Matches in SemOpenAlex for { <https://semopenalex.org/work/W3103500404> ?p ?o ?g. }
Showing items 1 to 100 of
100
with 100 items per page.
- W3103500404 abstract "Abstract A rich of 3,4‐ seco ‐lupane triterpenoids including chiisanoside (CSS), divaroside (DVS), sessiloside‐A1 (SSA) and chiisanogenin (CSG) were isolated from the ethanol extract of the leaves of Acanthopanax sessiliflorus . On the basis of previous studies, this article focused on four important components of 3,4‐ seco ‐lupane triterpenoids in Acanthopanax sessiliflorus leaves and explored their protective effects against aconitine‐induced cardiomyocyte injury and their molecular mechanisms. The results showed that pretreatment with 3,4‐ seco ‐lupane triterpenoids could effectively increase cell viability, reduce CK‐MB and LDH activities, reduce ROS production, maintain calcium concentration balance, and inhibit apoptosis, with divaroside having the best effect. In addition, Western blot results showed that divaroside down‐regulated Cleaved caspase‐3 and Bax and up‐regulated Bcl‐2 expression through activating the PI3 K/AKT pathway. However, the LY294002 inhibitor reversed this situation. This suggests that 3,4‐ seco ‐lupane triterpenoids may be a new hotspot for potential myocardial protective drugs research." @default.
- W3103500404 created "2020-11-23" @default.
- W3103500404 creator A5020748132 @default.
- W3103500404 creator A5024002121 @default.
- W3103500404 creator A5046176019 @default.
- W3103500404 creator A5056101043 @default.
- W3103500404 creator A5063253432 @default.
- W3103500404 creator A5074163608 @default.
- W3103500404 creator A5083746100 @default.
- W3103500404 creator A5087240893 @default.
- W3103500404 date "2020-12-14" @default.
- W3103500404 modified "2023-10-16" @default.
- W3103500404 title "Potential Myocardial Protection of 3,4‐ <i>seco</i> ‐Lupane Triterpenoids from <i>Acanthopanax sessiliflorus</i> Leaves" @default.
- W3103500404 cites W1191391069 @default.
- W3103500404 cites W1596302702 @default.
- W3103500404 cites W1972548076 @default.
- W3103500404 cites W1993889769 @default.
- W3103500404 cites W1996156970 @default.
- W3103500404 cites W2007114641 @default.
- W3103500404 cites W2033801757 @default.
- W3103500404 cites W2059611374 @default.
- W3103500404 cites W2070625178 @default.
- W3103500404 cites W2075148294 @default.
- W3103500404 cites W2100945775 @default.
- W3103500404 cites W2110174828 @default.
- W3103500404 cites W2130456414 @default.
- W3103500404 cites W2135314348 @default.
- W3103500404 cites W2165681130 @default.
- W3103500404 cites W2429678486 @default.
- W3103500404 cites W2601429121 @default.
- W3103500404 cites W2744377419 @default.
- W3103500404 cites W2791453970 @default.
- W3103500404 cites W2887386139 @default.
- W3103500404 cites W2898353163 @default.
- W3103500404 cites W2902617137 @default.
- W3103500404 cites W2912714421 @default.
- W3103500404 cites W3014674295 @default.
- W3103500404 cites W3049361756 @default.
- W3103500404 doi "https://doi.org/10.1002/cbdv.202000830" @default.
- W3103500404 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/33188566" @default.
- W3103500404 hasPublicationYear "2020" @default.
- W3103500404 type Work @default.
- W3103500404 sameAs 3103500404 @default.
- W3103500404 citedByCount "7" @default.
- W3103500404 countsByYear W31035004042022 @default.
- W3103500404 countsByYear W31035004042023 @default.
- W3103500404 crossrefType "journal-article" @default.
- W3103500404 hasAuthorship W3103500404A5020748132 @default.
- W3103500404 hasAuthorship W3103500404A5024002121 @default.
- W3103500404 hasAuthorship W3103500404A5046176019 @default.
- W3103500404 hasAuthorship W3103500404A5056101043 @default.
- W3103500404 hasAuthorship W3103500404A5063253432 @default.
- W3103500404 hasAuthorship W3103500404A5074163608 @default.
- W3103500404 hasAuthorship W3103500404A5083746100 @default.
- W3103500404 hasAuthorship W3103500404A5087240893 @default.
- W3103500404 hasConcept C107585567 @default.
- W3103500404 hasConcept C142724271 @default.
- W3103500404 hasConcept C185592680 @default.
- W3103500404 hasConcept C204787440 @default.
- W3103500404 hasConcept C2778770856 @default.
- W3103500404 hasConcept C2779232237 @default.
- W3103500404 hasConcept C2780527577 @default.
- W3103500404 hasConcept C44937612 @default.
- W3103500404 hasConcept C556039675 @default.
- W3103500404 hasConcept C71240020 @default.
- W3103500404 hasConcept C71924100 @default.
- W3103500404 hasConcept C86803240 @default.
- W3103500404 hasConcept C98274493 @default.
- W3103500404 hasConceptScore W3103500404C107585567 @default.
- W3103500404 hasConceptScore W3103500404C142724271 @default.
- W3103500404 hasConceptScore W3103500404C185592680 @default.
- W3103500404 hasConceptScore W3103500404C204787440 @default.
- W3103500404 hasConceptScore W3103500404C2778770856 @default.
- W3103500404 hasConceptScore W3103500404C2779232237 @default.
- W3103500404 hasConceptScore W3103500404C2780527577 @default.
- W3103500404 hasConceptScore W3103500404C44937612 @default.
- W3103500404 hasConceptScore W3103500404C556039675 @default.
- W3103500404 hasConceptScore W3103500404C71240020 @default.
- W3103500404 hasConceptScore W3103500404C71924100 @default.
- W3103500404 hasConceptScore W3103500404C86803240 @default.
- W3103500404 hasConceptScore W3103500404C98274493 @default.
- W3103500404 hasIssue "1" @default.
- W3103500404 hasLocation W31035004041 @default.
- W3103500404 hasOpenAccess W3103500404 @default.
- W3103500404 hasPrimaryLocation W31035004041 @default.
- W3103500404 hasRelatedWork W1989438376 @default.
- W3103500404 hasRelatedWork W1995971408 @default.
- W3103500404 hasRelatedWork W2024875922 @default.
- W3103500404 hasRelatedWork W2040161573 @default.
- W3103500404 hasRelatedWork W2041310043 @default.
- W3103500404 hasRelatedWork W2137229044 @default.
- W3103500404 hasRelatedWork W2781798884 @default.
- W3103500404 hasRelatedWork W2950684449 @default.
- W3103500404 hasRelatedWork W2953166940 @default.
- W3103500404 hasRelatedWork W2953304882 @default.
- W3103500404 hasVolume "18" @default.
- W3103500404 isParatext "false" @default.
- W3103500404 isRetracted "false" @default.
- W3103500404 magId "3103500404" @default.
- W3103500404 workType "article" @default.