FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W3103113323> ?p ?o ?g. }

• W3103113323 endingPage "84" @default.
• W3103113323 startingPage "84" @default.
• W3103113323 abstract "Background: pH is increasingly a target in therapeutic strategies for skin barrier repair, but the relationship between pH, transepidermal water loss (TEWL), and atopic dermatitis (AD) severity is not well characterized. Purpose: The purpose of the study was to determine the relationship between skin pH with TEWL and their correlations with AD severity. Methods: A cross-sectional study enrolled children aged 4–12 years with AD. Measurements were made using HI 99181 and Tewameter TM 300 at two lesional sites and two nonlesional sites (left cubital fossa, left thigh, and forehead). Disease severity was evaluated using the Eczema Area and Severity Index (EASI) and pruritus score. Results: A total of 14 (58%) girls and 10 (42%) boys aged 7.3 ± 2.6 years with age of AD onset 3.0 ± 2.1 years participated. The mean EASI score was 8.9 ± 8.2, body surface area 13.1% ± 18.5%, pruritus score 5.9 ± 2.7, and Children Dermatology Life Quality Index 5.6 ± 4.9. pH and TEWL were higher at lesional compared to nonlesional skin, pH 5.2 ± 0.7 versus 4.6 ± 0.4, P < 0.01 and TEWL 31.1 ± 15.2 versus 16.0 ± 10.2, P < 0.01. Lesional pH positively correlated with TEWL (r = 0.59, P= 0.02 and r = 0.55, P = 0.01), while nonlesional pH was inversely correlated (r = −0.42,P = 0.04 and r = −0.40, P = 0.05). pH showed significant positive correlations with EASI and itch at one lesional site. Conclusion: pH and TEWL were higher at lesional skin. pH correlated positively with TEWL at lesional skin but inversely at nonlesional areas. Higher pH was associated with disease severity and itch. pH restoration may have therapeutic potential in AD." @default.
• W3103113323 created "2020-11-23" @default.
• W3103113323 creator A5005054775 @default.
• W3103113323 creator A5070042390 @default.
• W3103113323 date "2020-01-01" @default.
• W3103113323 modified "2023-10-01" @default.
• W3103113323 title "Skin pH and its relationship with transepidermal water loss and disease severity in children with atopic dermatitis: A cross-sectional study" @default.
• W3103113323 cites W1973650296 @default.
• W3103113323 cites W1978557166 @default.
• W3103113323 cites W1979267735 @default.
• W3103113323 cites W2003956410 @default.
• W3103113323 cites W2031517106 @default.
• W3103113323 cites W2058856302 @default.
• W3103113323 cites W2060891980 @default.
• W3103113323 cites W2065098180 @default.
• W3103113323 cites W2067548168 @default.
• W3103113323 cites W2127198432 @default.
• W3103113323 cites W2155819178 @default.
• W3103113323 cites W2207858477 @default.
• W3103113323 cites W2342027326 @default.
• W3103113323 cites W245689918 @default.
• W3103113323 cites W2732263256 @default.
• W3103113323 cites W2790318866 @default.
• W3103113323 cites W2973584376 @default.
• W3103113323 cites W4230846436 @default.
• W3103113323 doi "https://doi.org/10.4103/jdds.jdds_33_20" @default.
• W3103113323 hasPublicationYear "2020" @default.
• W3103113323 type Work @default.
• W3103113323 sameAs 3103113323 @default.
• W3103113323 citedByCount "2" @default.
• W3103113323 countsByYear W31031133232021 @default.
• W3103113323 countsByYear W31031133232022 @default.
• W3103113323 crossrefType "journal-article" @default.
• W3103113323 hasAuthorship W3103113323A5005054775 @default.
• W3103113323 hasAuthorship W3103113323A5070042390 @default.
• W3103113323 hasBestOaLocation W31031133231 @default.
• W3103113323 hasConcept C126322002 @default.
• W3103113323 hasConcept C142724271 @default.
• W3103113323 hasConcept C159110408 @default.
• W3103113323 hasConcept C16005928 @default.
• W3103113323 hasConcept C2777501473 @default.
• W3103113323 hasConcept C2778329239 @default.
• W3103113323 hasConcept C2778370115 @default.
• W3103113323 hasConcept C2779951463 @default.
• W3103113323 hasConcept C2780699399 @default.
• W3103113323 hasConcept C30036603 @default.
• W3103113323 hasConcept C71924100 @default.
• W3103113323 hasConcept C90924648 @default.
• W3103113323 hasConcept C95150158 @default.
• W3103113323 hasConceptScore W3103113323C126322002 @default.
• W3103113323 hasConceptScore W3103113323C142724271 @default.
• W3103113323 hasConceptScore W3103113323C159110408 @default.
• W3103113323 hasConceptScore W3103113323C16005928 @default.
• W3103113323 hasConceptScore W3103113323C2777501473 @default.
• W3103113323 hasConceptScore W3103113323C2778329239 @default.
• W3103113323 hasConceptScore W3103113323C2778370115 @default.
• W3103113323 hasConceptScore W3103113323C2779951463 @default.
• W3103113323 hasConceptScore W3103113323C2780699399 @default.
• W3103113323 hasConceptScore W3103113323C30036603 @default.
• W3103113323 hasConceptScore W3103113323C71924100 @default.
• W3103113323 hasConceptScore W3103113323C90924648 @default.
• W3103113323 hasConceptScore W3103113323C95150158 @default.
• W3103113323 hasIssue "2" @default.
• W3103113323 hasLocation W31031133231 @default.
• W3103113323 hasOpenAccess W3103113323 @default.
• W3103113323 hasPrimaryLocation W31031133231 @default.
• W3103113323 hasRelatedWork W2098581610 @default.
• W3103113323 hasRelatedWork W2151754510 @default.
• W3103113323 hasRelatedWork W2613543041 @default.
• W3103113323 hasRelatedWork W2993747767 @default.
• W3103113323 hasRelatedWork W3000863237 @default.
• W3103113323 hasRelatedWork W3110528957 @default.
• W3103113323 hasRelatedWork W3134434166 @default.
• W3103113323 hasRelatedWork W3158030853 @default.
• W3103113323 hasRelatedWork W4318069789 @default.
• W3103113323 hasRelatedWork W4362693581 @default.
• W3103113323 hasVolume "24" @default.
• W3103113323 isParatext "false" @default.
• W3103113323 isRetracted "false" @default.
• W3103113323 magId "3103113323" @default.
• W3103113323 workType "article" @default.