Matches in SemOpenAlex for { <https://semopenalex.org/work/W3102199880> ?p ?o ?g. }
- W3102199880 endingPage "3654" @default.
- W3102199880 startingPage "3654" @default.
- W3102199880 abstract "Cerebellar ataxias (CAs) are neurological diseases characterized by loss of muscle coordination that is a result of damage and inflammation to the cerebellum. Despite considerable efforts in basic and clinical research, most CAs are currently incurable. In this study, we evaluated the therapeutic potential of human mesenchymal stem cells (hMSCs) against CAs associated with neuroinflammation. We observed that hMSC treatment significantly inhibited the symptoms of ataxia in lipopolysaccharide (LPS)-induced inflammatory CA (ICA) mice, which were recently reported as a potential animal model of ICA, through the anti-inflammatory effect of hMSC-derived TNFα-stimulated gene-6 (TSG-6), the protection of Purkinje cells by inhibition of apoptosis, and the modulatory effect for microglial M2 polarization. Thus, our results suggest that hMSC treatment may be an effective therapeutic approach for preventing or improving ataxia symptoms." @default.
- W3102199880 created "2020-11-23" @default.
- W3102199880 creator A5012166447 @default.
- W3102199880 creator A5012866137 @default.
- W3102199880 creator A5040972996 @default.
- W3102199880 creator A5067566788 @default.
- W3102199880 creator A5079808024 @default.
- W3102199880 creator A5081581544 @default.
- W3102199880 creator A5085119210 @default.
- W3102199880 creator A5085159256 @default.
- W3102199880 creator A5086053205 @default.
- W3102199880 date "2020-11-13" @default.
- W3102199880 modified "2023-10-16" @default.
- W3102199880 title "Therapeutic Effects of Human Mesenchymal Stem Cells in a Mouse Model of Cerebellar Ataxia with Neuroinflammation" @default.
- W3102199880 cites W1190602094 @default.
- W3102199880 cites W1599751493 @default.
- W3102199880 cites W1698980491 @default.
- W3102199880 cites W1854525373 @default.
- W3102199880 cites W1947057196 @default.
- W3102199880 cites W1956862481 @default.
- W3102199880 cites W1963720308 @default.
- W3102199880 cites W1967338396 @default.
- W3102199880 cites W1968456568 @default.
- W3102199880 cites W1974397700 @default.
- W3102199880 cites W1980424869 @default.
- W3102199880 cites W1982789137 @default.
- W3102199880 cites W1989126478 @default.
- W3102199880 cites W1991201653 @default.
- W3102199880 cites W1991430538 @default.
- W3102199880 cites W1996161359 @default.
- W3102199880 cites W2017555154 @default.
- W3102199880 cites W2021916724 @default.
- W3102199880 cites W2025371271 @default.
- W3102199880 cites W2028702444 @default.
- W3102199880 cites W2035922700 @default.
- W3102199880 cites W2047793388 @default.
- W3102199880 cites W2056315364 @default.
- W3102199880 cites W2069893872 @default.
- W3102199880 cites W2081287867 @default.
- W3102199880 cites W2093580086 @default.
- W3102199880 cites W2098934468 @default.
- W3102199880 cites W2099040590 @default.
- W3102199880 cites W2105313624 @default.
- W3102199880 cites W2106482753 @default.
- W3102199880 cites W2106647511 @default.
- W3102199880 cites W2113619226 @default.
- W3102199880 cites W2135652919 @default.
- W3102199880 cites W2140890859 @default.
- W3102199880 cites W2147180300 @default.
- W3102199880 cites W2147299630 @default.
- W3102199880 cites W2156509094 @default.
- W3102199880 cites W2159073672 @default.
- W3102199880 cites W2164068801 @default.
- W3102199880 cites W2167348059 @default.
- W3102199880 cites W2171800376 @default.
- W3102199880 cites W2206359149 @default.
- W3102199880 cites W2301259598 @default.
- W3102199880 cites W2340149296 @default.
- W3102199880 cites W2365662975 @default.
- W3102199880 cites W2436616643 @default.
- W3102199880 cites W2469169643 @default.
- W3102199880 cites W2503929025 @default.
- W3102199880 cites W2516789676 @default.
- W3102199880 cites W2528456374 @default.
- W3102199880 cites W2557343579 @default.
- W3102199880 cites W2766892665 @default.
- W3102199880 cites W2783235617 @default.
- W3102199880 cites W2784326810 @default.
- W3102199880 cites W2884533127 @default.
- W3102199880 cites W2888711295 @default.
- W3102199880 cites W2943027232 @default.
- W3102199880 cites W2972152929 @default.
- W3102199880 cites W3047712711 @default.
- W3102199880 cites W3141559369 @default.
- W3102199880 doi "https://doi.org/10.3390/jcm9113654" @default.
- W3102199880 hasPubMedCentralId "https://www.ncbi.nlm.nih.gov/pmc/articles/7698164" @default.
- W3102199880 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/33202913" @default.
- W3102199880 hasPublicationYear "2020" @default.
- W3102199880 type Work @default.
- W3102199880 sameAs 3102199880 @default.
- W3102199880 citedByCount "5" @default.
- W3102199880 countsByYear W31021998802021 @default.
- W3102199880 countsByYear W31021998802023 @default.
- W3102199880 crossrefType "journal-article" @default.
- W3102199880 hasAuthorship W3102199880A5012166447 @default.
- W3102199880 hasAuthorship W3102199880A5012866137 @default.
- W3102199880 hasAuthorship W3102199880A5040972996 @default.
- W3102199880 hasAuthorship W3102199880A5067566788 @default.
- W3102199880 hasAuthorship W3102199880A5079808024 @default.
- W3102199880 hasAuthorship W3102199880A5081581544 @default.
- W3102199880 hasAuthorship W3102199880A5085119210 @default.
- W3102199880 hasAuthorship W3102199880A5085159256 @default.
- W3102199880 hasAuthorship W3102199880A5086053205 @default.
- W3102199880 hasBestOaLocation W31021998801 @default.
- W3102199880 hasConcept C102652120 @default.
- W3102199880 hasConcept C118552586 @default.
- W3102199880 hasConcept C126322002 @default.
- W3102199880 hasConcept C142724271 @default.