Matches in SemOpenAlex for { <https://semopenalex.org/work/W3102767542> ?p ?o ?g. }
- W3102767542 endingPage "1035" @default.
- W3102767542 startingPage "1027" @default.
- W3102767542 abstract "Abstract Objective Social engagement (SE) may protect against cognitive decline in older adults. We estimate associations of SE with gray matter (GM) microstructure in regions of interest (ROI) relevant to social cognition, among community-dwelling older adults. Method Cross-sectional analysis of 293 Health ABC study participants who underwent 3 Tesla magnetic resonance imaging with diffusion tensor and free from cognitive impairment was conducted. Linear regression models tested associations between SE index (marital status, not living alone, social activities, work, and volunteering) and mean diffusivity (MD) of GM ROIs, adjusted for age, race, gender, and education. Hearing and activities of daily living (ADL) difficulties were tested as confounders. Effect modification by gender was tested with interaction terms and stratification by gender. Results Higher SE was significantly related to lower MD (greater GM microstructural integrity) (shown as standardized estimate [p-value]) in left middle frontal gyrus-orbital part: −.168 (.005), left caudate nucleus: −.141 (.02), left temporal pole-middle temporal gyrus: −.136 (.03), right middle frontal gyrus: −.160 (.006), right superior frontal gyrus-orbital part: −.187 (.002), and right middle frontal gyrus-orbital part: −.124 (.04), when adjusted for demographic attributes. Associations were robust to adjustments for hearing or ADL difficulty. There was significant effect modification by gender for some ROIs, with associations only for females. Discussion SE is related to greater microstructural integrity of specific GM regions relevant to social cognition, that have described roles in dementia. SE may therefore be a useful preventive mechanism against loss of GM integrity in older adults." @default.
- W3102767542 created "2020-11-23" @default.
- W3102767542 creator A5006407762 @default.
- W3102767542 creator A5011086268 @default.
- W3102767542 creator A5022626072 @default.
- W3102767542 creator A5076241114 @default.
- W3102767542 creator A5087201620 @default.
- W3102767542 date "2020-10-19" @default.
- W3102767542 modified "2023-10-15" @default.
- W3102767542 title "Greater Social Engagement and Greater Gray Matter Microstructural Integrity in Brain Regions Relevant to Dementia" @default.
- W3102767542 cites W1820863330 @default.
- W3102767542 cites W1929876078 @default.
- W3102767542 cites W1975566892 @default.
- W3102767542 cites W2004006028 @default.
- W3102767542 cites W2015667343 @default.
- W3102767542 cites W2019240982 @default.
- W3102767542 cites W2027853020 @default.
- W3102767542 cites W2034232242 @default.
- W3102767542 cites W2037855378 @default.
- W3102767542 cites W2046959837 @default.
- W3102767542 cites W2058046532 @default.
- W3102767542 cites W2073441380 @default.
- W3102767542 cites W2080439255 @default.
- W3102767542 cites W2087431174 @default.
- W3102767542 cites W2093650784 @default.
- W3102767542 cites W2099720770 @default.
- W3102767542 cites W2106159603 @default.
- W3102767542 cites W2106649637 @default.
- W3102767542 cites W2111046480 @default.
- W3102767542 cites W2112778345 @default.
- W3102767542 cites W2116794070 @default.
- W3102767542 cites W2121354731 @default.
- W3102767542 cites W2122522567 @default.
- W3102767542 cites W2123719421 @default.
- W3102767542 cites W2126080113 @default.
- W3102767542 cites W2128648170 @default.
- W3102767542 cites W2131286474 @default.
- W3102767542 cites W2133674973 @default.
- W3102767542 cites W2141466480 @default.
- W3102767542 cites W2144699140 @default.
- W3102767542 cites W2146068507 @default.
- W3102767542 cites W2245343745 @default.
- W3102767542 cites W2317889588 @default.
- W3102767542 cites W2604288732 @default.
- W3102767542 cites W2756641284 @default.
- W3102767542 cites W2763764317 @default.
- W3102767542 cites W2802476177 @default.
- W3102767542 cites W2896003083 @default.
- W3102767542 cites W2900735327 @default.
- W3102767542 cites W2919786092 @default.
- W3102767542 cites W2958401142 @default.
- W3102767542 cites W2965550158 @default.
- W3102767542 cites W2974655760 @default.
- W3102767542 cites W2982303627 @default.
- W3102767542 cites W2995456142 @default.
- W3102767542 doi "https://doi.org/10.1093/geronb/gbaa173" @default.
- W3102767542 hasPubMedCentralId "https://www.ncbi.nlm.nih.gov/pmc/articles/8200358" @default.
- W3102767542 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/33219690" @default.
- W3102767542 hasPublicationYear "2020" @default.
- W3102767542 type Work @default.
- W3102767542 sameAs 3102767542 @default.
- W3102767542 citedByCount "10" @default.
- W3102767542 countsByYear W31027675422021 @default.
- W3102767542 countsByYear W31027675422022 @default.
- W3102767542 countsByYear W31027675422023 @default.
- W3102767542 crossrefType "journal-article" @default.
- W3102767542 hasAuthorship W3102767542A5006407762 @default.
- W3102767542 hasAuthorship W3102767542A5011086268 @default.
- W3102767542 hasAuthorship W3102767542A5022626072 @default.
- W3102767542 hasAuthorship W3102767542A5076241114 @default.
- W3102767542 hasAuthorship W3102767542A5087201620 @default.
- W3102767542 hasBestOaLocation W31027675421 @default.
- W3102767542 hasConcept C118552586 @default.
- W3102767542 hasConcept C126322002 @default.
- W3102767542 hasConcept C126838900 @default.
- W3102767542 hasConcept C15744967 @default.
- W3102767542 hasConcept C166275286 @default.
- W3102767542 hasConcept C169900460 @default.
- W3102767542 hasConcept C2779134260 @default.
- W3102767542 hasConcept C2779483572 @default.
- W3102767542 hasConcept C548259974 @default.
- W3102767542 hasConcept C70410870 @default.
- W3102767542 hasConcept C71924100 @default.
- W3102767542 hasConcept C74909509 @default.
- W3102767542 hasConcept C77350462 @default.
- W3102767542 hasConceptScore W3102767542C118552586 @default.
- W3102767542 hasConceptScore W3102767542C126322002 @default.
- W3102767542 hasConceptScore W3102767542C126838900 @default.
- W3102767542 hasConceptScore W3102767542C15744967 @default.
- W3102767542 hasConceptScore W3102767542C166275286 @default.
- W3102767542 hasConceptScore W3102767542C169900460 @default.
- W3102767542 hasConceptScore W3102767542C2779134260 @default.
- W3102767542 hasConceptScore W3102767542C2779483572 @default.
- W3102767542 hasConceptScore W3102767542C548259974 @default.
- W3102767542 hasConceptScore W3102767542C70410870 @default.
- W3102767542 hasConceptScore W3102767542C71924100 @default.
- W3102767542 hasConceptScore W3102767542C74909509 @default.
- W3102767542 hasConceptScore W3102767542C77350462 @default.