FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W3104117584> ?p ?o ?g. }

• W3104117584 endingPage "15335" @default.
• W3104117584 startingPage "15323" @default.
• W3104117584 abstract "High-throughput glycan analysis has become an important part of biopharmaceutical production and quality control. However, it is still a significant challenge in the field of glycomics to easily deduce isomeric glycan structures, especially in a high-throughput manner. Ion mobility spectrometry (IMS) is an excellent tool for differentiating isomeric glycan structures. However, demonstrations of the utility of IMS in high-throughput workflows such as liquid chromatography-fluorescence-mass spectrometry (LC-FLR-MS) workflows have been limited with only a small amount of collision cross section (CCS) data available. In particular, IMS data of glycan fragments obtained in positive ion mode are limited in comparison to those obtained in negative ion mode despite positive ion mode being widely used for glycomics. Here, we describe IMS TWCCSN2 data obtained from a high-throughput LC-FLR-IMS-MS workflow in positive ion mode. We obtained IMS data from a selection of RapiFluor-MS (RFMS) labeled N-glycans and also glycopeptides. We describe how IMS is able to distinguish isomeric N-glycans and glycopeptides using both intact IMS and fragment-based IMS glycan sequencing experiments in positive ion mode, without significantly altering the high-throughput nature of the analysis. For the first time, we were able to successfully use IMS in positive ion mode to determine the branching of isomeric glycopeptides and RFMS labeled glycans. Further, we highlight that IMS glycan sequencing of fragments obtained from RFMS labeled glycans was similar to that of glycopeptides. Finally, we show that the IMS glycan sequencing approach can highlight shared structural features of nonisomeric glycans in a high-throughput LC-FLR-IMS-MS workflow." @default.
• W3104117584 created "2020-11-23" @default.
• W3104117584 creator A5001717824 @default.
• W3104117584 creator A5018781118 @default.
• W3104117584 creator A5022588504 @default.
• W3104117584 creator A5033850438 @default.
• W3104117584 creator A5060625212 @default.
• W3104117584 creator A5063051779 @default.
• W3104117584 creator A5064775072 @default.
• W3104117584 creator A5070616342 @default.
• W3104117584 creator A5082473050 @default.
• W3104117584 creator A5090728562 @default.
• W3104117584 date "2020-11-09" @default.
• W3104117584 modified "2023-09-30" @default.
• W3104117584 title "Utility of Ion-Mobility Spectrometry for Deducing Branching of Multiply Charged Glycans and Glycopeptides in a High-Throughput Positive ion LC-FLR-IMS-MS Workflow" @default.
• W3104117584 cites W145329232 @default.
• W3104117584 cites W1543891223 @default.
• W3104117584 cites W1966025897 @default.
• W3104117584 cites W1992066825 @default.
• W3104117584 cites W2004925055 @default.
• W3104117584 cites W2022338284 @default.
• W3104117584 cites W2034959888 @default.
• W3104117584 cites W2036276052 @default.
• W3104117584 cites W2057707130 @default.
• W3104117584 cites W2075166329 @default.
• W3104117584 cites W2094929667 @default.
• W3104117584 cites W2128053367 @default.
• W3104117584 cites W2129573030 @default.
• W3104117584 cites W2149603938 @default.
• W3104117584 cites W2155628978 @default.
• W3104117584 cites W2175291039 @default.
• W3104117584 cites W2250334067 @default.
• W3104117584 cites W2267724599 @default.
• W3104117584 cites W2284849326 @default.
• W3104117584 cites W2330451514 @default.
• W3104117584 cites W2493124561 @default.
• W3104117584 cites W2517906130 @default.
• W3104117584 cites W2534906623 @default.
• W3104117584 cites W2553651470 @default.
• W3104117584 cites W2571811979 @default.
• W3104117584 cites W2597467486 @default.
• W3104117584 cites W2598497411 @default.
• W3104117584 cites W2621637707 @default.
• W3104117584 cites W2741734362 @default.
• W3104117584 cites W2762757323 @default.
• W3104117584 cites W2789682399 @default.
• W3104117584 cites W2794525690 @default.
• W3104117584 cites W2801591477 @default.
• W3104117584 cites W2884507766 @default.
• W3104117584 cites W2886968306 @default.
• W3104117584 cites W2906859687 @default.
• W3104117584 cites W2912377866 @default.
• W3104117584 cites W2935888255 @default.
• W3104117584 cites W2939338539 @default.
• W3104117584 cites W2943349441 @default.
• W3104117584 cites W2948064926 @default.
• W3104117584 cites W2963972512 @default.
• W3104117584 cites W2966318873 @default.
• W3104117584 cites W2968996898 @default.
• W3104117584 cites W2977649203 @default.
• W3104117584 cites W3010947540 @default.
• W3104117584 cites W3098953572 @default.
• W3104117584 doi "https://doi.org/10.1021/acs.analchem.0c01954" @default.
• W3104117584 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/33166117" @default.
• W3104117584 hasPublicationYear "2020" @default.
• W3104117584 type Work @default.
• W3104117584 sameAs 3104117584 @default.
• W3104117584 citedByCount "24" @default.
• W3104117584 countsByYear W31041175842021 @default.
• W3104117584 countsByYear W31041175842022 @default.
• W3104117584 countsByYear W31041175842023 @default.
• W3104117584 crossrefType "journal-article" @default.
• W3104117584 hasAuthorship W3104117584A5001717824 @default.
• W3104117584 hasAuthorship W3104117584A5018781118 @default.
• W3104117584 hasAuthorship W3104117584A5022588504 @default.
• W3104117584 hasAuthorship W3104117584A5033850438 @default.
• W3104117584 hasAuthorship W3104117584A5060625212 @default.
• W3104117584 hasAuthorship W3104117584A5063051779 @default.
• W3104117584 hasAuthorship W3104117584A5064775072 @default.
• W3104117584 hasAuthorship W3104117584A5070616342 @default.
• W3104117584 hasAuthorship W3104117584A5082473050 @default.
• W3104117584 hasAuthorship W3104117584A5090728562 @default.
• W3104117584 hasConcept C106686826 @default.
• W3104117584 hasConcept C108625454 @default.
• W3104117584 hasConcept C137610392 @default.
• W3104117584 hasConcept C15213710 @default.
• W3104117584 hasConcept C162356407 @default.
• W3104117584 hasConcept C185592680 @default.
• W3104117584 hasConcept C206212055 @default.
• W3104117584 hasConcept C43617362 @default.
• W3104117584 hasConcept C501593827 @default.
• W3104117584 hasConcept C55493867 @default.
• W3104117584 hasConceptScore W3104117584C106686826 @default.
• W3104117584 hasConceptScore W3104117584C108625454 @default.
• W3104117584 hasConceptScore W3104117584C137610392 @default.
• W3104117584 hasConceptScore W3104117584C15213710 @default.
• W3104117584 hasConceptScore W3104117584C162356407 @default.
• W3104117584 hasConceptScore W3104117584C185592680 @default.

• next