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- W3102445490 abstract "Pm1a, the first powdery mildew resistance gene described in wheat, is part of a complex resistance (R) gene cluster located in a distal region of chromosome 7AL that has suppressed genetic recombination. A nucleotide-binding, leucine-rich repeat (NLR) immune receptor gene was isolated using mutagenesis and R gene enrichment sequencing (MutRenSeq). Stable transformation confirmed Pm1a identity which induced a strong resistance phenotype in transgenic plants upon challenge with avirulent Blumeria graminis (wheat powdery mildew) pathogens. A high-density genetic map of a B. graminis family segregating for Pm1a avirulence combined with pathogen genome resequencing and RNA sequencing (RNAseq) identified AvrPm1a effector gene candidates. In planta expression identified an effector, with an N terminal Y/FxC motif, that induced a strong hypersensitive response when co-expressed with Pm1a in Nicotiana benthamiana. Single chromosome enrichment sequencing (ChromSeq) and assembly of chromosome 7A suggested that suppressed recombination around the Pm1a region was due to a rearrangement involving chromosomes 7A, 7B and 7D. The cloning of Pm1a and its identification in a highly rearranged region of chromosome 7A provides insight into the role of chromosomal rearrangements in the evolution of this complex resistance cluster." @default.
- W3102445490 created "2020-11-23" @default.
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- W3102445490 date "2020-12-15" @default.
- W3102445490 modified "2023-10-16" @default.
- W3102445490 title "A highly differentiated region of wheat chromosome 7AL encodes a <i>Pm1a</i> immune receptor that recognizes its corresponding <i>AvrPm1a</i> effector from <i>Blumeria graminis</i>" @default.
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- W3102445490 cites W1968518021 @default.
- W3102445490 cites W1976599737 @default.
- W3102445490 cites W1977754479 @default.
- W3102445490 cites W1978104274 @default.
- W3102445490 cites W1985270286 @default.
- W3102445490 cites W2003127518 @default.
- W3102445490 cites W2014246647 @default.
- W3102445490 cites W2016727462 @default.
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- W3102445490 cites W2055666215 @default.
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- W3102445490 cites W2093738033 @default.
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- W3102445490 cites W2108234281 @default.
- W3102445490 cites W2114104545 @default.
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- W3102445490 cites W2161746138 @default.
- W3102445490 cites W2169456326 @default.
- W3102445490 cites W2184462349 @default.
- W3102445490 cites W2252663341 @default.
- W3102445490 cites W2274713094 @default.
- W3102445490 cites W2287227998 @default.
- W3102445490 cites W2320195605 @default.
- W3102445490 cites W2342514051 @default.
- W3102445490 cites W2418223933 @default.
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- W3102445490 cites W2592811885 @default.
- W3102445490 cites W2743070295 @default.
- W3102445490 cites W2767274656 @default.
- W3102445490 cites W2781452132 @default.
- W3102445490 cites W2791912122 @default.
- W3102445490 cites W2792078902 @default.
- W3102445490 cites W2793646840 @default.
- W3102445490 cites W2794290719 @default.
- W3102445490 cites W2794441222 @default.
- W3102445490 cites W2799524357 @default.
- W3102445490 cites W2886785109 @default.
- W3102445490 cites W2888268014 @default.
- W3102445490 cites W2892689606 @default.
- W3102445490 cites W2894249078 @default.
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- W3102445490 doi "https://doi.org/10.1111/nph.17075" @default.
- W3102445490 hasPubMedCentralId "https://www.ncbi.nlm.nih.gov/pmc/articles/8022591" @default.
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- W3102445490 hasPublicationYear "2020" @default.
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