = 1.76, 95% CI 1.37-2.27; Reduced: Adj sHR = 1.28, 95% CI 1.10-1.49), and for non-CVD-related death, there was an increased risk of death by 44-57% (Discontinued: Adj sHR = 1.57, 95% CI 1.31-1.88; Reduced: Adj sHR = 1.44, 95% CI 1.30-1.60), for individuals who discontinued or reduced their statin medication compared to those who continued.Patients who discontinued their statin therapy had a significantly increased risk of IHD and stroke death. Health professionals should be aware that large co-payment changes may be associated with patients discontinuing or reducing medicines to their health detriment. Factors that lead to such changes in patient medication-taking behaviour need to be considered and addressed at the clinical and policy levels." @default.
• W3101618110 created "2020-11-23" @default.
• W3101618110 creator A5011559148 @default.
• W3101618110 creator A5016849312 @default.
• W3101618110 creator A5027557581 @default.
• W3101618110 creator A5030759827 @default.
• W3101618110 creator A5051519595 @default.
• W3101618110 creator A5063416292 @default.
• W3101618110 creator A5065005309 @default.
• W3101618110 creator A5070816464 @default.
• W3101618110 date "2020-11-08" @default.
• W3101618110 modified "2023-10-17" @default.
• W3101618110 title "Increased risk of 2-year death in patients who discontinued their use of statins" @default.
• W3101618110 cites W1543389126 @default.
• W3101618110 cites W1948458971 @default.
• W3101618110 cites W2000445173 @default.
• W3101618110 cites W2027670770 @default.
• W3101618110 cites W2031481357 @default.
• W3101618110 cites W2038981426 @default.
• W3101618110 cites W2049351899 @default.
• W3101618110 cites W2063844762 @default.
• W3101618110 cites W2109106415 @default.
• W3101618110 cites W2109398970 @default.
• W3101618110 cites W2115150707 @default.
• W3101618110 cites W2144129180 @default.
• W3101618110 cites W2157457667 @default.
• W3101618110 cites W2160544378 @default.
• W3101618110 cites W2218843182 @default.
• W3101618110 cites W2402599050 @default.
• W3101618110 cites W2802067770 @default.
• W3101618110 doi "https://doi.org/10.1177/1355819620965610" @default.
• W3101618110 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/33161778" @default.
• W3101618110 hasPublicationYear "2020" @default.
• W3101618110 type Work @default.
• W3101618110 sameAs 3101618110 @default.
• W3101618110 citedByCount "1" @default.
• W3101618110 countsByYear W31016181102023 @default.
• W3101618110 crossrefType "journal-article" @default.
• W3101618110 hasAuthorship W3101618110A5011559148 @default.
• W3101618110 hasAuthorship W3101618110A5016849312 @default.
• W3101618110 hasAuthorship W3101618110A5027557581 @default.
• W3101618110 hasAuthorship W3101618110A5030759827 @default.
• W3101618110 hasAuthorship W3101618110A5051519595 @default.
• W3101618110 hasAuthorship W3101618110A5063416292 @default.
• W3101618110 hasAuthorship W3101618110A5065005309 @default.
• W3101618110 hasAuthorship W3101618110A5070816464 @default.
• W3101618110 hasConcept C126322002 @default.
• W3101618110 hasConcept C127413603 @default.
• W3101618110 hasConcept C167135981 @default.
• W3101618110 hasConcept C194828623 @default.
• W3101618110 hasConcept C2776839432 @default.
• W3101618110 hasConcept C2779134260 @default.
• W3101618110 hasConcept C2780645631 @default.
• W3101618110 hasConcept C2908647359 @default.
• W3101618110 hasConcept C29374701 @default.
• W3101618110 hasConcept C50382708 @default.
• W3101618110 hasConcept C71924100 @default.
• W3101618110 hasConcept C78519656 @default.
• W3101618110 hasConcept C99454951 @default.
• W3101618110 hasConceptScore W3101618110C126322002 @default.
• W3101618110 hasConceptScore W3101618110C127413603 @default.
• W3101618110 hasConceptScore W3101618110C167135981 @default.
• W3101618110 hasConceptScore W3101618110C194828623 @default.
• W3101618110 hasConceptScore W3101618110C2776839432 @default.
• W3101618110 hasConceptScore W3101618110C2779134260 @default.
• W3101618110 hasConceptScore W3101618110C2780645631 @default.
• W3101618110 hasConceptScore W3101618110C2908647359 @default.
• W3101618110 hasConceptScore W3101618110C29374701 @default.
• W3101618110 hasConceptScore W3101618110C50382708 @default.
• W3101618110 hasConceptScore W3101618110C71924100 @default.
• W3101618110 hasConceptScore W3101618110C78519656 @default.
• W3101618110 hasConceptScore W3101618110C99454951 @default.
• W3101618110 hasFunder F4320334705 @default.
• W3101618110 hasIssue "2" @default.
• W3101618110 hasLocation W31016181101 @default.
• W3101618110 hasLocation W31016181102 @default.
• W3101618110 hasOpenAccess W3101618110 @default.
• W3101618110 hasPrimaryLocation W31016181101 @default.
• W3101618110 hasRelatedWork W1629355360 @default.
• W3101618110 hasRelatedWork W2014757808 @default.
• W3101618110 hasRelatedWork W2046141968 @default.
• W3101618110 hasRelatedWork W2168890575 @default.
• W3101618110 hasRelatedWork W2593300661 @default.
• W3101618110 hasRelatedWork W2765307087 @default.
• W3101618110 hasRelatedWork W3137020108 @default.
• W3101618110 hasRelatedWork W4213434767 @default.
• W3101618110 hasRelatedWork W4231538954 @default.
• W3101618110 hasRelatedWork W4236168938 @default.
• W3101618110 hasVolume "26" @default.
• W3101618110 isParatext "false" @default.
• W3101618110 isRetracted "false" @default.
• W3101618110 magId "3101618110" @default.
• W3101618110 workType "article" @default.