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- W3102410312 endingPage "367" @default.
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- W3102410312 abstract "Blast brain injury (bBI) is a combination of several forces of pressure, rotation, penetration of sharp objects and chemical exposure causing laceration, perforation and tissue losses in the brain. The bBI is quite prevalent in military personnel during combat operations. However, no suitable therapeutic strategies are available so far to minimize bBI pathology. Combat stress induces profound cardiovascular and endocrine dysfunction leading to psychosomatic disorders including diabetes mellitus (DM). This is still unclear whether brain pathology in bBI could exacerbate in DM. In present review influence of DM on pathophysiology of bBI is discussed based on our own investigations. In addition, treatment with cerebrolysin (a multimodal drug comprising neurotrophic factors and active peptide fragments) or H-290/51 (a chain-breaking antioxidant) using nanowired delivery of for superior neuroprotection on brain pathology in bBI in DM is explored. Our observations are the first to show that pathophysiology of bBI is exacerbated in DM and TiO2-nanowired delivery of cerebrolysin induces profound neuroprotection in bBI in DM, not reported earlier. The clinical significance of our findings with regard to military medicine is discussed." @default.
- W3102410312 created "2020-11-23" @default.
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- W3102410312 date "2020-01-01" @default.
- W3102410312 modified "2023-10-18" @default.
- W3102410312 title "Diabetes exacerbates brain pathology following a focal blast brain injury: New role of a multimodal drug cerebrolysin and nanomedicine" @default.
- W3102410312 cites W1162628701 @default.
- W3102410312 cites W120823498 @default.
- W3102410312 cites W129468013 @default.
- W3102410312 cites W1453012560 @default.
- W3102410312 cites W1486425129 @default.
- W3102410312 cites W1488400941 @default.
- W3102410312 cites W1490148623 @default.
- W3102410312 cites W1491790392 @default.
- W3102410312 cites W1512007375 @default.
- W3102410312 cites W1527714022 @default.
- W3102410312 cites W1529163965 @default.
- W3102410312 cites W1555943076 @default.
- W3102410312 cites W155638485 @default.
- W3102410312 cites W1564669112 @default.
- W3102410312 cites W1568806992 @default.
- W3102410312 cites W1583262546 @default.
- W3102410312 cites W1590073716 @default.
- W3102410312 cites W1601347600 @default.
- W3102410312 cites W160617621 @default.
- W3102410312 cites W1645350431 @default.
- W3102410312 cites W166795620 @default.
- W3102410312 cites W1794038664 @default.
- W3102410312 cites W1833535161 @default.
- W3102410312 cites W1847168837 @default.
- W3102410312 cites W1888971219 @default.
- W3102410312 cites W1899006197 @default.
- W3102410312 cites W1911548173 @default.
- W3102410312 cites W1915763889 @default.
- W3102410312 cites W1941737414 @default.
- W3102410312 cites W1944647947 @default.
- W3102410312 cites W1945195170 @default.
- W3102410312 cites W1965502941 @default.
- W3102410312 cites W1966466547 @default.
- W3102410312 cites W1967789041 @default.
- W3102410312 cites W1967861550 @default.
- W3102410312 cites W1968986410 @default.
- W3102410312 cites W1969533028 @default.
- W3102410312 cites W1970665848 @default.
- W3102410312 cites W1971364857 @default.
- W3102410312 cites W1971377483 @default.
- W3102410312 cites W1972042882 @default.
- W3102410312 cites W1972076726 @default.
- W3102410312 cites W1972695634 @default.
- W3102410312 cites W1972990255 @default.
- W3102410312 cites W1973919236 @default.
- W3102410312 cites W1976482767 @default.
- W3102410312 cites W1976967181 @default.
- W3102410312 cites W1977398898 @default.
- W3102410312 cites W1979872582 @default.
- W3102410312 cites W1981910546 @default.
- W3102410312 cites W1982685226 @default.
- W3102410312 cites W1984800913 @default.
- W3102410312 cites W1984971429 @default.
- W3102410312 cites W1985973070 @default.
- W3102410312 cites W1986144413 @default.
- W3102410312 cites W1987682444 @default.
- W3102410312 cites W1988251362 @default.
- W3102410312 cites W1988761237 @default.
- W3102410312 cites W1989138409 @default.
- W3102410312 cites W1989290237 @default.
- W3102410312 cites W1990423532 @default.
- W3102410312 cites W1990887043 @default.
- W3102410312 cites W1991628249 @default.
- W3102410312 cites W1991953639 @default.
- W3102410312 cites W1995941794 @default.
- W3102410312 cites W1996212130 @default.
- W3102410312 cites W1996388418 @default.
- W3102410312 cites W1996504766 @default.
- W3102410312 cites W1999311858 @default.
- W3102410312 cites W2000928112 @default.
- W3102410312 cites W2001068966 @default.
- W3102410312 cites W2003106438 @default.
- W3102410312 cites W2004276842 @default.
- W3102410312 cites W2004314307 @default.
- W3102410312 cites W2005343296 @default.
- W3102410312 cites W2006184260 @default.
- W3102410312 cites W2006423906 @default.
- W3102410312 cites W2007556598 @default.
- W3102410312 cites W2008154014 @default.
- W3102410312 cites W2008215562 @default.