Matches in SemOpenAlex for { <https://semopenalex.org/work/W3104319218> ?p ?o ?g. }
- W3104319218 abstract "Abstract The mechanisms by which noninvasive vagal nerve stimulation (nVNS) affect central and peripheral neural circuits that subserve pain and autonomic physiology are not clear, and thus remain an area of intense investigation. Effects of nVNS vs sham stimulation on subject responses to five noxious thermal stimuli (applied to left lower extremity), were measured in 30 healthy subjects (n=15 sham and n=15 nVNS), with fMRI and physiological galvanic skin response (GSR). With repeated noxious thermal stimuli a group × time analysis showed a significantly ( p < .001) decreased response with nVNS in bilateral primary and secondary somatosensory cortices (SI and SII), left dorsoposterior insular cortex, bilateral paracentral lobule, bilateral medial dorsal thalamus, right anterior cingulate cortex, and right orbitofrontal cortex. A group × time × GSR analysis showed a significantly decreased response in nVNS group ( p < .0005) in bilaterally in SI, lower and mid medullary brainstem, and inferior occipital cortex. Finally, nVNS treatment showed decreased activity in pronociceptive brainstem nuclei (e.g. the reticular nucleus and rostral ventromedial medulla) and key autonomic integration nuclei (e.g. the rostroventrolateral medulla, nucleus ambiguous, and dorsal motor nucleus of the vagus nerve). In aggregate, noninvasive vagal nerve stimulation reduced the physiological response to noxious thermal stimuli and impacted neural circuits important for pain processing and autonomic output." @default.
- W3104319218 created "2020-11-23" @default.
- W3104319218 creator A5004425236 @default.
- W3104319218 creator A5004993068 @default.
- W3104319218 creator A5012505521 @default.
- W3104319218 creator A5019851902 @default.
- W3104319218 creator A5021685813 @default.
- W3104319218 creator A5026708491 @default.
- W3104319218 creator A5033525987 @default.
- W3104319218 creator A5046673482 @default.
- W3104319218 creator A5055604009 @default.
- W3104319218 creator A5055835329 @default.
- W3104319218 creator A5060877653 @default.
- W3104319218 creator A5062183367 @default.
- W3104319218 creator A5069589143 @default.
- W3104319218 creator A5079391645 @default.
- W3104319218 date "2018-07-12" @default.
- W3104319218 modified "2023-09-27" @default.
- W3104319218 title "Noninvasive Vagus Nerve Stimulation Alters the Neural and Physiological Response to Noxious Thermal Challenge" @default.
- W3104319218 cites W1544532631 @default.
- W3104319218 cites W1552169386 @default.
- W3104319218 cites W1586418027 @default.
- W3104319218 cites W1937423926 @default.
- W3104319218 cites W1965026024 @default.
- W3104319218 cites W1966090527 @default.
- W3104319218 cites W1966752480 @default.
- W3104319218 cites W1967601775 @default.
- W3104319218 cites W1972929959 @default.
- W3104319218 cites W1974557531 @default.
- W3104319218 cites W1982668600 @default.
- W3104319218 cites W1983006199 @default.
- W3104319218 cites W1984173904 @default.
- W3104319218 cites W1985623917 @default.
- W3104319218 cites W1985927981 @default.
- W3104319218 cites W1989093731 @default.
- W3104319218 cites W1995971633 @default.
- W3104319218 cites W1996371627 @default.
- W3104319218 cites W1996974042 @default.
- W3104319218 cites W1997117942 @default.
- W3104319218 cites W1998975902 @default.
- W3104319218 cites W2002958204 @default.
- W3104319218 cites W2003102568 @default.
- W3104319218 cites W2006537950 @default.
- W3104319218 cites W2007605491 @default.
- W3104319218 cites W2008512583 @default.
- W3104319218 cites W2008784493 @default.
- W3104319218 cites W2012305168 @default.
- W3104319218 cites W2014587614 @default.
- W3104319218 cites W2015602085 @default.
- W3104319218 cites W2016521818 @default.
- W3104319218 cites W2018476121 @default.
- W3104319218 cites W2020224172 @default.
- W3104319218 cites W2021008834 @default.
- W3104319218 cites W2021459652 @default.
- W3104319218 cites W2022790148 @default.
- W3104319218 cites W2022857000 @default.
- W3104319218 cites W2024337244 @default.
- W3104319218 cites W2024665687 @default.
- W3104319218 cites W2024944353 @default.
- W3104319218 cites W2026049606 @default.
- W3104319218 cites W2028730979 @default.
- W3104319218 cites W2035091042 @default.
- W3104319218 cites W2035462451 @default.
- W3104319218 cites W2036876809 @default.
- W3104319218 cites W2041782733 @default.
- W3104319218 cites W2042634021 @default.
- W3104319218 cites W2047743315 @default.
- W3104319218 cites W2047917340 @default.
- W3104319218 cites W2049204635 @default.
- W3104319218 cites W2049857913 @default.
- W3104319218 cites W2053436213 @default.
- W3104319218 cites W2054495768 @default.
- W3104319218 cites W2055930098 @default.
- W3104319218 cites W2055942912 @default.
- W3104319218 cites W2057650108 @default.
- W3104319218 cites W2059151261 @default.
- W3104319218 cites W2061222262 @default.
- W3104319218 cites W2061874226 @default.
- W3104319218 cites W2063452278 @default.
- W3104319218 cites W2065240872 @default.
- W3104319218 cites W2065445243 @default.
- W3104319218 cites W2071317972 @default.
- W3104319218 cites W2075253677 @default.
- W3104319218 cites W2077374810 @default.
- W3104319218 cites W2077842462 @default.
- W3104319218 cites W2084501080 @default.
- W3104319218 cites W2085955270 @default.
- W3104319218 cites W2088992072 @default.
- W3104319218 cites W2089722232 @default.
- W3104319218 cites W2090202944 @default.
- W3104319218 cites W2090686529 @default.
- W3104319218 cites W2098647834 @default.
- W3104319218 cites W2100025455 @default.
- W3104319218 cites W2100399155 @default.
- W3104319218 cites W2103251342 @default.
- W3104319218 cites W2104748318 @default.
- W3104319218 cites W2110247921 @default.
- W3104319218 cites W2113217511 @default.
- W3104319218 cites W2117140276 @default.
- W3104319218 cites W2118789894 @default.