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- W3102403167 abstract "Abstract Background Depressive and anxiety disorders are highly comorbid, which has been theorized to be due to an underlying internalizing vulnerability. We aimed to identify groups of participants with differing vulnerabilities by examining the course of internalizing psychopathology up to age 45. Methods We used data from 24158 participants (aged 45+) in 23 population-based cross-sectional World Mental Health Surveys. Internalizing disorders were assessed with the Composite International Diagnostic Interview (CIDI). We applied latent class growth analysis (LCGA) and investigated the characteristics of identified classes using logistic or linear regression. Results The best-fitting LCGA solution identified eight classes: a healthy class (81.9%), three childhood-onset classes with mild (3.7%), moderate (2.0%), or severe (1.1%) internalizing comorbidity, two puberty-onset classes with mild (4.0%) or moderate (1.4%) comorbidity, and two adult-onset classes with mild comorbidity (2.7% and 3.2%). The childhood-onset severe class had particularly unfavorable sociodemographic outcomes compared to the healthy class, with increased risks of being never or previously married (OR = 2.2 and 2.0, p < 0.001), not being employed (OR = 3.5, p < 0.001), and having a low/low-average income (OR = 2.2, p < 0.001). Moderate or severe ( v . mild) comorbidity was associated with 12-month internalizing disorders (OR = 1.9 and 4.8, p < 0.001), disability (B = 1.1–2.3, p < 0.001), and suicidal ideation (OR = 4.2, p < 0.001 for severe comorbidity only). Adult ( v . childhood) onset was associated with lower rates of 12-month internalizing disorders (OR = 0.2, p < 0.001). Conclusions We identified eight transdiagnostic trajectories of internalizing psychopathology. Unfavorable outcomes were concentrated in the 1% of participants with childhood onset and severe comorbidity. Early identification of this group may offer opportunities for preventive interventions." @default.
- W3102403167 created "2020-11-23" @default.
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- W3102403167 date "2020-11-10" @default.
- W3102403167 modified "2023-10-06" @default.
- W3102403167 title "Transdiagnostic development of internalizing psychopathology throughout the life course up to age 45: a World Mental Health Surveys report" @default.
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- W3102403167 cites W2027716777 @default.
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- W3102403167 cites W2041408842 @default.
- W3102403167 cites W2042371963 @default.
- W3102403167 cites W2048968986 @default.
- W3102403167 cites W2061625978 @default.
- W3102403167 cites W2073661387 @default.
- W3102403167 cites W2074503869 @default.
- W3102403167 cites W2094995137 @default.
- W3102403167 cites W2095510225 @default.
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- W3102403167 cites W2117410001 @default.
- W3102403167 cites W2118225566 @default.
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- W3102403167 cites W2162510673 @default.
- W3102403167 cites W2162994164 @default.
- W3102403167 cites W2164855913 @default.
- W3102403167 cites W2170684975 @default.
- W3102403167 cites W2297262337 @default.
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- W3102403167 doi "https://doi.org/10.1017/s0033291720004031" @default.
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