Matches in SemOpenAlex for { <https://semopenalex.org/work/W3102609266> ?p ?o ?g. }
- W3102609266 endingPage "1193" @default.
- W3102609266 startingPage "1179" @default.
- W3102609266 abstract "The search for effective coronavirus disease (COVID-19) therapy has attracted a great deal of scientific interest due to its unprecedented health care system overload worldwide. We have carried out a study to investigate the in silico effects of the most abundant pomegranate peel extract constituents on the multi-step process of serious acute respiratory syndrome coronavirus 2 (SARS-CoV-2) internalization in the host cells. Binding affinities and interactions of ellagic acid, gallic acid, punicalagin and punicalin were studied on four selected protein targets with a significant and confirmed role in the process of the entry of virus into a host cell. The protein targets used in this study were: SARS-CoV-2 spike glycoprotein, angiotensin-converting enzyme 2, furin and transmembrane serine protease 2. The results showed that the constituents of pomegranate peel extracts, namely punicalagin and punicalin had very promising potential for significant interactions with the selected protein targets and were therefore deemed good candidates for further in vitro and in vivo evaluation." @default.
- W3102609266 created "2020-11-23" @default.
- W3102609266 creator A5036581874 @default.
- W3102609266 creator A5048623628 @default.
- W3102609266 creator A5049595446 @default.
- W3102609266 creator A5059073754 @default.
- W3102609266 creator A5062739437 @default.
- W3102609266 creator A5063393755 @default.
- W3102609266 creator A5086466711 @default.
- W3102609266 creator A5089050991 @default.
- W3102609266 date "2020-11-16" @default.
- W3102609266 modified "2023-10-01" @default.
- W3102609266 title "Computational study of pomegranate peel extract polyphenols as potential inhibitors of SARS-CoV-2 virus internalization" @default.
- W3102609266 cites W1970799005 @default.
- W3102609266 cites W1971066657 @default.
- W3102609266 cites W1981064967 @default.
- W3102609266 cites W1996452779 @default.
- W3102609266 cites W2018347389 @default.
- W3102609266 cites W2038226280 @default.
- W3102609266 cites W2065807927 @default.
- W3102609266 cites W2084536885 @default.
- W3102609266 cites W2085324736 @default.
- W3102609266 cites W2086625083 @default.
- W3102609266 cites W2094806587 @default.
- W3102609266 cites W2095331561 @default.
- W3102609266 cites W2101973479 @default.
- W3102609266 cites W2119944195 @default.
- W3102609266 cites W2134967712 @default.
- W3102609266 cites W2140407975 @default.
- W3102609266 cites W2157111076 @default.
- W3102609266 cites W2158419579 @default.
- W3102609266 cites W2222375237 @default.
- W3102609266 cites W2470646526 @default.
- W3102609266 cites W2575521580 @default.
- W3102609266 cites W2751079439 @default.
- W3102609266 cites W2789099305 @default.
- W3102609266 cites W2803852489 @default.
- W3102609266 cites W2899885689 @default.
- W3102609266 cites W2906486865 @default.
- W3102609266 cites W2976349502 @default.
- W3102609266 cites W2980001212 @default.
- W3102609266 cites W2994116301 @default.
- W3102609266 cites W3007643904 @default.
- W3102609266 cites W3008142620 @default.
- W3102609266 cites W3009577418 @default.
- W3102609266 cites W3009906937 @default.
- W3102609266 cites W3009912996 @default.
- W3102609266 cites W3011398105 @default.
- W3102609266 cites W3011483298 @default.
- W3102609266 cites W3011537081 @default.
- W3102609266 cites W3011959119 @default.
- W3102609266 cites W3012492786 @default.
- W3102609266 cites W3013359483 @default.
- W3102609266 cites W3013525829 @default.
- W3102609266 cites W3015134137 @default.
- W3102609266 cites W3015490759 @default.
- W3102609266 cites W3015769528 @default.
- W3102609266 cites W3016553966 @default.
- W3102609266 cites W3016726004 @default.
- W3102609266 cites W3017302293 @default.
- W3102609266 cites W3017331996 @default.
- W3102609266 cites W3023248186 @default.
- W3102609266 cites W3043035864 @default.
- W3102609266 cites W3043773321 @default.
- W3102609266 cites W3091244312 @default.
- W3102609266 cites W3109099678 @default.
- W3102609266 cites W3201200939 @default.
- W3102609266 cites W4238332960 @default.
- W3102609266 doi "https://doi.org/10.1007/s11010-020-03981-7" @default.
- W3102609266 hasPubMedCentralId "https://www.ncbi.nlm.nih.gov/pmc/articles/7668668" @default.
- W3102609266 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/33200379" @default.
- W3102609266 hasPublicationYear "2020" @default.
- W3102609266 type Work @default.
- W3102609266 sameAs 3102609266 @default.
- W3102609266 citedByCount "37" @default.
- W3102609266 countsByYear W31026092662021 @default.
- W3102609266 countsByYear W31026092662022 @default.
- W3102609266 countsByYear W31026092662023 @default.
- W3102609266 crossrefType "journal-article" @default.
- W3102609266 hasAuthorship W3102609266A5036581874 @default.
- W3102609266 hasAuthorship W3102609266A5048623628 @default.
- W3102609266 hasAuthorship W3102609266A5049595446 @default.
- W3102609266 hasAuthorship W3102609266A5059073754 @default.
- W3102609266 hasAuthorship W3102609266A5062739437 @default.
- W3102609266 hasAuthorship W3102609266A5063393755 @default.
- W3102609266 hasAuthorship W3102609266A5086466711 @default.
- W3102609266 hasAuthorship W3102609266A5089050991 @default.
- W3102609266 hasBestOaLocation W31026092661 @default.
- W3102609266 hasConcept C104317684 @default.
- W3102609266 hasConcept C139770010 @default.
- W3102609266 hasConcept C142724271 @default.
- W3102609266 hasConcept C1491633281 @default.
- W3102609266 hasConcept C159047783 @default.
- W3102609266 hasConcept C181199279 @default.
- W3102609266 hasConcept C182220744 @default.
- W3102609266 hasConcept C185592680 @default.
- W3102609266 hasConcept C2522874641 @default.
- W3102609266 hasConcept C2775881703 @default.