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• W3103181898 endingPage "848" @default.
• W3103181898 startingPage "836" @default.
• W3103181898 abstract "Abstract Heritable DNA methylation is a highly conserved epigenetic mark that is important for many biological processes. In a previous transcriptomic study on the fruit skin pigmentation of apple (Malus domestica Borkh.) cv. ‘Red Delicious’ (G0) and its four continuous-generation bud sport mutants including ‘Starking Red’ (G1), ‘Starkrimson’ (G2), ‘Campbell Redchief’ (G3) and ‘Vallee spur’ (G4), we identified MYB transcription factors (TFs) MdLUX and MdPCL-like involved in regulating anthocyanin synthesis. However, how these TFs ultimately determine the fruit skin color traits remains elusive. Here, bioinformatics analysis revealed that MdLUX and MdPCL-like contained a well-conserved motif SH[AL]QKY[RF] in their C-terminal region and were located in the nucleus of onion epidermal cells. Overexpression of MdLUX and MdPCL-like in ‘Golden Delicious’ fruits, ‘Gala’ calli and Arabidopsis thaliana promoted the accumulation of anthocyanin, whereas MdLUX and MdPCL-like suppression inhibited anthocyanin accumulation in ‘Red Fuji’ apple fruit skin. Yeast one-hybrid assays revealed that MdLUX and MdPCL-like may bind to the promoter region of the anthocyanin biosynthesis gene MdF3H. Dual-luciferase assays indicated that MdLUX and MdPCL-like activated MdF3H. The whole-genome DNA methylation study revealed that the methylation levels of the mCG context at the upstream (i.e., promoter region) of MdLUX and MdPCL-like were inversely correlated with their mRNA levels and anthocyanin accumulation. Hence, the data suggest that MYB_SH[AL]QKY[RF] TFs MdLUX and MdPCL-like promote anthocyanin biosynthesis in apple fruit skins through the DNA hypomethylation of their promoter regions and the activation of the structural flavonoid gene MdF3H." @default.
• W3103181898 created "2020-11-23" @default.
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• W3103181898 date "2020-11-10" @default.
• W3103181898 modified "2023-10-05" @default.
• W3103181898 title "MYB_SH[AL]QKY[RF] transcription factors <i>MdLUX</i> and <i>MdPCL-like</i> promote anthocyanin accumulation through DNA hypomethylation and <i>MdF3H</i> activation in apple" @default.
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• W3103181898 cites W1984891757 @default.
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• W3103181898 cites W2022684284 @default.
• W3103181898 cites W2024350112 @default.
• W3103181898 cites W2024848067 @default.
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• W3103181898 doi "https://doi.org/10.1093/treephys/tpaa156" @default.
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• W3103181898 hasPublicationYear "2020" @default.
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