FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W3104407789> ?p ?o ?g. }

• W3104407789 endingPage "1782" @default.
• W3104407789 startingPage "1782" @default.
• W3104407789 abstract "Bacteria must be able to cope with harsh environments to survive. In Gram-negative bacteria like Pseudomonas species, resistance-nodulation-division (RND) transporters contribute to this task by pumping toxic compounds out of cells. Previously, we found that the RND system TtgABC of Pseudomonas putida KT2440 confers resistance to toxic metal chelators of the bipyridyl group. Here, we report that the incubation of a ttgB mutant in medium containing 2,2’-bipyridyl generated revertant strains able to grow in the presence of this compound. This trait was related to alterations in the pp_2827 locus (homolog of mexS in Pseudomonas aeruginosa). The deletion and complementation of pp_2827 confirmed the importance of the locus for the revertant phenotype. Furthermore, alteration in the pp_2827 locus stimulated expression of the mexEF-oprN operon encoding an RND efflux pump. Deletion and complementation of mexF confirmed that the latter system can compensate the growth defect of the ttgB mutant in the presence of 2,2’-bipyridyl. To our knowledge, this is the first report on a role of pp_2827 (mexS) in the regulation of mexEF-oprN in P. putida KT2440. The results expand the information about the significance of MexEF-OprN in the stress response of P. putida KT2440 and the mechanisms for coping with bipyridyl toxicity." @default.
• W3104407789 created "2020-11-23" @default.
• W3104407789 creator A5017046807 @default.
• W3104407789 creator A5021956343 @default.
• W3104407789 creator A5022745225 @default.
• W3104407789 creator A5046338886 @default.
• W3104407789 creator A5049614794 @default.
• W3104407789 creator A5058316982 @default.
• W3104407789 date "2020-11-14" @default.
• W3104407789 modified "2023-10-16" @default.
• W3104407789 title "Involvement of MexS and MexEF-OprN in Resistance to Toxic Ion Chelators in Pseudomonas putida KT2440" @default.
• W3104407789 cites W1512490310 @default.
• W3104407789 cites W1570742213 @default.
• W3104407789 cites W1600055072 @default.
• W3104407789 cites W1624162836 @default.
• W3104407789 cites W1763493835 @default.
• W3104407789 cites W1932296131 @default.
• W3104407789 cites W1968349170 @default.
• W3104407789 cites W1972918463 @default.
• W3104407789 cites W1973766391 @default.
• W3104407789 cites W1993720367 @default.
• W3104407789 cites W2029905686 @default.
• W3104407789 cites W2031738351 @default.
• W3104407789 cites W2036559697 @default.
• W3104407789 cites W2039869367 @default.
• W3104407789 cites W2043698490 @default.
• W3104407789 cites W2044569644 @default.
• W3104407789 cites W2054920102 @default.
• W3104407789 cites W2063137442 @default.
• W3104407789 cites W2085968148 @default.
• W3104407789 cites W2091252382 @default.
• W3104407789 cites W2098538750 @default.
• W3104407789 cites W2099679382 @default.
• W3104407789 cites W2111678991 @default.
• W3104407789 cites W2120905326 @default.
• W3104407789 cites W2126849248 @default.
• W3104407789 cites W2144722775 @default.
• W3104407789 cites W2149353640 @default.
• W3104407789 cites W2151077811 @default.
• W3104407789 cites W2158901379 @default.
• W3104407789 cites W2162146633 @default.
• W3104407789 cites W2167279371 @default.
• W3104407789 cites W2167517017 @default.
• W3104407789 cites W2170907626 @default.
• W3104407789 cites W2179324586 @default.
• W3104407789 cites W2253406006 @default.
• W3104407789 cites W2416085361 @default.
• W3104407789 cites W2597506409 @default.
• W3104407789 cites W3076633117 @default.
• W3104407789 cites W4211084001 @default.
• W3104407789 doi "https://doi.org/10.3390/microorganisms8111782" @default.
• W3104407789 hasPubMedCentralId "https://www.ncbi.nlm.nih.gov/pmc/articles/7697342" @default.
• W3104407789 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/33202537" @default.
• W3104407789 hasPublicationYear "2020" @default.
• W3104407789 type Work @default.
• W3104407789 sameAs 3104407789 @default.
• W3104407789 citedByCount "4" @default.
• W3104407789 countsByYear W31044077892021 @default.
• W3104407789 countsByYear W31044077892023 @default.
• W3104407789 crossrefType "journal-article" @default.
• W3104407789 hasAuthorship W3104407789A5017046807 @default.
• W3104407789 hasAuthorship W3104407789A5021956343 @default.
• W3104407789 hasAuthorship W3104407789A5022745225 @default.
• W3104407789 hasAuthorship W3104407789A5046338886 @default.
• W3104407789 hasAuthorship W3104407789A5049614794 @default.
• W3104407789 hasAuthorship W3104407789A5058316982 @default.
• W3104407789 hasBestOaLocation W31044077891 @default.
• W3104407789 hasConcept C104317684 @default.
• W3104407789 hasConcept C143065580 @default.
• W3104407789 hasConcept C188082640 @default.
• W3104407789 hasConcept C200082930 @default.
• W3104407789 hasConcept C203075996 @default.
• W3104407789 hasConcept C2780543182 @default.
• W3104407789 hasConcept C523546767 @default.
• W3104407789 hasConcept C54355233 @default.
• W3104407789 hasConcept C84597430 @default.
• W3104407789 hasConcept C86803240 @default.
• W3104407789 hasConcept C89423630 @default.
• W3104407789 hasConceptScore W3104407789C104317684 @default.
• W3104407789 hasConceptScore W3104407789C143065580 @default.
• W3104407789 hasConceptScore W3104407789C188082640 @default.
• W3104407789 hasConceptScore W3104407789C200082930 @default.
• W3104407789 hasConceptScore W3104407789C203075996 @default.
• W3104407789 hasConceptScore W3104407789C2780543182 @default.
• W3104407789 hasConceptScore W3104407789C523546767 @default.
• W3104407789 hasConceptScore W3104407789C54355233 @default.
• W3104407789 hasConceptScore W3104407789C84597430 @default.
• W3104407789 hasConceptScore W3104407789C86803240 @default.
• W3104407789 hasConceptScore W3104407789C89423630 @default.
• W3104407789 hasIssue "11" @default.
• W3104407789 hasLocation W31044077891 @default.
• W3104407789 hasLocation W31044077892 @default.
• W3104407789 hasLocation W31044077893 @default.
• W3104407789 hasLocation W31044077894 @default.
• W3104407789 hasLocation W31044077895 @default.
• W3104407789 hasOpenAccess W3104407789 @default.
• W3104407789 hasPrimaryLocation W31044077891 @default.
• W3104407789 hasRelatedWork W1586662827 @default.

• next