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• W3102752510 abstract "High-dose-rate brachytherapy is a tumor treatment method where a highly radioactive source is brought in close proximity to the tumor. In this paper we develop a simulated annealing algorithm to optimize the dwell times at preselected dwell positions to maximize tumor coverage under dose-volume constraints on the organs at risk. Compared to existing algorithms, our algorithm has advantages in terms of speed and objective value and does not require an expensive general purpose solver. Its success mainly depends on exploiting the efficiency of matrix multiplication and a careful selection of the neighboring states. In this paper we outline its details and make an in-depth comparison with existing methods using real patient data." @default.
• W3102752510 created "2020-11-23" @default.
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• W3102752510 date "2016-01-13" @default.
• W3102752510 modified "2023-10-16" @default.
• W3102752510 title "High-dose-rate prostate brachytherapy inverse planning on dose-volume criteria by simulated annealing" @default.
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• W3102752510 doi "https://doi.org/10.1088/0031-9155/61/3/1155" @default.
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