Matches in SemOpenAlex for { <https://semopenalex.org/work/W3101767498> ?p ?o ?g. }
- W3101767498 endingPage "1541" @default.
- W3101767498 startingPage "1541" @default.
- W3101767498 abstract "Direct interaction between intrinsically disordered proteins (IDPs) is often difficult to characterize hampering the elucidation of their binding mechanism. Particularly challenging is the study of fuzzy complexes, in which the intrinsically disordered proteins or regions retain conformational freedom within the assembly. To date, nuclear magnetic resonance spectroscopy has proven to be one of the most powerful techniques to characterize at the atomic level intrinsically disordered proteins and their interactions, including those cases where the formed complexes are highly dynamic. Here, we present the characterization of the interaction between a viral protein, the Early region 1A protein from Adenovirus (E1A), and a disordered region of the human CREB-binding protein, namely the fourth intrinsically disordered linker CBP-ID4. E1A was widely studied as a prototypical viral oncogene. Its interaction with two folded domains of CBP was mapped, providing hints for understanding some functional aspects of the interaction with this transcriptional coactivator. However, the role of the flexible linker connecting these two globular domains of CBP in this interaction was never explored before." @default.
- W3101767498 created "2020-11-23" @default.
- W3101767498 creator A5002721900 @default.
- W3101767498 creator A5033448495 @default.
- W3101767498 creator A5055129253 @default.
- W3101767498 date "2020-11-11" @default.
- W3101767498 modified "2023-09-27" @default.
- W3101767498 title "Adenoviral E1A Exploits Flexibility and Disorder to Target Cellular Proteins" @default.
- W3101767498 cites W1884928119 @default.
- W3101767498 cites W1966063731 @default.
- W3101767498 cites W1966823793 @default.
- W3101767498 cites W1971055167 @default.
- W3101767498 cites W1986322598 @default.
- W3101767498 cites W1989800988 @default.
- W3101767498 cites W1995685468 @default.
- W3101767498 cites W2004321165 @default.
- W3101767498 cites W2006192061 @default.
- W3101767498 cites W2008332643 @default.
- W3101767498 cites W2010605653 @default.
- W3101767498 cites W2020886479 @default.
- W3101767498 cites W2030071623 @default.
- W3101767498 cites W2034718152 @default.
- W3101767498 cites W2034766560 @default.
- W3101767498 cites W2038895598 @default.
- W3101767498 cites W2044157441 @default.
- W3101767498 cites W2052699134 @default.
- W3101767498 cites W2054191418 @default.
- W3101767498 cites W2078159738 @default.
- W3101767498 cites W2078480746 @default.
- W3101767498 cites W2079635715 @default.
- W3101767498 cites W2086862822 @default.
- W3101767498 cites W2090318167 @default.
- W3101767498 cites W2090332697 @default.
- W3101767498 cites W2092216600 @default.
- W3101767498 cites W2093362562 @default.
- W3101767498 cites W2095217266 @default.
- W3101767498 cites W2122536893 @default.
- W3101767498 cites W2127131519 @default.
- W3101767498 cites W2132180320 @default.
- W3101767498 cites W2132629607 @default.
- W3101767498 cites W2141776442 @default.
- W3101767498 cites W2147610376 @default.
- W3101767498 cites W2148349600 @default.
- W3101767498 cites W2153438491 @default.
- W3101767498 cites W2159313431 @default.
- W3101767498 cites W2172238536 @default.
- W3101767498 cites W2178504451 @default.
- W3101767498 cites W2285303417 @default.
- W3101767498 cites W2294967868 @default.
- W3101767498 cites W2322726167 @default.
- W3101767498 cites W2493341306 @default.
- W3101767498 cites W2528867623 @default.
- W3101767498 cites W2727686366 @default.
- W3101767498 cites W2788194767 @default.
- W3101767498 cites W2791248032 @default.
- W3101767498 cites W2802273862 @default.
- W3101767498 cites W2804980767 @default.
- W3101767498 cites W2810226957 @default.
- W3101767498 cites W2894115584 @default.
- W3101767498 cites W2912126500 @default.
- W3101767498 cites W2982303737 @default.
- W3101767498 cites W2989715752 @default.
- W3101767498 cites W3007953280 @default.
- W3101767498 cites W3014505574 @default.
- W3101767498 cites W3031661900 @default.
- W3101767498 cites W865467657 @default.
- W3101767498 doi "https://doi.org/10.3390/biom10111541" @default.
- W3101767498 hasPubMedCentralId "https://www.ncbi.nlm.nih.gov/pmc/articles/7698142" @default.
- W3101767498 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/33187345" @default.
- W3101767498 hasPublicationYear "2020" @default.
- W3101767498 type Work @default.
- W3101767498 sameAs 3101767498 @default.
- W3101767498 citedByCount "10" @default.
- W3101767498 countsByYear W31017674982021 @default.
- W3101767498 countsByYear W31017674982022 @default.
- W3101767498 countsByYear W31017674982023 @default.
- W3101767498 crossrefType "journal-article" @default.
- W3101767498 hasAuthorship W3101767498A5002721900 @default.
- W3101767498 hasAuthorship W3101767498A5033448495 @default.
- W3101767498 hasAuthorship W3101767498A5055129253 @default.
- W3101767498 hasBestOaLocation W31017674981 @default.
- W3101767498 hasConcept C111919701 @default.
- W3101767498 hasConcept C11804247 @default.
- W3101767498 hasConcept C12554922 @default.
- W3101767498 hasConcept C126725582 @default.
- W3101767498 hasConcept C185592680 @default.
- W3101767498 hasConcept C190062978 @default.
- W3101767498 hasConcept C2778815515 @default.
- W3101767498 hasConcept C2780557392 @default.
- W3101767498 hasConcept C41008148 @default.
- W3101767498 hasConcept C51639874 @default.
- W3101767498 hasConcept C70721500 @default.
- W3101767498 hasConcept C86803240 @default.
- W3101767498 hasConcept C95444343 @default.
- W3101767498 hasConceptScore W3101767498C111919701 @default.
- W3101767498 hasConceptScore W3101767498C11804247 @default.
- W3101767498 hasConceptScore W3101767498C12554922 @default.
- W3101767498 hasConceptScore W3101767498C126725582 @default.