Matches in SemOpenAlex for { <https://semopenalex.org/work/W3104320748> ?p ?o ?g. }
- W3104320748 abstract "Abstract Spontaneous blink rate is considered a biomarker of central dopaminergic activity. Recent evidence suggests that the central dopaminergic system plays a role in nociception. In the present study, we aimed to investigate whether pain modulates spontaneous blink rate in healthy subjects. We enrolled 15 participants. Spontaneous blink rate was quantified with an optoelectronic system before and after: (1) a painful laser stimulation, and (2) an acoustic startling stimulation. In control experiments, we investigated whether laser stimulation effects depended on stimulation intensity and whether laser stimulation induced any changes in the blink reflex recovery cycle. Finally, we investigated any relationship between spontaneous blink rate modification and pain modulation effect during the cold pressor test. Laser, but not acoustic, stimulation increased spontaneous blink rate. This effect was independent of stimulation intensity and negatively correlated with pain perception. No changes in trigeminal-facial reflex circuit excitability were elicited by laser stimulation. The cold pressor test also induced an increased spontaneous blink rate. Our study provides evidence on the role of dopamine in nociception and suggests that dopaminergic activity may be involved in pain modulation. These findings lay the groundwork for further investigations in patients with pathological conditions characterized by dopaminergic deficit and pain." @default.
- W3104320748 created "2020-11-23" @default.
- W3104320748 creator A5000077437 @default.
- W3104320748 creator A5004706283 @default.
- W3104320748 creator A5018071089 @default.
- W3104320748 creator A5023994461 @default.
- W3104320748 creator A5027858233 @default.
- W3104320748 creator A5046961308 @default.
- W3104320748 creator A5049426253 @default.
- W3104320748 creator A5052113111 @default.
- W3104320748 creator A5081566432 @default.
- W3104320748 date "2020-11-17" @default.
- W3104320748 modified "2023-10-12" @default.
- W3104320748 title "Painful stimulation increases spontaneous blink rate in healthy subjects" @default.
- W3104320748 cites W1582206225 @default.
- W3104320748 cites W1601053906 @default.
- W3104320748 cites W1671641402 @default.
- W3104320748 cites W1860423306 @default.
- W3104320748 cites W1948978305 @default.
- W3104320748 cites W1964600015 @default.
- W3104320748 cites W1967367073 @default.
- W3104320748 cites W1970580671 @default.
- W3104320748 cites W1975294832 @default.
- W3104320748 cites W1978373556 @default.
- W3104320748 cites W1978660947 @default.
- W3104320748 cites W1983280978 @default.
- W3104320748 cites W1985013828 @default.
- W3104320748 cites W1990543487 @default.
- W3104320748 cites W1994311100 @default.
- W3104320748 cites W2000982397 @default.
- W3104320748 cites W2002190250 @default.
- W3104320748 cites W2011653800 @default.
- W3104320748 cites W2016794146 @default.
- W3104320748 cites W2019349377 @default.
- W3104320748 cites W2020188512 @default.
- W3104320748 cites W2028089722 @default.
- W3104320748 cites W2028953043 @default.
- W3104320748 cites W2030592335 @default.
- W3104320748 cites W2030715149 @default.
- W3104320748 cites W2040587465 @default.
- W3104320748 cites W2044860425 @default.
- W3104320748 cites W2049056319 @default.
- W3104320748 cites W2049899658 @default.
- W3104320748 cites W2050806352 @default.
- W3104320748 cites W2055217410 @default.
- W3104320748 cites W2059335277 @default.
- W3104320748 cites W2060005910 @default.
- W3104320748 cites W2067135396 @default.
- W3104320748 cites W2067993536 @default.
- W3104320748 cites W2070675937 @default.
- W3104320748 cites W2079491525 @default.
- W3104320748 cites W2090282154 @default.
- W3104320748 cites W2092634513 @default.
- W3104320748 cites W2095088925 @default.
- W3104320748 cites W2103486522 @default.
- W3104320748 cites W2112168407 @default.
- W3104320748 cites W2120446809 @default.
- W3104320748 cites W2121468873 @default.
- W3104320748 cites W2123638996 @default.
- W3104320748 cites W2125672535 @default.
- W3104320748 cites W2131403507 @default.
- W3104320748 cites W2141269611 @default.
- W3104320748 cites W2147241885 @default.
- W3104320748 cites W2149896569 @default.
- W3104320748 cites W2163366340 @default.
- W3104320748 cites W2185939060 @default.
- W3104320748 cites W2316324980 @default.
- W3104320748 cites W2339380590 @default.
- W3104320748 cites W2475924031 @default.
- W3104320748 cites W2560473265 @default.
- W3104320748 cites W2616750976 @default.
- W3104320748 cites W2763712963 @default.
- W3104320748 cites W2806187455 @default.
- W3104320748 cites W2898816311 @default.
- W3104320748 cites W2924438539 @default.
- W3104320748 cites W2983080904 @default.
- W3104320748 cites W2983656738 @default.
- W3104320748 cites W2983702404 @default.
- W3104320748 cites W2986933426 @default.
- W3104320748 cites W3004752557 @default.
- W3104320748 cites W3010213128 @default.
- W3104320748 cites W4237220447 @default.
- W3104320748 doi "https://doi.org/10.1038/s41598-020-76804-w" @default.
- W3104320748 hasPubMedCentralId "https://www.ncbi.nlm.nih.gov/pmc/articles/7672065" @default.
- W3104320748 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/33203984" @default.
- W3104320748 hasPublicationYear "2020" @default.
- W3104320748 type Work @default.
- W3104320748 sameAs 3104320748 @default.
- W3104320748 citedByCount "7" @default.
- W3104320748 countsByYear W31043207482021 @default.
- W3104320748 countsByYear W31043207482022 @default.
- W3104320748 countsByYear W31043207482023 @default.
- W3104320748 crossrefType "journal-article" @default.
- W3104320748 hasAuthorship W3104320748A5000077437 @default.
- W3104320748 hasAuthorship W3104320748A5004706283 @default.
- W3104320748 hasAuthorship W3104320748A5018071089 @default.
- W3104320748 hasAuthorship W3104320748A5023994461 @default.
- W3104320748 hasAuthorship W3104320748A5027858233 @default.
- W3104320748 hasAuthorship W3104320748A5046961308 @default.
- W3104320748 hasAuthorship W3104320748A5049426253 @default.