Matches in SemOpenAlex for { <https://semopenalex.org/work/W3102829381> ?p ?o ?g. }
- W3102829381 endingPage "17" @default.
- W3102829381 startingPage "1" @default.
- W3102829381 abstract "(E)-N,N-Dimethyl-2-((E-1-(2-(p-tolyl)hydrazono)propan-2-ylidene)hydrazine-1-carbothioamide (DMPTHP) and their Zn(II) and Cd(II) complexes have been synthesized and characterized. Different tools of analysis such as elemental analyses, IR, mass spectra, and 1H-NMR measurements were used to elucidate the structure of the synthesized compounds. According to these spectral results, the DMPTHP ligand behaved as a mononegatively charged tridentate anion. Modeling and docking studies were investigated and discussed. Novel Schiff base (DMPTHP) ligand protonation constants and their formation constants with Cd(II) and Zn(II) ions were measured in 50% DMSO solution at 15°C, 25°C, and 35°C at I = 0.1 mol·dm−3 NaNO3. The solution speciation of different species was measured in accordance with pH. Calculation and discussion of the thermodynamic parameters were achieved. Both log K1 and –ΔH1, for M(II)-thiosemicarbazone complexes were found to be somewhat larger than log K2 and –ΔH2, demonstrating a shift in the dentate character of DMPTHP from tridentate in 1 : 1 chelates to bidentate in 1 : 2; M : L chelates and steric hindrance were generated by addition of the 2nd molecule. The compounds prepared have significant activity as antioxidants, similar to ascorbic acid. It is hoped that the results will be beneficial to antimicrobial agent chemistry. The formed compounds acted as a potent antibacterial agent. Molecular docking studies were investigated and have proved that DMPTHP as antibacterial agents act on highly resistant strains of E. coli and also as an anticancer agent." @default.
- W3102829381 created "2020-11-23" @default.
- W3102829381 creator A5003257162 @default.
- W3102829381 creator A5022879199 @default.
- W3102829381 date "2020-11-18" @default.
- W3102829381 modified "2023-10-14" @default.
- W3102829381 title "Synthesis and Biological Evaluation of Novel Zn(II) and Cd(II) Schiff Base Complexes as Antimicrobial, Antifungal, and Antioxidant Agents" @default.
- W3102829381 cites W116586914 @default.
- W3102829381 cites W1966436040 @default.
- W3102829381 cites W1966750682 @default.
- W3102829381 cites W1969508979 @default.
- W3102829381 cites W1977085692 @default.
- W3102829381 cites W1978718023 @default.
- W3102829381 cites W1983657762 @default.
- W3102829381 cites W1983783092 @default.
- W3102829381 cites W1985239021 @default.
- W3102829381 cites W1985552765 @default.
- W3102829381 cites W1990620820 @default.
- W3102829381 cites W1991149034 @default.
- W3102829381 cites W1991767477 @default.
- W3102829381 cites W1998102079 @default.
- W3102829381 cites W1998722626 @default.
- W3102829381 cites W2004765672 @default.
- W3102829381 cites W2008228075 @default.
- W3102829381 cites W2008470511 @default.
- W3102829381 cites W2008630817 @default.
- W3102829381 cites W2008708918 @default.
- W3102829381 cites W2014286678 @default.
- W3102829381 cites W2016000773 @default.
- W3102829381 cites W2016814099 @default.
- W3102829381 cites W2018069090 @default.
- W3102829381 cites W2019642430 @default.
- W3102829381 cites W2022879319 @default.
- W3102829381 cites W2023233464 @default.
- W3102829381 cites W2027488304 @default.
- W3102829381 cites W2034351519 @default.
- W3102829381 cites W2034676594 @default.
- W3102829381 cites W2041450584 @default.
- W3102829381 cites W2046573323 @default.
- W3102829381 cites W2048024271 @default.
- W3102829381 cites W2050477319 @default.
- W3102829381 cites W2051597769 @default.
- W3102829381 cites W2051598371 @default.
- W3102829381 cites W2053933453 @default.
- W3102829381 cites W2056024208 @default.
- W3102829381 cites W2059855508 @default.
- W3102829381 cites W2060910349 @default.
- W3102829381 cites W2063234855 @default.
- W3102829381 cites W2063436512 @default.
- W3102829381 cites W2066509288 @default.
- W3102829381 cites W2067302072 @default.
- W3102829381 cites W2070458959 @default.
- W3102829381 cites W2072922607 @default.
- W3102829381 cites W2073958882 @default.
- W3102829381 cites W2079277250 @default.
- W3102829381 cites W2080323232 @default.
- W3102829381 cites W2080944802 @default.
- W3102829381 cites W2084537823 @default.
- W3102829381 cites W2093856947 @default.
- W3102829381 cites W2094103382 @default.
- W3102829381 cites W2101958915 @default.
- W3102829381 cites W2107219837 @default.
- W3102829381 cites W2120279316 @default.
- W3102829381 cites W2121399115 @default.
- W3102829381 cites W2121669287 @default.
- W3102829381 cites W2133183504 @default.
- W3102829381 cites W2136931384 @default.
- W3102829381 cites W2141535516 @default.
- W3102829381 cites W2143295328 @default.
- W3102829381 cites W2147822570 @default.
- W3102829381 cites W2171515128 @default.
- W3102829381 cites W2503005323 @default.
- W3102829381 cites W2801002516 @default.
- W3102829381 cites W2898237177 @default.
- W3102829381 cites W3009840675 @default.
- W3102829381 cites W3100706582 @default.
- W3102829381 cites W4231649355 @default.
- W3102829381 cites W4246538139 @default.
- W3102829381 doi "https://doi.org/10.1155/2020/8866382" @default.
- W3102829381 hasPublicationYear "2020" @default.
- W3102829381 type Work @default.
- W3102829381 sameAs 3102829381 @default.
- W3102829381 citedByCount "8" @default.
- W3102829381 countsByYear W31028293812021 @default.
- W3102829381 countsByYear W31028293812022 @default.
- W3102829381 countsByYear W31028293812023 @default.
- W3102829381 crossrefType "journal-article" @default.
- W3102829381 hasAuthorship W3102829381A5003257162 @default.
- W3102829381 hasAuthorship W3102829381A5022879199 @default.
- W3102829381 hasBestOaLocation W31028293811 @default.
- W3102829381 hasConcept C116569031 @default.
- W3102829381 hasConcept C145148216 @default.
- W3102829381 hasConcept C155647269 @default.
- W3102829381 hasConcept C168191866 @default.
- W3102829381 hasConcept C170493617 @default.
- W3102829381 hasConcept C178516000 @default.
- W3102829381 hasConcept C178790620 @default.
- W3102829381 hasConcept C185592680 @default.